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Cited by 261

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Radical Prostatectomy for Clinical Stage T1-2N0M0 Prostatic Adenocarcinoma: Long-Term Results

Paulson, David F., Moul, Judd W., Walther, Philip J.·1990·Journal of Urology

Abstract

A total of 441 stage T1-2N0M0 and 11 stage T1-2N0M0 cancer patients with an elevated acid phosphatase level only, and 18 stage T1-2N+M0 cancer patients underwent radical prostatectomy. Analysis of the 441 stage T1-2N0M0 cancer patients demonstrated that failure and survival were a function of the disease being organ-confined, specimen-confined or margin-positive, with 10-year failure rates of 12, 30 and 60%, respectively. Of the patients with positive margins 44 were and 79 were not irradiated postoperatively. Postoperative radiation produced no survival advantage. No difference in interval to failure or of survival could be identified between 105 patients whose disease was diagnosed by transurethral resection and 328 who had a palpable abnormality. Eleven patients had negative bone and node findings but they had an elevated acid phosphatase level. All 8 patients not treated with immediate androgen deprivation failed within 36 months.

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Metadata

Authors
Paulson, D. F., Moul, J. W., & Walther, P. J.
Venue
Journal of Urology
Published
1990-11
Volume
144
Issue
5
Pages
1180-1184
ISSN
  • 0022-5347 (ISSN-L)
  • 1527-3792
OpenAlex
W2406502491
Cited by
261
References
0
FWCI
16.42
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Radical Prostatectomy for Clinical Stage T1-2N0M0 Prostatic Adenocarcinoma: Long-Term Results. https://app.cochat.ai/papers/10.1016/s0022-5347(17)39686-6
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Paulson, D. F., Moul, J. W., & Walther, P. J. (1990). Radical Prostatectomy for Clinical Stage T1-2N0M0 Prostatic Adenocarcinoma: Long-Term Results. Journal of Urology. https://doi.org/10.1016/s0022-5347(17)39686-6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.