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Syntheses and application of polylactides
Abstract
Polylactides can be prepared by direct polycondensation of lactic acid, or better, by ring-opening polymerization of cyclic dilactides (usually called lactides). These lactides exist in the form of four stereoisomers two of which (L,L- and rac. -D,L-) are technically produced in large quantities. These lactides can by polymerized via four different classes of initiators and reaction mechanisms. The characteristics mechanistic and preparative features of the cationic polymerization, anionic polymerization and of the coordination-insertion mechanism are described. Furthermore, copolymerizations of lactides with glycolide or epsilon-caprolactone and their analytical problems are discussed. Finally, a new type of wound dressing based on transparent are resorbable films of copolylactides is mentioned.
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From Iron( ii ) carboxylates and simple carboxamides: an inexpensive and modular catalyst system for the synthesis of PLLA and PLLA-PCL block copolymers (2023) · cites this paper as [34]
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Metadata
- Authors
- Kricheldorf, H. R.
- Affiliations
- Universität Hamburg (DE)
- Corresponding author
- Kricheldorf, Hans R
- ORCID
- Kricheldorf, Hans R
- Venue
- Chemosphere
- Publisher
- Elsevier BV
- Published
- 2001-04
- Volume
- 43
- Issue
- 1
- Pages
- 49-54
- ISSN
- 0045-6535 (ISSN-L)
- OpenAlex
- W1995595540
- Cited by
- 343
- References
- 25
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 5 · 2023: 9 · 2022: 9 · 2021: 17 · 2020: 8 · 2019: 11 · 2018: 9 · 2017: 16 · 2016: 15 · 2015: 12 · 2014: 18 · 2013: 23 · 2012: 26
- FWCI
- 5.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemosphere (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer crystallization and properties
- Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
- Keywords
- polylactic acid, lactide ring-opening polymerization, stereoisomers, cationic polymerization, anionic polymerization, coordination-insertion mechanism, wound dressings, biodegradable polymers
- MeSH terms
- Bandages, Biocompatible Materials, Humans, Polyesters, Polymers
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