Electron diffraction and electron probe microanalysis of the mineral phase of bone tissue prepared by anhydrous techniques

A STUDY OF THE TISDALL METHOD FOR THE DETERMINATION OF BLOOD SERUM CALCIUM WITH A SUGGESTED MODIFICATION

Clark, E. P., & Collip, J. B. (1925) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)85009-8 · Cited by 970

Mitochondria and calcium ion transport

Lehninger, A. L. (1970) · Biochemical Journal · doi:10.1042/bj1190129 · Cited by 835

Calcification in Biological Systems

Copp, D. H. (1961) · Archives of Oral Biology · doi:10.1016/0003-9969(61)90120-0 · Cited by 705

THE DETERMINATION OF PHOSPHORUS AND PHOSPHATASE WITH N-PHENYL-p-PHENYLENEDIAMINE

Dryer, R. L., Tammes, A. R., & Routh, J. I. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64920-8 · Cited by 460

Molecular Biology of Mineralized Tissues with Particular Reference to Bone

Glimcher, M. J. (1959) · Reviews of Modern Physics · doi:10.1103/revmodphys.31.359 · Cited by 393

EFFECT OF ACTIVE ACCUMULATION OF CALCIUM AND PHOSPHATE IONS ON THE STRUCTURE OF RAT LIVER MITOCHONDRIA

Greenawalt, J. W., Rossi, C. S., & Lehninger, A. L. (1964) · The Journal of Cell Biology · doi:10.1083/jcb.23.1.21 · Cited by 378

The Nature of the Mineral Phase of Bone.

Neuman, W. F., & Neuman, M. W. (1953) · Chemical Reviews · doi:10.1021/cr60164a001 · Cited by 354

Infrared Analysis of Rat Bone: Age Dependency of Amorphous and Crystalline Mineral Fractions

Termine, J. D., & Posner, A. S. (1966) · Science · doi:10.1126/science.153.3743.1523 · Cited by 320

An electron microscopic study of initial intramembranous osteogenesis

Bernard, G. W., & Pease, D. C. (1969) · American Journal of Anatomy · doi:10.1002/aja.1001250303 · Cited by 302

Amorphous/crystalline interrelationships in bone mineral

Termine, J. D., & Posner, A. S. (1967) · Calcified Tissue International · doi:10.1007/bf02008070 · Cited by 296

Anionic Effects on the Size and Shape of Apatite Crystals Grown from Physiological Solutions

Eanes, E. D., & Hailer, A. W. (2000) · Calcified Tissue International · doi:10.1007/s002230010090 · Cited by 22

Calcium Transport Mechanism in Molting Crayfish Revealed by Microanalysis

Mizuhira, V., & Ueno, M. (1983) · Journal of Histochemistry & Cytochemistry · doi:10.1177/31.1a_suppl.6131091 · Cited by 22

Calcification and silicification: a comparative survey of the early stages of biomineralization

BONUCCI, E. (2009) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-009-0061-y · Cited by 21

Towards new material biomarkers for fracture risk

Greenwood, C., Clement, J. G., Dicken, A., Evans, P., Lyburn, I. D., Martin, R. M., Rogers, K. D., Stone, N., & Zioupos, P. (2016) · Bone · doi:10.1016/j.bone.2016.09.006 · Cited by 21

Cartilage Calcification Studied by Proton Nuclear Magnetic Resonance Microscopy

Potter, K., Leapman, R. D., Basser, P. J., & Landis, W. J. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.4.652 · Cited by 21

The Mineralization of Bone and Its Analogies with Other Hard Tissues

BONUCCI, E. (2013) · InTech eBooks · doi:10.5772/54591 · Cited by 19

The Three-Dimensional Spatial Relationship Between the Collagen Fibrils and the Inorganic Calcium-Phosphate Crystals of Pickerel and Herring Fish Bone

Lee, D. D., & Glimcher, M. J. (1989) · Connective Tissue Research · doi:10.3109/03008208909050014 · Cited by 19

Mitochondrial calcium of intact and mechanically damaged bone and cartilage cells studied with K-pyroantimonate

Burger, E. H., & de Bruijn, W. C. (1979) · Histochemistry and Cell Biology · doi:10.1007/bf00508360 · Cited by 18

Experimental hydroxyapatite synovial and articular cartilage calcification. light and electron microscopic studies

Reginato, A. J., Schumacher, H. R., & Brighton, C. T. (1982) · Arthritis & Rheumatism · doi:10.1002/art.1780251013 · Cited by 18

Biomimetic Fabrication of Apatite Related Biomaterials

Hafiz, M., Matsumoto, T., Okazaki, M., Nakahira, A., & Sohmur, T. (2010) · InTech eBooks · doi:10.5772/8777 · Cited by 18

Microstructural Features of Non-Union of Human Humeral Shaft Fracture

Wen, H. B., Cui, F. Z., & Zhu, X. D. (1997) · Journal of Structural Biology · doi:10.1006/jsbi.1997.3890 · Cited by 17

X-ray microanalysis: a histochemical tool for elemental analysis

Sumner, A. T. (1983) · The Histochemical Journal · doi:10.1007/bf01954144 · Cited by 16

Ultrastructural concepts on biological calcification; Focused on matrix vesicles.

Ozawa, H. (1985) · Japanese Journal of Oral Biology · doi:10.2330/joralbiosci1965.27.751 · Cited by 15

Calcium in osteoblast-enriched bone cells

Imai, K., Neuman, M. W., Kawase, T., & Saito, S. (1992) · Bone · doi:10.1016/8756-3282(92)90200-g · Cited by 15

Calcium Phosphate Deposition Disease in Great Danes

Woodard, J. C., Shields, R. P., Aldrich, H. C., & Carter, R. L. (1982) · Veterinary Pathology · doi:10.1177/030098588201900503 · Cited by 15

Atomic scale imaging of hydroxyapatite and brushite in air by force microscopy

Siperko, L. M., & Landis, W. J. (1992) · Applied Physics Letters · doi:10.1063/1.108146 · Cited by 15

ELECTRON PROBE X-RAY MICROANALYSIS OF NORMAL AND INJURED MYOCARDIUM: METHODS AND RESULTS

Hagler, H. K., Burton, K. P., & Buja, L. M. (1981) · Elsevier eBooks · doi:10.1016/b978-0-12-362880-0.50014-4 · Cited by 15

Osteogenic Cell Cultures Cannot Utilize Exogenous Sources of Synthetic Polyphosphate for Mineralization

Ariganello, M. B., Omelon, S. J., Variola, F., Wazen, R. M., Moffatt, P., & Nanci, A. (2014) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24886 · Cited by 14

Precipitation of Inorganic Salts in Mitochondrial Matrix

Jasielec, J. J., Filipek, R., Dołowy, K., & Lewenstam, A. (2020) · Membranes · doi:10.3390/membranes10050081 · Cited by 14

Cross-correlative 3D micro-structural investigation of human bone processed into bone allografts

Singh, A. K., Gajiwala, A. L., Rai, R. K., Khan, M. P., Singh, C., Barbhuyan, T. K., Vijayalakshmi, S., Chattopadhyay, N., Sinha, N., Kumar, A., et al. (2016) · Materials Science and Engineering C · doi:10.1016/j.msec.2016.02.002 · Cited by 14

Visualization of sulfur‐containing components associated with proliferating chondrocytes from rat epiphyseal growth plate cartilage: Possible proteoglycan and collagen co‐migration

Landis, W. J., & Hodgens, K. J. (1990) · The Anatomical Record · doi:10.1002/ar.1092260205 · Cited by 14

Calcium phosphate deposits in domes of human pancreatic adenocarcinoma (Capan‐1) cell cultures

HOLLANDE, E., Donato, J. ́. L. D., Fanjul, M., Palevody, C., Daumas, M., Puech, J., & Ratovo, G. (1990) · Biology of the Cell · doi:10.1016/0248-4900(90)90345-4 · Cited by 14

Surface poisoning of synthetic and biological apatites

Blumenthal, N. C., & Posner, A. S. (1987) · Colloids and Surfaces · doi:10.1016/0166-6622(87)80111-7 · Cited by 14

Ultrastructural and histochemical aspects of zinc accumulation by fish scales

Sauer, G. R., & Watabe, N. (1989) · Tissue and Cell · doi:10.1016/0040-8166(89)90044-x · Cited by 13

Demonstration of mitochondrial mineral deposits in osteoblasts after anhydrous fixation and processing

Manston, J., & Katchburian, E. (1984) · Journal of Microscopy · doi:10.1111/j.1365-2818.1984.tb02508.x · Cited by 13

Collagen Suprafibrillar Confinement Drives the Activity of Acidic Calcium-Binding Polymers on Apatite Mineralization

Silvent, J., Robin, M., Tovani, C. B., Wang, Y., Soncin, F., Delgado, S., Azaı̈s, T., Sassoye, C., Giraud‐Guille, M., Sire, J., et al. (2021) · Biomacromolecules · doi:10.1021/acs.biomac.1c00206 · Cited by 12

Changes in bone mineral in experimentally induced rickets in the rat: Electron microprobe and chemical studies

Dempster, D. W., Elder, H. Y., Nicholson, W. A. P., Smith, D. A., & Moss, V. A. (1980) · Calcified Tissue International · doi:10.1007/bf02408618 · Cited by 12

Styletogenesis in nemertean worms: The ultrastructure of organelles involved in intracellular calcification

Stricker, S. A. (1984) · Journal of Morphology · doi:10.1002/jmor.1051790202 · Cited by 12

Cortical Bone Mechanics and Composition: Effects of Age and Gender

Wang, X. (2011) · Studies in mechanobiology, tissue engineering and biomaterials · doi:10.1007/8415_2011_108 · Cited by 12

Ultrastructural Organic-Inorganic Relationships in Calcified Tissues: Cartilage and Bone vs. Enamel

BONUCCI, E. (1995) · Connective Tissue Research · doi:10.3109/03008209509016996 · Cited by 12

The electron microscopic structure of the osteoblast

Scherft, J. P., & Groot, C. G. (1990) · Springer eBooks · doi:10.1007/978-1-4613-1487-5_11 · Cited by 12

Toward understanding the cellular control of vertebrate mineralization: The potential role of mitochondria

Shapiro, I. M., Risbud, M. V., & Landis, W. J. (2024) · Bone · doi:10.1016/j.bone.2024.117112 · Cited by 12

Hydroxylapatite lattice preferred orientation in bone: a study of macaque, human and bovine samples

Voltolini, M., Wenk, H. R., Barreiro, J. G., & Agarwal, S. C. (2011) · Journal of Applied Crystallography · doi:10.1107/s0021889811024344 · Cited by 11

Mitochondrial matrix granules in soft tissues

Barnard, T., & Ruusa, J. (1979) · Experimental Cell Research · doi:10.1016/0014-4827(79)90209-x · Cited by 11

Fibrogenesis imperfecta ossium (Baker’s disease): a case studied at autopsy

SISSONS, H. A. (2000) · Bone · doi:10.1016/s8756-3282(00)00401-4 · Cited by 11

X-ray microanalysis of mineralized matrix vesicles of experimental saccular aneurysms

Greenhill, N. S., Presland, M. R., Rogers, K. M., & Stehbens, W. E. (1985) · Experimental and Molecular Pathology · doi:10.1016/0014-4800(85)90042-5 · Cited by 11

Preparation of hybrid samples for scanning electron microscopy (SEM) coupled to focused ion beam (FIB) analysis: A new way to study cell adhesion to titanium implant surfaces

Parisi, L., Toffoli, A. S., Ghezzi, B., Lagonegro, P., Trevisi, G., & Macaluso, G. M. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272486 · Cited by 10

Characterizing Mineral Ellipsoids in New Bone Formation at the Interface of Ti6Al4V Porous Implants

Deering, J., Chen, J., Mahmoud, D., Tang, T., Lin, Y., Fang, Q., Wohl, G. R., Elbestawi, M. A., & Grandfield, K. (2023) · Advanced Materials Interfaces · doi:10.1002/admi.202300333 · Cited by 10

Measurements of Energetic States Resulting from Ion Exchanges in the Isomorphic Crystals of Apatites and Bioapatites

Kuczumow, A., Blicharski, T., Gorzelak, M., Kosiński, J., Lasota, A., Gągała, J., Nowak, J., Jarzębski, M., & Jabłoński, M. (2022) · Molecules · doi:10.3390/molecules27248913 · Cited by 10

Cartilage Calcification

BONUCCI, E., & Gómez, S. (2012) · InTech eBooks · doi:10.5772/31249 · Cited by 10

Atomic force microscopy imaging of hydroxyapatite

Siperko, L. M., & Landis, W. J. (1993) · Journal of Materials Science Letters · doi:10.1007/bf00420523 · Cited by 10

Ultrastructural and cytochemical aspects of the initial phases of an experimental cutaneous calcinosis (calcergy) in the rat

Walzer, C., Boivin, G., Sch�nborner, A. A., & BAUD, C. A. (1980) · Cell and Tissue Research · doi:10.1007/bf00233954 · Cited by 10

Understanding Nanocalcification: A Role Suggested for Crystal Ghosts

BONUCCI, E. (2014) · Marine Drugs · doi:10.3390/md12074231 · Cited by 9

Ultrastructure of quick‐frozen and freeze‐substituted chick osteoclasts

Akisaka, T., Miyaji, T., Yoshida, H., & INOUE, M. (1997) · Journal of Anatomy · doi:10.1046/j.1469-7580.1997.19030433.x · Cited by 9

Three-dimensional analysis of mineralizing turkey leg tendon: Matrix vesicle-collagen relationships

Kohler, D. M., Crenshaw, M. A., & Arsenault, A. L. (1995) · Matrix Biology · doi:10.1016/s0945-053x(05)80003-4 · Cited by 9

Liposome interactions with hydroxyapatite crystals: A possible mechanism in the calcification of atherosclerotic plaques

Hirsch, D., Landis, W. J., Azoury, R., & Sarig, S. (1992) · Calcified Tissue International · doi:10.1007/bf00296291 · Cited by 9

Visualisation of methacrylate‐embedded human bone sections by infrared nanoscopy

Geith, T., Amarie, S., Milz, S., Bamberg, F., & Keilmann, F. (2013) · Journal of Biophotonics · doi:10.1002/jbio.201200172 · Cited by 8

Tubule formation and elemental detection in developing opossum enamel

Stern, D. N., Song, M. J., & Landis, W. J. (1992) · The Anatomical Record · doi:10.1002/ar.1092340105 · Cited by 8

Syndecan-3 in limb skeletal development

Kosher, R. A. (1998) · Microscopy Research and Technique · doi:10.1002/(sici)1097-0029(19981015)43:2 · Cited by 43

Calcium transport mechanism in crayfish gastrolith epithelium correlated with the molting cycle. I. The demonstration of calcium-accumulating sites.

UENO, M., & Mizuhira, V. (1983) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.16.596 · Cited by 8

Combination of phytase and citric acid, but not phytase alone, ensures regular rates of growth and bone mineralization in quails under severe phosphorus restriction

Vieira, B. S., Caramori, J. G., Corrêa, G. S. S., Colvara, I. G., Brusamarelo, E., Pereira, T. V. D. S., Barbosa, S. A., & de Oliveira, C. F. S. (2019) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13074 · Cited by 7

Oxidation processes on stoichiometric and nonstoichiometric hydroxyapatites

Hayashi, H., Kanai, H., Matsumura, Y., Sugiyama, S., & MOFFAT, J. B. (1997) · Studies in surface science and catalysis · doi:10.1016/s0167-2991(97)81029-4 · Cited by 7

A collagen-based laboratory model to mimic sex-specific features of calcific aortic valve disease

Allgayer, R., Kabir, R., Bergeron, A., Demers, P., Mantovani, D., & Cerruti, M. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.01.034 · Cited by 5

Unraveling the role of carboxylate groups and elastin particle size in medial calcification

Song, T., & Cerruti, M. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133267 · Cited by 6

The ultrastructure of calcified tissues: Methods and technical problems

Arsenault, A. L. (1990) · Springer eBooks · doi:10.1007/978-1-4613-1487-5_1 · Cited by 6

Discoidin domain receptor 2 activation of p38 mitogen-activated protein kinase as an important pathway for osteonectin-regulating osteoblast mineralization

Zhu, Y., Zhang, J., Mo, T., Jiang, C., Ma, R.-C., & Chen, L. (2021) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-021-02860-1 · Cited by 6

Single Bovine Enamel Particles Examined by Electron Optics

Landis, W. J., Navarro, M. F. D. L., Neuringer, J. R., & Kurz, K. (1984) · Journal of Dental Research · doi:10.1177/00220345840630050401 · Cited by 6

Effects of Surface Roughness and Maximum Load on the Mechanical Properties of Cancellous Bone Measured by Nanoindentation

Donnelly, E. L., Baker, S. P., Boskey, A. L., & van der Meulen, M. C. H. (2004) · MRS Proceedings · doi:10.1557/proc-823-w8.5 · Cited by 6

Atomic force microscopic determination of substrate effects on the structure of deposited biomineral phosphates

Siperko, L. M., & Landis, W. J. (1994) · The Analyst · doi:10.1039/an9941901935 · Cited by 6

3D scaffold induces efficient bone repair: in vivo studies of ultra-structural architecture at the interface

Sagar, N., Singh, A. K., Temgire, M., Vijayalakshmi, S., Dhawan, A., Kumar, A., Chattopadhyay, N., & Bellare, J. (2016) · RSC Advances · doi:10.1039/c6ra20420a · Cited by 5

Transformation of amorphous calcium phosphate to dicalcium phosphate dihydrate in phosphate solutions at physiological pH.

Doi, Y., & Eanes, E. D. (1987) · Japanese Journal of Oral Biology · doi:10.2330/joralbiosci1965.29.25 · Cited by 5

Calcified tissue histochemistry: from microstructures to nanoparticles

BONUCCI, E. (2009) · European Journal of Histochemistry · doi:10.4081/921 · Cited by 4

Limitations of ZAF Correction Factors in the Determination of Calcium/Phosphorus Ratios: Important Forensic Science Considerations Relevant to the Analysis of Bone Fragments Using Scanning Electron Microscopy and Energy-Dispersive X-Ray Microanalysis

Payne, C., & Cromey, D. W. (1990) · Journal of Forensic Sciences · doi:10.1520/jfs12862j · Cited by 4

Biomimetic Mineralization of an Aligned, Self-Assembled Collagenous Matrix.

Christiansen, D. L., & Silver, F. H. (1991) · MRS Proceedings · doi:10.1557/proc-255-367 · Cited by 4

MICROANALYSIS OF MITOCHONDRIAL GRANULES. MICROANALYSIS OF MITOCHONDRIAL GRANULES IN BONE CELLS INCIDENT TO EXPERIMENTAL TOOTH MOVEMENT

Hirashita, A., Nakamura, Y., OKUMURA, E., & Kuwabara, Y. (1980) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.13.343 · Cited by 4

Cancer in the Spine

Markman, M., McLain, R. F., Markman, M., Macklis, R. M., Lewandrowski, K., Bukowski, R. M., & Benzel, E. C. (2006) · Humana Press eBooks · doi:10.1007/978-1-59259-971-4 · Cited by 3

Electron microscopical x-ray microanalysis of mineralization nodules and several other tissue compartments in fetal bone

Groot, C. G. (1982) · Metabolic Bone Disease and Related Research · doi:10.1016/0221-8747(82)90020-0 · Cited by 3

Effects of Metal Ions on Apatite Formation and Bone Mineralization

Blumenthal, N. C., & Cosma, V. (1991) · MRS Proceedings · doi:10.1557/proc-252-29 · Cited by 2

Atomic Force Microscopic Imaging of Biologically Important Materials

Siperko, L. M., & Landis, W. J. (1992) · MRS Proceedings · doi:10.1557/proc-295-243 · Cited by 2

Hydroxyapatite as a material for transplantology: clinical experience and prospects of application

Markelov, V. A., Danilko, K. V., Solntzev, V., Piatnitskaia, S., Shangina, O., Bilyalov, A., Chugunov, S. S., & Akhatov, I. (2026) · Russian Journal of Transplantology and Artificial Organs · doi:10.15825/1995-1191-2026-1-263-275 · Cited by 1

Methodology

(2007) · Springer eBooks · doi:10.1007/978-3-540-36013-1_3 · Cited by 1

Bone Composition and Structure

Wang, X., Nyman, J. S., Dong, X., Leng, H., & Reyes, M. (2010) · Synthesis lectures on tissue engineering · doi:10.1007/978-3-031-02579-2_2 · Cited by 1

Intracellular Calcium in Mineralizing Tissues

Burger, E. H. (1981) · Springer eBooks · doi:10.1007/978-3-642-67916-2_107 · Cited by 1

Atomic Force Microscopic Imaging of Biomineral Powder Samples Formed by Deposits from Ethanolic Suspensions

Siperko, L. M., & Landis, W. J. (1994) · Springer eBooks · doi:10.1007/978-1-4757-9322-2_10

Once Upon a Sheep: A SEM Analysis of Ovine Patellar Enthesis

Tomerlin, B. M. (2012)

A Novel Self-Assembled Collagenous Matrix which Serves as a Template for Oriented Growth of Hydroxyapatite Crystal

Christiansen, D. L., Pins, G. D., Huang, E. K., & Silver, F. H. (1995) · MRS Proceedings · doi:10.1557/proc-414-29

Bone Formation: The Rules for Fabricating a Composite Ceramic

Caplan, A. I. (1989) · MRS Proceedings · doi:10.1557/proc-174-9

Mineral deposition and maturation during bone development

Lange, C. (2011) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-6204

Laboratory Studies and Diagnostic Work-Up of Bony Lesions in the Spine

Lewandrowski, K., McLain, R. F., & Mankin, H. J. (2008) · Humana Press eBooks · doi:10.1007/978-1-59259-971-4_11

Growth, structure and mechanical properties of phosphate based bio-composites studied by ex situ and in situ Raman spectroscopy

Chatzipanagis, K. (2016) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)

Collagenous Mineralized Tissues: Composition, Structure, and Biomineralization

Beniash, E. (2021) · Biology of extracellular matrix · doi:10.1007/978-3-030-76283-4_3

The Nature and Composition of the Inorganic Phase

(2007) · Springer eBooks · doi:10.1007/978-3-540-36013-1_4

The Shape of Inorganic Particles

(2007) · Springer eBooks · doi:10.1007/978-3-540-36013-1_5

[Surgery for benign schwannoma arising at the thoracic apex].

Takata, M., & Miyamoto, Y. (2013) · PubMed

Application of electron probe X-ray microanalysis to calcification studies of bone and cartilage.

Landis, W. J. (1979) · PubMed · Cited by 20

The solid, calcium-phosphate mineral phases in embryonic chick bone characterized by high-voltage electron diffraction

Lee, D. D. D., Landis, W. J., & Glimcher, M. J. (1986) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650010507 · Cited by 43

Electron microscopic observations of bone tissue prepared anhydrously in organic solvents

Landis, W. J., Paine, M. C., & Glimcher, M. J. (1977) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(77)80025-7 · Cited by 187

Demineralization of bone matrix: Observations from electron microscope and electron-probe analysis

Thorogood, P., & Gray, J. C. (1975) · Calcified Tissue International · doi:10.1007/bf02563987 · Cited by 24

Electron spectroscopic diffraction and imaging of the early and mature stages of calcium phosphate formation in the epiphyseal growth plate

Barckhaus, R. H., Höhling, H. J., Fromm, I., Hirsch, P. B., & Reimer, L. (1991) · Journal of Microscopy · doi:10.1111/j.1365-2818.1991.tb03126.x · Cited by 19