The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Accommodating Protein Flexibility in Computational Drug Design,
Abstract
The need to account for the dynamic behavior of a receptor has long been recognized as a complicating factor in computational drug design. The use of a single, rigid protein structure—usually from a high-quality X-ray crystal structure—still is the standard in most applications ([Zheng and Kyle
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Citations
Cites
Folding funnels and binding mechanisms
Ma, B., Kumar, S., Tsai, C.-J., & Nussinov, R. (1999) · Protein Engineering, Design and Selection · doi:10.1093/protein/12.9.713 · Cited by 594
Cited by
Principles of docking: An overview of search algorithms and a guide to scoring functions
Halperin, I., Ma, B., Wolfson, H., & Nussinov, R. (2002) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.10115 · Cited by 1,294
The Process of Structure-Based Drug Design
Anderson, A. C. (2003) · Chemistry & Biology · doi:10.1016/j.chembiol.2003.09.002 · Cited by 939
Calculation of absolute protein–ligand binding free energy from computer simulations
Woo, H.-J., & Roux, B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409005102 · Cited by 661
Multiple diverse ligands binding at a single protein site: A matter of pre‐existing populations
Ma, B., Shatsky, M., Wolfson, H. J., & Nussinov, R. (2002) · Protein Science · doi:10.1110/ps.21302 · Cited by 420
Computational Drug Design Accommodating Receptor Flexibility: The Relaxed Complex Scheme
Lin, J.-H., Perryman, A. L., Schames, J. R., & McCammon, J. A. (2002) · Journal of the American Chemical Society · doi:10.1021/ja0260162 · Cited by 386
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Metadata
- Authors
- Carlson, H. A., & McCammon, J. A.
- Venue
- Molecular Pharmacology
- Publisher
- Elsevier BV
- Published
- 2000-02
- Volume
- 57
- Issue
- 2
- Pages
- 213-218
- ISSN
- 0026-895X (ISSN-L)
- OpenAlex
- W1874531505
- Cited by
- 324
- References
- 1
- FWCI
- 18.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Carlson, H. A., & McCammon, J. A. (2000). Accommodating Protein Flexibility in Computational Drug Design,. Molecular Pharmacology. https://doi.org/10.1016/s0026-895x(24)23192-8
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
