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Intracavitary Bacillus Calmette-guerin in the Treatment of Superficial Bladder Tumors

Morales, A., Eidinger, D., Bruce, A.W.·1976·Journal of Urology

Abstract

No AccessJournal of Urology1 Aug 1976Intracavitary Bacillus Calmette-guerin in the Treatment of Superficial Bladder Tumors A. Morales, D. Eidinger, and A.W. Bruce A. MoralesA. Morales Current address: Laboratory of Immunodiagnosis, Building 8, Room 118, National Institutes of Health, Bethesda, Maryland, 20014. More articles by this author , D. EidingerD. Eidinger More articles by this author , and A.W. BruceA.W. Bruce More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)58737-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Patients with recurrent superficial bladder tumors have been treated by vesical and intradermal administration of Bacillus Calmette-Guerin. The pattern of recurrence in 9 patients has been altered favorably. Although the findings are still preliminary they appear to hold promise of a new therapeutic approach to the treatment of a group of neoplasms for which effective therapy is still lacking. © 1976 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byDonin N, Lenis A, Holden S, Drakaki A, Pantuck A, Belldegrun A and Chamie K (2018) Immunotherapy for the Treatment of Urothelial CarcinomaJournal of Urology, VOL. 197, NO. 1, (14-22), Online publication date: 1-Jan-2017.Droller M (2016) Intracavitary bacillus Calmette-Guérin for Superficial Bladder TumorsJournal of Urology, VOL. 197, NO. 2S, (S146-S147), Online publication date: 1-Feb-2017.Yokomizo A, Kanimoto Y, Okamura T, Ozono S, Koga H, Iwamura M, Tanaka H, Takahashi S, Tsushima T, Kanayama H, Akaza H, Shinohara N, Mugiya S, Nomata K, Nakamura T and Naito S (2018) Randomized Controlled Study of the Efficacy, Safety and Quality of Life with Low Dose bacillus Calmette-Guérin Instillation Therapy for Nonmuscle Invasive Bladder CancerJournal of Urology, VOL. 195, NO. 1, (41-46), Online publication date: 1-Jan-2016.Gan C, Amery S, Chatterton K, Khan M, Thomas K and O’Brien T (2018) Sequential bacillus Calmette-Guérin/Electromotive Drug Administration of Mitomycin C as the Standard Intravesical Regimen in High Risk Nonmuscle Invasive Bladder Cancer: 2-Year OutcomesJournal of Urology, VOL. 195, NO. 6, (1697-1703), Online publication date: 1-Jun-2016.Holmäng S (2018) Patients with High Grade Bladder Cancer, and Tumor-Free 3 and 6-Month Cystoscopy after bacillus Calmette-Guérin have a Good Prognosis without Further Maintenance bacillus Calmette-GuérinUrology Practice, VOL. 3, NO. 1, (50-54), Online publication date: 1-Jan-2016.Barlow L, McKiernan J and Benson M (2018) Long-Term Survival Outcomes with Intravesical Docetaxel for Recurrent Nonmuscle Invasive Bladder Cancer After Previous Bacillus Calmette-Guérin TherapyJournal of Urology, VOL. 189, NO. 3, (834-839), Online publication date: 1-Mar-2013.Johnson M, Nepple K, Peck V, Trinkaus K, Klim A, Sandhu G and Kibel A (2018) Randomized Controlled Trial of Oxybutynin Extended Release Versus Placebo for Urinary Symptoms During Intravesical Bacillus Calmette-Guérin TreatmentJournal of Urology, VOL. 189, NO. 4, (1268-1274), Online publication date: 1-Apr-2013.Brausi M, Witjes J, Lamm D, Persad R, Palou J, Colombel M, Buckley R, Soloway M, Akaza H and Böhle A (2018) A Review of Current Guidelines and Best Practice Recommendations for the Management of Nonmuscle Invasive Bladder Cancer by the International Bladder Cancer GroupJournal of Urology, VOL. 186, NO. 6, (2158-2167), Online publication date: 1-Dec-2011.Alvarez-Múgica M, Cebrian V, Fernández-Gómez J, Fresno F, Escaf S and Sánchez-Carbayo M (2018) Myopodin Methylation is Associated With Clinical Outcome in Patients With T1G3 Bladder CancerJournal of Urology, VOL. 184, NO. 4, (1507-1513), Online publication date: 1-Oct-2010.DeCastro G and Steinberg G (2018) Are We Making Significant Progress in the Diagnosis and Management of Bladder Cancer?Journal of Urology, VOL. 183, NO. 5, (1667-1668), Online publication date: 1-May-2010.Nepple K, Lightfoot A, Rosevear H, O'Donnell M and Lamm D (2018) Bacillus Calmette-Guérin With or Without Interferon α-2b and Megadose Versus Recommended Daily Allowance Vitamins During Induction and Maintenance Intravesical Treatment of Nonmuscle Invasive Bladder CancerJournal of Urology, VOL. 184, NO. 5, (1915-1919), Online publication date: 1-Nov-2010.Rosevear H, Lightfoot A, Nepple K and O'Donnell M (2018) Safety and Efficacy of Intravesical Bacillus Calmette-Guérin Plus Interferon α-2b Therapy for Nonmuscle Invasive Bladder Cancer in Patients With Prosthetic DevicesJournal of Urology, VOL. 184, NO. 5, (1920-1924), Online publication date: 1-Nov-2010.Bisiaux A, Thiounn N, Timsit M, Eladaoui A, Chang H, Mapes J, Mogenet A, Bresson J, Prié D, Béchet S, Baron C, Sadorge C, Thomas S, Albert E, Albert P and Albert M (2018) Molecular Analyte Profiling of the Early Events and Tissue Conditioning Following Intravesical Bacillus Calmette-Guerin Therapy in Patients With

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Research works printed but not linked: 17

  1. Veenema, 1969, Thiotepa bladder instillations: therapy and prophylaxis for superficial bladder tumors, J. Urol., 101, 711, 10.1016/S0022-5347(17)62408-X · doi:10.1016/s0022-5347(17)62408-x
  2. Riddle, 1973, The management of superficial bladder tumours with intravesical epodyl, Brit. J. Urol., 45, 84, 10.1111/j.1464-410X.1973.tb00048.x · doi:10.1111/j.1464-410x.1973.tb00048.x
  3. Durrant, 1975, Treatment of multiple superficial papillary tumors of the bladder by intracavitary yttrium-90, J. Urol., 113, 480, 10.1016/S0022-5347(17)59505-1 · doi:10.1016/s0022-5347(17)59505-1
  4. Bubenik, 1970, Immune response to urinary bladder tumours in man, Int. J. Cancer, 5, 39, 10.1002/ijc.2910050106 · doi:10.1002/ijc.2910050106
  5. Catalona, 1973, Correlation among host immunocompetence and tumor stage, tumor grade and vascular permeation in transitional carcinoma, J. Urol., 110, 526, 10.1016/S0022-5347(17)60270-2 · doi:10.1016/s0022-5347(17)60270-2
  6. Zbar, 1974, Immunotherapy of guinea pig cancer with BCG, Cancer, 34, 1532, 10.1002/1097-0142(197410)34:8+<1532::AID-CNCR2820340827>3.0.CO;2-H · DOI
  7. Jondal, 1973, Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells, J. Exp. Med., 136, 207, 10.1084/jem.136.2.207 · doi:10.1084/jem.136.2.207
  8. Ferluga, 1973, Increased cytolytic activity of a subcellular fraction from mouse liver after B.C.G. injection, Lancet, 2, 1476, 10.1016/S0140-6736(73)92734-7 · DOI
  9. Gutterman, 1973, BCG stimulation of immune responsiveness in patients with malignant melanoma, Cancer, 32, 321, 10.1002/1097-0142(197308)32:2<321::AID-CNCR2820320207>3.0.CO;2-Y · doi:10.1002/1097-0142(197308)32:2<321::aid-cncr2820320207>3.0.co;2-y
  10. Grant, 1974, Results of administering B.C.G. to patients with melanoma, Lancet, 2, 1096, 10.1016/S0140-6736(74)90867-8 · doi:10.1016/s0140-6736(74)90867-8
  11. Donaldson, 1973, Chemoimmunotherapy for cancer of the head and neck, Amer. J. Surg., 126, 507, 10.1016/S0002-9610(73)80040-6 · doi:10.1016/s0002-9610(73)80040-6
  12. Morales, 1976, Bacillus Calmette-Guerin in the treatment of adenocarcinoma of the kidney, J. Urol., 115, 377, 10.1016/S0022-5347(17)59210-1 · doi:10.1016/s0022-5347(17)59210-1
  13. Bloomberg, 1975, The effects of BCG on the dog bladder, Invest. Urol., 12, 423
  14. Hanna, 1972, Histopathology of Mycobacterium bovis (BCG)-mediated tumor regression, Nat. Cancer Inst. Monogr., 35, 345
  15. Falk, 1973, Cell-mediated immunity to human tumors. Abrogation by serum factors and nonspecific effects of oral BCG therapy, Arch. Surg., 107, 261, 10.1001/archsurg.1973.01350200123026 · doi:10.1001/archsurg.1973.01350200123026
  16. Morales, 1976, Immune reactivity in renal cancer: a sequential study, J. Urol., 115, 510, 10.1016/S0022-5347(17)59261-7 · doi:10.1016/s0022-5347(17)59261-7
  17. Papatestas, 1974, Peripheral lymphocyte counts in breast carcinoma. An index of immune competence, Cancer, 34, 2014, 10.1002/1097-0142(197412)34:6<2014::AID-CNCR2820340620>3.0.CO;2-Q · doi:10.1002/1097-0142(197412)34:6<2014::aid-cncr2820340620>3.0.co;2-q

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Metadata

Authors
Morales, A., Eidinger, D., & Bruce, A. W.
Venue
Journal of Urology
Published
1976-08
Volume
116
Issue
2
Pages
180-182
ISSN
  • 0022-5347 (ISSN-L)
  • 1527-3792
OpenAlex
W4243650202
Cited by
1,791
References
0
FWCI
7.69
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Intracavitary Bacillus Calmette-guerin in the Treatment of Superficial Bladder Tumors. https://app.cochat.ai/papers/10.1016/s0022-5347(17)58737-6
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Morales, A., Eidinger, D., & Bruce, A. W. (1976). Intracavitary Bacillus Calmette-guerin in the Treatment of Superficial Bladder Tumors. Journal of Urology. https://doi.org/10.1016/s0022-5347(17)58737-6

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