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Testicular Cancer Risk in Boys With Maldescended Testis: A Cohort Study
Abstract
Testicular maldescent is considered as a predisposing condition for development of testicular malignancy. Male subjects with a history of cryptorchidism have been suggested by some authors to have a 40 to 50 times increased risk of testis cancer. However, the magnitude of this risk is a point of considerable disagreement. Therefore, we studied the records of 506 consecutive patients hospitalized for maldescended testis from January 1949 to December 1960. Testis cancer developed in 6 patients, which when compared to the 1.3 expectant Danish incidence rate, yielded a statistically significant relative risk of 4.7 (95 per cent confidence interval 1.7 to 10.2). Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
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Cited by
Malmberg, K. (1997) · BMJ · doi:10.1136/bmj.314.7093.1512 · Cited by 1,286
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Adami, H., Bergström, R., Möhner, M., Zatoôski, W., Storm, H., Ekbom, A., Tretli, S., Teppo, L., Ziegler, H., Rahu, M., et al. (1994) · International Journal of Cancer · doi:10.1002/ijc.2910590108 · Cited by 473
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Metadata
- Authors
- Giwercman, A., Grindsted, J., Hansen, B., Jensen, O. M., & Skakkebaek, N. E.
- Venue
- Journal of Urology
- Published
- 1987-11
- Volume
- 138
- Issue
- 5
- Pages
- 1214-1216
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2400782524
- Cited by
- 186
- References
- 0
- FWCI
- 3.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Testicular Cancer Risk in Boys With Maldescended Testis: A Cohort Study. https://app.cochat.ai/papers/10.1016/s0022-5347(17)43553-1
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- Giwercman, A., Grindsted, J., Hansen, B., Jensen, O. M., & Skakkebaek, N. E. (1987). Testicular Cancer Risk in Boys With Maldescended Testis: A Cohort Study. Journal of Urology. https://doi.org/10.1016/s0022-5347(17)43553-1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
