The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEM
Abstract
PURPOSE: We characterize the genetic abnormalities associated with pathological subtypes of renal tumors, which may help diagnosis or prognostication. MATERIALS AND METHODS: A comprehensive literature review of genetic abnormalities associated with different renal tumor subtypes was performed. RESULTS: Studies of sporadic and hereditary forms suggest that abnormalities in the von Hippel-Lindau and met genes are the earliest changes in conventional (clear cell) and papillary basophilic renal cancers, respectively. Renal oncocytoma and chromophobe carcinoma have common genetic abnormalities, suggesting a relationship. A similar finding has been observed between papillary adenoma and papillary basophilic renal cancer. CONCLUSIONS: These findings suggest that molecular diagnostic testing will help determine histopathological diagnosis, identify tumor types with similar genetic abnormalities suggesting a common origin and indicate potential prognostic markers for future study.
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Cites
CpG-rich islands and the function of DNA methylation
Bird, A. P. (1986) · Nature · doi:10.1038/321209a0 · Cited by 3,777
Mutations of the VHL tumour suppressor gene in renal carcinoma
Gnarra, J. R., Tory, K., Weng, Y., Schmidt, L., Wei, M. H., Li, H., Latif, F., Liu, S., Chen, F., Duh, F.-M., et al. (1994) · Nature Genetics · doi:10.1038/ng0594-85 · Cited by 1,730
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Cited by
Rini, B. I., Campbell, S. C., & Escudier, B. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60229-4 · Cited by 1,621
Rini, B. I., Campbell, S. C., & Rathmell, W. K. (2006) · Current Opinion in Oncology · doi:10.1097/01.cco.0000219260.60714.c4 · Cited by 379
Expression Profiling of Renal Epithelial Neoplasms
Young, A. N., Amin, M. B., Moreno, C. S., Lim, S. D., Cohen, C., Petros, J. A., Marshall, F. F., & Neish, A. S. (2001) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64120-x · Cited by 311
Beck, S. D. W., Patel, M. I., Snyder, M. E., Kattan, M. W., Motzer, R. J., Reuter, V. E., & Russo, P. (2004) · Annals of Surgical Oncology · doi:10.1007/bf02524349 · Cited by 279
Wnt Signaling in Renal Cell Carcinoma
Xu, Q., Krause, M., Samoylenko, A., & Vainio, S. (2016) · Cancers · doi:10.3390/cancers8060057 · Cited by 99
Metadata
- Authors
- ZAMBRANO, N. R., LUBENSKY, I. A., MERINO, M. J., LINEHAN, W. M., & WALTHER, M. M.
- Venue
- Journal of Urology
- Published
- 1999-10
- Volume
- 162
- Issue
- 4
- Pages
- 1246-1258
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2077517865
- Cited by
- 167
- References
- 2
- FWCI
- 10.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEM. https://app.cochat.ai/papers/10.1016/s0022-5347(05)68259-6
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- ZAMBRANO, N. R., LUBENSKY, I. A., MERINO, M. J., LINEHAN, W. M., & WALTHER, M. M. (1999). HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEM. Journal of Urology. https://doi.org/10.1016/s0022-5347(05)68259-6
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