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Cited by 202

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EPITHELIOID HAEMANGIOMA-LIKE VASCULAR PROLIFERATION IN AIDS: MANIFESTATION OF CAT SCRATCH DISEASE BACILLUS INFECTION?

Open access
Leboit, PhilipE., Egbert, BarbaraM., Stoler, MarkH., Strauchen, JamesA., Berger, TimothyG., Yen, T.S.Benedict, Bonfiglio, ThomasA., English, CharlesK., Wear, DouglasJ.·1988·The Lancet

Abstract

Papular and nodular skin lesions that clinically resembled Kaposi sarcoma, but histologically showed a distinct epithelioid haemangioma-like appearance, were noted in seven patients with the acquired immunodeficiency syndrome. Clusters of bacteria that had the structure of gram-negative rods were identified within each of the vascular proliferations by electron microscopy. The bacteria did not stain with the Brown-Brenn, acid-fast, or other histochemical stains for infectious organisms, but did stain with Warthin-Starry--ie, the staining profile was that described for the cat scratch disease (CSD) bacillus. Immunoperoxidase staining, using antisera raised in rabbits against cultured CSD bacillus, showed a positive reaction with the bacterium in all five cases tested. The two surviving patients have both given histories of having been scratched by a cat. In several patients, the vascular lesions regressed after therapy with antibiotics appropriate for CSD bacillus infection.

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Metadata

Authors
Leboit, P., Egbert, B., Stoler, M., Strauchen, J., Berger, T., Yen, T. S. B., Bonfiglio, T., English, C., & Wear, D.
Venue
The Lancet
Publisher
Elsevier BV
Published
1988-04
Volume
331
Issue
8592
Pages
960-963
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W1976314161
Cited by
202
References
0
FWCI
17.59
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: EPITHELIOID HAEMANGIOMA-LIKE VASCULAR PROLIFERATION IN AIDS: MANIFESTATION OF CAT SCRATCH DISEASE BACILLUS INFECTION? https://app.cochat.ai/papers/10.1016/s0140-6736(88)91779-5
The paper
Leboit, P., Egbert, B., Stoler, M., Strauchen, J., Berger, T., Yen, T. S. B., Bonfiglio, T., English, C., & Wear, D. (1988). EPITHELIOID HAEMANGIOMA-LIKE VASCULAR PROLIFERATION IN AIDS: MANIFESTATION OF CAT SCRATCH DISEASE BACILLUS INFECTION? The Lancet. https://doi.org/10.1016/s0140-6736(88)91779-5

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.