Cited by 70Sleep and related disordersPharmaceutical Practices and Patient OutcomesObstructive Sleep Apnea Research

Are prescribed medications effective in the treatment of insomnia complaints?

Ohayon, Maurice M, Caulet, M, Arbus, L, Billard, M, Coquerel, A, Guieu, J.-D, Kullmann, B, Laffont, F +5 more·1999·Journal of Psychosomatic Research

Abstract

Although frequently investigated in the general population, the epidemiology of insomnia complaints and their treatment have received little attention in general practice. This study recruited patients > or =15 years of age, consecutively, from 127 general practitioners in France. The physicians collected data from 11,810 of their patients, of whom 55.5% were women. Insomnia complaints were reported by 26.2% (25.4% to 27%) of the sample and use of sleep-promoting medication by 10.1% (9.7% to 10.7%). About 47% of the prescribed drugs used were anxiolytics and 45% hypnotics. Most consumers took sleep-enhancing drugs on a daily and long-term basis and most reported that the medication improved their quality of sleep. However, few distinctions emerged between elderly drug-taking insomniacs and elderly nontreated insomniacs with respect to the various dimensions of sleep. Results underscore the persistent general tendency among French general practitioners to overprescribe anxiolytics for the treatment of insomnia complaints and that they do so on a long-term basis, despite the findings of numerous studies showing that benzodiazepines are ineffective in the treatment of sleep complaints over the long term.

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Crossref · 10.1016/s0022-3999(98)00079-8

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  • In clinical practice, hypnotic medications are often used over durations of one to twelve months without dosage escalation.

    “In clinical practice, hypnotic medications are often used over durations of one to twelve months without dosage escalation, 52-55”

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References 32 · Cited by 70

Authors
Ohayon, M. M., Caulet, M., Arbus, L., Billard, M., Coquerel, A., Guieu, J.-D., Kullmann, B., Laffont, F., Lemoine, P., Paty, J., Pechadre, J. C., Vecchierini, M.-F., & Vespignani, H.
Affiliations
  • Institut national de psychiatrie légale Philippe-Pinel (CA)
  • Hôpital Rangueil (FR)
  • Hôpital Gui de Chauliac (FR)
  • Hôpital Charles-Nicolle (FR)
  • Centre Hospitalier Universitaire de Lille (FR)
  • Pitié-Salpêtrière Hospital (FR)
  • Centre Hospitalier Le Vinatier (FR)
  • Hôpital Pellegrin (FR)
  • Hôpital Bichat-Claude-Bernard (FR)
  • Hôpital Saint-Julien (FR)
Corresponding author
Ohayon, Maurice M
Venue
Journal of Psychosomatic Research
Publisher
Elsevier BV
Published
1999-10
Volume
47
Issue
4
Pages
359-368
ISSN
0022-3999 (ISSN-L)
OpenAlex
W2026263413
Cited by
70
References
32
Citations by year
2026: 1 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 4 · 2012: 1
FWCI
3.43
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Psychosomatic Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
  • Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
Keywords
insomnia, anxiolytics, hypnotics, benzodiazepines, overprescribing, long-term drug use, general practice, elderly patients, sleep quality, primary care prescribing
MeSH terms
Adolescent, Adult, Aged, Family Practice, Female, France, Humans, Hypnotics and Sedatives, Sleep Initiation and Maintenance Disorders, Male, Middle Aged, Practice Patterns, Physicians', Population Surveillance, Psychotropic Drugs, Anti-Anxiety Agents, Prevalence, Case-Control Studies, Age Distribution, Sex Distribution, Drug Utilization Review

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