NORMAL AGEING, IMPAIRED COGNITIVE FUNCTION, AND SENILE DEMENTIA OF THE ALZHEIMER'S TYPE: A CONTINUUM?
Abstract
There is little evidence to support the view that senile dementia of the Alzheimer's type (SDAT) is distinct from the normal ageing process. The changes in brain function found in normal ageing, benign senescent forgetfulness, and SDAT can be seen as a continuum, which may reflect a single underlying process. The failure to account for this possibility in research design may explain why few risk factors for SDAT have been identified.
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- Authors
- Brayne, C., & Calloway, P.
- Affiliations
- Addenbrooke's Hospital (GB)
- Fulbourn Hospital (GB)
- ORCID
- Brayne, Carol
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1988-06
- Volume
- 331
- Issue
- 8597
- Pages
- 1265-1267
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2066896247
- Cited by
- 209
- References
- 36
- Citations by year
- 2024: 2 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 4 · 2015: 4 · 2014: 3 · 2013: 4 · 2012: 11
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
- Keywords
- normal aging, Alzheimer's disease, cognitive impairment, risk factors, brain function changes
- MeSH terms
- Age Factors, Aged, Aging, Alzheimer Disease, Cognition Disorders, Dementia, Female, Humans, Interview, Psychological, Memory Disorders, Risk Factors, Sampling Studies
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