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Assessing and Managing All Aspects of Migraine: Migraine Attacks, Migraine-Related Functional Impairment, Common Comorbidities, and Quality of Life
Open accessAbstract
Migraine can be characterized as a chronic disorder with episodic attacks and the potential for progression to chronic migraine. We conducted a PubMed literature search (January 1, 1970 through May 31, 2008) for studies on the impact of migraine, including disability, health-related quality of life (HRQoL), comorbidities, and instruments used by health care professionals to treat patients with migraine. Numerous studies have shown that migraine substantially impairs a person's functions during attacks and diminishes HRQoL during and between attacks. Despite its impact, migraine remains underestimated, underdiagnosed, and undertreated. Several tools are available to help physicians assess the impact of migraine on the daily activities and HRQoL of their patients, such as the 36-Item Short-Form Health Survey and the Headache Impact Test. Improving communication during the office visit through active listening, use of open-ended questions, and use of the "ask-tell-ask" strategy can also help in assessing migraine-related impairment. Together, these tools and communication techniques can lead to a more complete assessment of how migraine affects patients' lives and can aid in the development of the optimal treatment plan for each patient. Both pharmacotherapy (acute and preventive treatment strategies) and nonpharmacological therapies play important roles in the management of migraine.
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“Yet, despite its deleterious impact, depression in migraineurs is underdiagnosed and undertreated [6].”
From One-Day Acceptance and Commitment Therapy Compared to Support for Depressed Migraine Patients: a Randomized Clinical Trial. (2020) · cites this paper as [6]
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Existential concerns and fear of recurrence or progression in people with migraine
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Piella, E. M., Chiarandon, A. M., Albanese, M., Puddu, E. M., Pistoia, F., Saporito, G., Altieri, M., Giuliani, G., Vaghi, G., Sances, G., et al. (2026) · Neurological Sciences · doi:10.1007/s10072-026-09029-w
Metadata
- Authors
- Buse, D. C., Rupnow, M. F. T., & Lipton, R. B.
- Affiliations
- Albert Einstein College of Medicine (US)
- Janssen Scientific Affairs (United States) (US)
- Corresponding author
- Buse, Dawn C.
- Venue
- Mayo Clinic Proceedings
- Publisher
- Elsevier BV
- Published
- 2009-05
- Volume
- 84
- Issue
- 5
- Pages
- 422-435
- ISSN
- 0025-6196 (ISSN-L)
- PMC
- PMC2676125
- OpenAlex
- W2112004018
- Cited by
- 318
- References
- 141
- Citations by year
- 2026: 33 · 2025: 23 · 2024: 30 · 2023: 31 · 2022: 22 · 2021: 29 · 2020: 23 · 2019: 20 · 2018: 19 · 2017: 6 · 2016: 10 · 2015: 15 · 2014: 10 · 2013: 14 · 2012: 15
- FWCI
- 1.34
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Mayo Clinic Proceedings (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- AstraZeneca
- Allergan
- Topics
- Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
- Keywords
- migraine, health-related quality of life, migraine comorbidity, chronic migraine, migraine underdiagnosis, Headache Impact Test, SF-36, physician-patient communication, acute migraine treatment, migraine prophylaxis
- MeSH terms
- Chronic Disease, Disability Evaluation, Humans, Migraine Disorders, Quality of Life, Surveys and Questionnaires, Comorbidity, Disease Progression
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