The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
On-line capillary zone electrophoresis-ion spray tandem mass spectrometry for the determination of dynorphins
Open accessAbstract
Capillary zone electrophoresis-mass spectrometry and capillary zone electrophoresis-tandem mass spectrometry with ionization at atmospheric pressure are demonstrated as being feasible for the separation and determination of small peptides such as dynorphins (1-6, 1-7, 1-8, 1-9) and leucine enkephalin at low picomole levels by full-scan mass spectrometry and tandem mass spectrometry and at the low femtomole range under selected ion monitoring conditions. Ion evaporation resulting from the ion spray liquid chromatography-mass spectrometry interface exhibits primarily molecular weight information as singly and multiply charged ions and is shown to be a sensitive and mild ionization method for peptides. The full-scan daughter ion mass spectrum of leucine enkephalin is shown to contain fragment ions consistent with the sequence of the peptide. Parent ion scanning in the tandem mass spectrometry mode is a promising technique for the screening of related peptides.
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Citations
Cites
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Hughes, J., Smith, T. W., Kosterlitz, H. W., Fothergill, L. A., Morgan, B. A., & Morris, H. R. (1975) · Nature · doi:10.1038/258577a0 · Cited by 3,806
Cited by
New developments in biochemical mass spectrometry: electrospray ionization
Smith, R. D., Loo, J. A., Edmonds, C. G., Barinaga, C. J., & Udseth, H. R. (1990) · Analytical Chemistry · doi:10.1021/ac00208a002 · Cited by 1,051
[22] Electrospray ionization mass spectrometry
Edmonds, C. G., & Smith, R. D. (1990) · Methods in Enzymology · doi:10.1016/0076-6879(90)93430-s · Cited by 508
Covey, T. R., Huang, E. C., & Henion, J. D. (1991) · Analytical Chemistry · doi:10.1021/ac00013a003 · Cited by 446
Self-citationHigh-performance capillary electrophoresis
Karger, B. L. (1989) · Nature · doi:10.1038/339641a0 · Cited by 318
Recent advances in capillary electrophoresis/electrospray/mass spectrometry
Banks, J. F. (1997) · ELECTROPHORESIS · doi:10.1002/elps.1150181216 · Cited by 308
Metadata
- Authors
- Lee, E. D., Mück, W., Henion, J. D., & Covey, T. R.
- Venue
- Journal of Chromatography A
- Publisher
- Elsevier BV
- Published
- 1988-12
- Volume
- 458
- Pages
- 313-321
- ISSN
- 0021-9673 (ISSN-L)
- OpenAlex
- W2093804891
- Cited by
- 209
- References
- 1
- FWCI
- 11.63
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Lee, E. D., Mück, W., Henion, J. D., & Covey, T. R. (1988). On-line capillary zone electrophoresis-ion spray tandem mass spectrometry for the determination of dynorphins. Journal of Chromatography A. https://doi.org/10.1016/s0021-9673(00)90575-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
