Possible association of Alzheimer’s disease with HLA-BW15 and cytomegalovirus infection
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In one of the first studies analyzing an association between HLA haplotype and AD, HLA-BW15+ AD patients had significantly higher CMV antibody titers than those that were HLA-BW15−.
“For CMV, in one of the first studies analyzing an association between HLA haplotype and AD, HLA-BW15+ AD patients had significantly higher CMV antibody titers than those that were HLA-BW15− [50].”
From What would it take to prove that a chronic infection is a causal agent in Alzheimer’s disease? (2025) · cites this paper as [50]
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Time to test antibacterial therapy in Alzheimer’s disease
Panza, F., Lozupone, M., Solfrizzi, V., Watling, M., & Imbimbo, B. P. (2019) · Brain · doi:10.1093/brain/awz244 · Cited by 161 · see citing works
What would it take to prove that a chronic infection is a causal agent in Alzheimer’s disease?
Brutkiewicz, R. R., Cao, W., Morgan, D., Reis, R. S. D., Suryadevara, V., Willette, A. A., Willette, S. A., Wyatt-Johnson, S. K., & Duggan, M. R. (2025) · Trends in Neurosciences · doi:10.1016/j.tins.2025.05.009 · Cited by 3 · see citing works
- Authors
- Renvoize, E. B., Hambling, M. H., Pepper, M. D., & Rajah, S. M.
- Affiliations
- University of Leeds (GB)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1979-06
- Volume
- 313
- Issue
- 8128
- Pages
- 1238
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2018933802
- Cited by
- 31
- References
- 0
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 1 · 2019: 2 · 2018: 1
- FWCI
- 2.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Epidemiology › Cytomegalovirus and herpesvirus research
- Keywords
- Alzheimer's disease, cytomegalovirus infection, HLA class I association, viral infection, genetic susceptibility
- MeSH terms
- Aged, Alzheimer Disease, Antibodies, Viral, Cytomegalovirus, Dementia, Female, HLA Antigens, Humans, Male, Middle Aged
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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