The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Cardio-histopathological observations on aborted equine fetuses infected with equid herpesvirus 1 (EHV-1).
Abstract
Twenty-five aborted equine fetuses infected with equid herpesvirus 1 (EHV-1) were examined cardio-histopathologically. The main changes in the heart consisted of interstitial myocarditis and intramyocardial vascular lesions accompanied by degeneration and necrosis of the cardiac myocytes. Vascular pathology of intramyocardial small arteries and arterioles was characterized by endothelial cell necrosis and fibrinoid changes in the media. Eosinophilic intranuclear inclusion bodies characteristic of herpesvirus infection were detected in the myocardial cells and macrophages within and around the inflammatory lesions and in the endothelial cells and medial smooth muscle cells of the damaged vessels. This observation, taken in conjunction with the fact that EHV-1 antigens were detected immunohistochemically in some myocardial and endothelial cells, provides morphological evidence in support of the viral aetiology of the cardiac lesions.
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“The aborted fetus shows multiple lesions, including subcutaneous edema, pulmonary edema and splenic enlargement (Corner et al., 1963; Machida et al., 1997).”
From The Pathogenesis and Immune Evasive Mechanisms of Equine Herpesvirus Type 1 (2021) · cites this paper as Machida et al., 1997
Citations
Cites
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Kelly, W. R. (1985) · Elsevier eBooks · doi:10.1016/b978-0-12-391602-0.50008-6 · Cited by 227
Endothelial cell infection and thrombosis in paralysis caused by equid herpesvirus-1: equine stroke.
Edington, N., Bridges, C. G., & Patel, J. R. (1986) · Archives of Virology · doi:10.1007/bf01314149 · Cited by 213
Myocardial diseases of animals.
Vleet, J. F. V., & Ferrans, V. J. (1986) · PubMed · Cited by 157
Edington, N., Smyth, B., & Griffiths, L. (1991) · Journal of Comparative Pathology · doi:10.1016/s0021-9975(08)80148-x · Cited by 123
Kelly, W. R. (1993) · Elsevier eBooks · doi:10.1016/b978-0-12-391606-8.50010-7 · Cited by 103
Comparative aspects of equine herpesviruses.
Studdert, M. J. (1974) · PubMed · Cited by 89
The pathology of equine virus abortion.
Westerfield, C., & Ww, D. (1946) · PubMed · Cited by 29
(1963) · PubMed · Cited by 15
Research works printed but not linked: 3
- Bak, 1981, A pathological survey on equine viral rhinopneumonitis occurred in Korea, Korean Journal of Veterinary Research, 21, 11
- Becker, 1991, Myocarditis, Vol. 2, 719
- Campbell, 1983, Equine herpesvirus type 1 (EHV1), Veterinary Bulletin, 53, 135
Cited by
Sorted by citations
The Pathogenesis and Immune Evasive Mechanisms of Equine Herpesvirus Type 1
Laval, K., Poelaert, K. C. K., Van Cleemput, J., Zhao, J., Vandekerckhove, A. P., Gryspeerdt, A. C., Garré, B., van der Meulen, K., Baghi, H. B., Dubale, H. N., et al. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.662686 · Cited by 54
Metadata
- Authors
- Machida, N., Taniguchi, T., Nakamura, T., & Kiryu, K.
- Affiliations
- Tokyo University of Agriculture and Technology (JP)
- Venue
- Journal of Comparative Pathology
- Publisher
- Elsevier BV
- Published
- 1997-05
- Volume
- 116
- Issue
- 4
- Pages
- 379-385
- ISSN
- 0021-9975 (ISSN-L)
- OpenAlex
- W1987618261
- Cited by
- 13
- References
- 9
- Citations by year
- 2023: 1 · 2021: 1 · 2020: 2 · 2018: 1 · 2013: 3
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Comparative Pathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Herpesvirus Infections and Treatments
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
- Health Sciences › Veterinary › Equine › Veterinary Equine Medical Research
- Keywords
- equine herpesvirus 1, interstitial myocarditis, endothelial cell necrosis, immunohistochemistry
- MeSH terms
- Abortion, Veterinary, Animals, Herpesvirus 1, Equid, Female, Fetal Diseases, Fetus, Herpesviridae Infections, Horse Diseases, Horses, Myocardium, Pregnancy
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Cardio-histopathological observations on aborted equine fetuses infected with equid herpesvirus 1 (EHV-1). https://app.cochat.ai/papers/10.1016/s0021-9975(97)80054-0
- The paper
- Machida, N., Taniguchi, T., Nakamura, T., & Kiryu, K. (1997). Cardio-histopathological observations on aborted equine fetuses infected with equid herpesvirus 1 (EHV-1). Journal of Comparative Pathology. https://doi.org/10.1016/s0021-9975(97)80054-0
