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Cited by 167

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEM

ZAMBRANO, NORMAN R., LUBENSKY, IRINA A., MERINO, MARIA J., LINEHAN, W. MARSTON, WALTHER, McCLELLAN M.·1999·Journal of Urology

Abstract

PURPOSE: We characterize the genetic abnormalities associated with pathological subtypes of renal tumors, which may help diagnosis or prognostication. MATERIALS AND METHODS: A comprehensive literature review of genetic abnormalities associated with different renal tumor subtypes was performed. RESULTS: Studies of sporadic and hereditary forms suggest that abnormalities in the von Hippel-Lindau and met genes are the earliest changes in conventional (clear cell) and papillary basophilic renal cancers, respectively. Renal oncocytoma and chromophobe carcinoma have common genetic abnormalities, suggesting a relationship. A similar finding has been observed between papillary adenoma and papillary basophilic renal cancer. CONCLUSIONS: These findings suggest that molecular diagnostic testing will help determine histopathological diagnosis, identify tumor types with similar genetic abnormalities suggesting a common origin and indicate potential prognostic markers for future study.

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Metadata

Authors
ZAMBRANO, N. R., LUBENSKY, I. A., MERINO, M. J., LINEHAN, W. M., & WALTHER, M. M.
Venue
Journal of Urology
Published
1999-10
Volume
162
Issue
4
Pages
1246-1258
ISSN
  • 0022-5347 (ISSN-L)
  • 1527-3792
OpenAlex
W2077517865
Cited by
167
References
2
FWCI
10.68
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEM. https://app.cochat.ai/papers/10.1016/s0022-5347(05)68259-6
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ZAMBRANO, N. R., LUBENSKY, I. A., MERINO, M. J., LINEHAN, W. M., & WALTHER, M. M. (1999). HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEM. Journal of Urology. https://doi.org/10.1016/s0022-5347(05)68259-6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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