The DOI matches its Crossref record.
Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism
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In the citing paper
“in rodents and human HT-29 colon adenocarcinoma cells, piperine has been shown to inhibit glucuronidation of EGCG and 3-OH-benzo(a)pyrene at concentrations as low as 8 μM (Atal et al., 1985; Lambert et al., 2004).”
From Curcuminoids Inhibit Multiple Human Cytochromes P450, UDP-Glucuronosyltransferase, and Sulfotransferase Enzymes, whereas Piperine Is a Relatively Selective CYP3A4 Inhibitor (2008) · cites this paper as Atal et al., 1985
In the citing paper
“Other rodent studies have shown that piperine can inhibit both CYP and UGT activities in vivo (Atal et al., 1985; Reen and Singh, 1991).”
From Curcuminoids Inhibit Multiple Human Cytochromes P450, UDP-Glucuronosyltransferase, and Sulfotransferase Enzymes, whereas Piperine Is a Relatively Selective CYP3A4 Inhibitor (2008) · cites this paper as Atal et al., 1985
In the citing paper
“Piperine has been reported to inhibit the enzyme activity of cytochrome P450 (CYP) 3A4.”
From Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling (2024) · cites this paper as [9]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
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Citations
Cited by
Ayurveda and Traditional Chinese Medicine: A Comparative Overview
Patwardhan, B., Warude, D., Pushpangadan, P., & Bhatt, N. (2005) · Evidence-Based Complementary and Alternative Medicine · doi:10.1093/ecam/neh140 · Cited by 856
Black Pepper and its Pungent Principle-Piperine: A Review of Diverse Physiological Effects
Srinivasan, K. (2007) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390601062054 · Cited by 821
Volak, L. P., Ghirmai, S., Cashman, J. R., & Court, M. H. (2008) · Drug Metabolism and Disposition · doi:10.1124/dmd.108.020552 · Cited by 214
Gurley, B., Fifer, E., & Gardner, Z. (2012) · Planta Medica · doi:10.1055/s-0031-1298331 · Cited by 165
Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling
Lin, F., Hu, Y., Zhang, Y., Zhao, L., Zhong, D., & Liu, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252010955 · Cited by 20
Metadata
- Authors
- Atal, C. K., Dubey, R. K., & Singh, J.
- Venue
- The Journal of Pharmacology and Experimental Therapeutics
- Publisher
- Elsevier BV
- Published
- 1985-01
- Volume
- 232
- Issue
- 1
- Pages
- 258-262
- ISSN
- 0022-3565
- Cited by
- 180
- References
- 0
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
