EARLY MARKER FOR ALZHEIMER'S DISEASE: THE ATROPHIC HIPPOCAMPUS

Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915

The Global Deterioration Scale for assessment of primary degenerative dementia

Reisberg, ‌., Ferris, S. H., de Leon, M. J., & Crook, T. H. (1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.9.1136 · Cited by 5,122

The prevalence of dementia: A quantitative integration of the literature

Jorm, A. F., Korten, A. E., & Henderson, A. S. (1987) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1987.tb02906.x · Cited by 1,301

Perforant pathway changes and the memory impairment of Alzheimer's disease

Hyman, B. T., Van Hoesen, G. W., Kromer, L. J., & Damasio, A. R. (1986) · Annals of Neurology · doi:10.1002/ana.410200406 · Cited by 672

A NEW DEFINITION OF ALZHEIMER'S DISEASE: A HIPPOCAMPAL DEMENTIA

Ball, M. J., Hachinski, V., Fox, A. J., Kirshen, A. J., Fisman, M., Blume, W. T., Kral, V. A., Fox, H., & Merskey, H. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90965-1 · Cited by 427

ABNORMAL CORTISOL RESPONSE IN ALZHEIMER'S DISEASE LINKED TO HIPPOCAMPAL ATROPHY

de Leon, M. J., McRae, T., Tsai, J., GEORGE, A. E., MARCUS, D., Freedman, M. S., Wolf, A., & McEwen, B. S. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92855-3 · Cited by 198

CT diagnostic features of Alzheimer disease: importance of the choroidal/hippocampal fissure complex.

GEORGE, A. E., de Leon, M. J., Stylopoulos, L. A., Miller, J. D., Kluger, A., Smith, G. S., & Miller, D. C. (1990) · PubMed Central · Cited by 115

Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production

Rice, R. A., Berchtold, N. C., Cotman, C. W., & Green, K. N. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.10.090 · Cited by 57

EEG-based classification of Alzheimer’s disease and frontotemporal dementia: a comprehensive analysis of discriminative features

Rostamikia, M., Sarbaz, Y., & Makouei, S. (2024) · Cognitive Neurodynamics · doi:10.1007/s11571-024-10152-7 · Cited by 62

A neurocomputational model of classical conditioning phenomena: A putative role for the hippocampal region in associative learning

Moustafa, A. A., Myers, C. E., & Gluck, M. A. (2009) · Brain Research · doi:10.1016/j.brainres.2009.04.020 · Cited by 56

Imaging of Alzheimer's Disease

Lee, B. C. P., Mintun, M. A., Buckner, R. L., & Morris, J. C. (2003) · Journal of Neuroimaging · doi:10.1111/j.1552-6569.2003.tb00179.x · Cited by 55

Hippocampal sulcus width and cavities: comparison between patients with Alzheimer disease and nondemented elderly subjects.

de Bastos-Leite, A. J., van Waesberghe, J. H., Oen, A. L., van der Flier, W. M., Scheltens, P., & Barkhof, F. (2006) · PubMed Central · Cited by 55

Prolongation of magnetic resonance T2 time in hippocampus of human patients marks the presence and severity of Alzheimer's disease

Kirsch, S. J., Jacobs, R. W., Butcher, L. L., & Beatty, J. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90513-7 · Cited by 54

Metabolic brain mapping in Alzheimer's disease using proton magnetic resonance spectroscopy.

Lazeyras, F., Charles, H., Tupler, L., Erickson, R., Boyko, O., & Krishnan, K. (1998) · Psychiatry Research · doi:10.1016/s0925-4927(98)00010-9 · Cited by 52

A neural model of hippocampal–striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients

Moustafa, A. A., Kéri, S., Herzallah, M. M., Myers, C. E., & Gluck, M. A. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2010.07.013 · Cited by 51

Inexpensive, non-invasive biomarkers predict Alzheimer transition using machine learning analysis of the Alzheimer’s Disease Neuroimaging (ADNI) database

Beltrán, J. F., Wahba, B. M., Hose, N., Shasha, D. E., Kline, R., & Initiative, A. D. N. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235663 · Cited by 50

Hippocampal Atrophy in Persons With Age-Associated Memory Impairment: Volumetry Within a Common Space

Mega, M. S., Small, G. W., Xu, M. L., Felix, J., Manese, M., Tran, N. P., Dailey, J. I., Ercoli, L. M., Bookheimer, S. Y., & Toga, A. W. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200205000-00013 · Cited by 50

Neuroimaging Results Impose New Views on Alzheimer’s Disease—the Role of Amyloid Revised

Fjell, A. M., & Walhovd, K. B. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8228-7 · Cited by 48

A novel method of quantifying brain atrophy associated with age-related hearing loss

Qian, Z. J., Chang, P. D., Moonis, G., & Lalwani, A. K. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.07.021 · Cited by 49

Magnetic resonance and PET studies in the early diagnosis of Alzheimer’s disease

Mosconi, L., De Santi, S., Rusinek, H., Convit, A., & de Leon, M. J. (2004) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.4.5.831 · Cited by 46

Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly

Oh, H., Steffener, J., Razlighi, Q. R., Habeck, C. G., Liu, D., Gazes, Y., Janicki, S. C., & Stern, Y. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.08.016 · Cited by 46

Applying surface-based hippocampal morphometry to study APOE-E4 allele dose effects in cognitively unimpaired subjects

Dong, Q., Zhang, W., Wu, J., Li, B., Schron, E. H., McMahon, T., Shi, J., Gutman, B. A., Chen, K., Baxter, L. C., et al. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101744 · Cited by 44

NEUROIMAGING IN DEMENTIA

Jagust, W. J. (2000) · Neurologic Clinics · doi:10.1016/s0733-8619(05)70231-0 · Cited by 41

Critical Issues for Successful Immunotherapy in Alzheimers Disease: Development of Biomarkers and Methods for Early Detection and Intervention

Tarawneh, R. M., & Holtzman, D. M. (2009) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152709787847324 · Cited by 43

Medial temporal lobe atrophy in memory disorders

Pasquier, F., le Hamon, M. X. E., Lebert, F., Jacob, B., Pruvo, J., & Petit, H. (1997) · Journal of Neurology · doi:10.1007/s004150050069 · Cited by 41

Functional magnetic resonance imaging of semantic memory as a presymptomatic biomarker of Alzheimer's disease risk

Sugarman, M. A., Woodard, J. L., Nielson, K. A., Seidenberg, M., Smith, J. C., Durgerian, S., & Rao, S. M. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.09.016 · Cited by 41

The Role of Quantitative Structural Imaging in the Early Diagnosis of Alzheimer's DiseaseQ4

Głodzik-Sobańska, L., Rusinek, H., Mosconi, L., Li, Y., Zhan, J., Santi, S. D., Convit, A. J., Rich, K. E., Bryś, M., & de Leon, M. J. (2005) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2005.09.004 · Cited by 40

Dementia is associated with medial temporal atrophy even after accounting for neuropathologies

Woodworth, D. C., Sheikh‐Bahaei, N., Scambray, K. A., Phelan, M. J., Perez-Rosendahl, M. A., Corrada, M. M., Kawas, C. H., Sajjadi, S. A., & Initiative, A. D. N. (2022) · Brain Communications · doi:10.1093/braincomms/fcac052 · Cited by 39

Measurement of medial temporal lobe atrophy in diagnosis of Alzheimer's disease

de Leon, M. J., Golomb, J. B., Convit, A. J., DeSanti, S., McRae, T. D., GEORGE, A. E., Jobst, K. A., & Smith, A. D. (1993) · The Lancet · doi:10.1016/0140-6736(93)92610-6 · Cited by 39

Duration of neurofibrillary changes in the hippocampal pyramidal neurons

Bobinski, M., Węgiel, J., Tarnawski, M. J., Bobinski, M., de Leon, M. J., Reisberg, ‌., Miller, D. C., & Wı́sniewski, H. M. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00441-7 · Cited by 38

The human-specificCASP4gene product contributes to Alzheimer-related synaptic and behavioural deficits

Kajiwara, Y., McKenzie, A. T., Dorr, N. P., Sosa, M. A. G., Elder, G. A., Schmeidler, J., Dickstein, D. L., Bozdagi, O., Zhang, B., & Buxbaum, J. D. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw265 · Cited by 39

MR approaches in neurodegenerative disorders

Blamire, A. M. (2018) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2018.11.001 · Cited by 37

Learning and Generalization Tasks Predict Short-Term Cognitive Outcome in Nondemented Elderly

Myers, C. E., Kluger, A., Golomb, J. B., Gluck, M. A., & Ferris, S. H. (2008) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988708316858 · Cited by 33

NEUROIMAGING OF THE AGING BRAIN

Ketonen, L. (1998) · Neurologic Clinics · doi:10.1016/s0733-8619(05)70082-7 · Cited by 37

A six-month longitudinal evaluation significantly improves accuracy of predicting incipient Alzheimer's disease in mild cognitive impairment

Mubeen, A. M., Asaei, A., Bachman, A. H., Sidtis, J. J., & Ardekani, B. A. (2017) · Journal of Neuroradiology · doi:10.1016/j.neurad.2017.05.008 · Cited by 35

Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease

Butler, T., Harvey, P., Deshpande, A., Tanzi, E. B., Li, Y., Tsui, W., Silver, C., Fischer, E., Wang, X., Chen, J., et al. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.01.014 · Cited by 34

Preliminary Results from an MRI/CT‐Based Database for Vascular Dementia and Alzheimer's Disease

Scheltens, P., & Kittner, B. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06411.x · Cited by 34

Diagnosis of Alzheimer's Disease

Reisberg, ‌., Burns, A. S., Brodaty, H., Eastwood, R., Rossor, M. N., Sartorius, N., & Winblad, B. G. (1997) · International Psychogeriatrics · doi:10.1017/s1041610297004675 · Cited by 36

Neuro-imaging in the diagnosis of Alzheimer's disease I. Computer tomography and magnetic resonance imaging

Scheltens, P., Weinstein, H. C., & Leys, D. (1992) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(92)90175-3 · Cited by 33

CSF biomarker pathology correlates with a medial temporo-parietal network affected by very mild to moderate Alzheimer's disease but not a fronto-striatal network affected by healthy aging

Fjell, A. M., Amlien, I. K., Westlye, L. T., Stenset, V. T. V., Fladby, T., Skinningsrud, A., Eilsertsen, D. E., Bjørnerud, A., & Walhovd, K. B. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.029 · Cited by 32

Hippocampal cerebrospinal fluid spaces on MR imaging: Relationship to aging and Alzheimer disease.

Li, Y., Li, J., Segal, S., Węgiel, J., Santi, S. D., Zhan, J., & de Leon, M. J. (2006) · PubMed Central · Cited by 30

Functional Imaging Patterns in Alzheimer's Disease Relationships to Neurobiologya

Jagust, W. J. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb34398.x · Cited by 30

Tracking the decline in cerebral glucose metabolism in persons and laboratory animals at genetic risk for Alzheimer's disease

Reiman, E. M., Caselli, R. J., Alexander, G. E., & Chen, K. (2001) · Clinical Neuroscience Research · doi:10.1016/s1566-2772(01)00006-8 · Cited by 28

Structural neuroimaging of Alzheimer’s disease and other dementias

Scheltens, P. (2001) · Aging Clinical and Experimental Research · doi:10.1007/bf03351478 · Cited by 29

Cerebral correlates of cognitive aging: Gray-white-matter differentiation in the medial temporal lobes, and fluid versus crystallized abilities

Raz, N., Millman, D., & Sarpel, G. (1990) · Psychobiology · doi:10.3758/bf03333096 · Cited by 29

Commentary on age-associated memory impairment, age-related cognitive decline and mild cognitive impairment

Ferris, S. H., & Kluger, A. (1996) · Aging Neuropsychology and Cognition · doi:10.1080/13825589608256620 · Cited by 30

Biomarkers for the early diagnosis of Alzheimer's disease

de Leon, M. J., & Klunk, W. E. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70357-x · Cited by 29

Increased morning salivary cortisol levels in older adults with nonamnestic and multidomain mild cognitive impairment

Venero, C., Mardomingo, C. D., Pereda-Pérez, I., García‐Herranz, S., Utrera, L., Valencia, A., & Peraita, H. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.07.007 · Cited by 28

Mammillary Bodies in Alzheimer’s Disease

Balogiannis, S., Mavroudis, I. A., Baloyannis, I. S., & Costa, V. (2015) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317515602548 · Cited by 29

Computational identification of key genes that may regulate gene expression reprogramming in Alzheimer’s patients

Potashkin, J. A., Bottero, V., Santiago, J. A., & Quinn, J. P. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222921 · Cited by 29

Clinical subgroups of the Alzheimer syndrome

Wallin, A., & Blennow, K. (1996) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1996.tb05872.x · Cited by 28

Hippocampus and Parahippocampal Gyrus Linear Measurements Based on Magnetic Resonance in Alzheimer’s Disease

Pucci, E., Belardinelli, N., Regnicolo, L., Nolfe, G., Signorino, M., Salvolini, U., & Angeleri, F. (1998) · European Neurology · doi:10.1159/000007893 · Cited by 27

The Relationship between Associative Learning, Transfer Generalization, and Homocysteine Levels in Mild Cognitive Impairment

Moustafa, A. A., Hewedi, D. H., Eissa, A. M., Myers, C. E., & Sadek, H. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046496 · Cited by 26

Cortico-hippocampal interaction and adaptive stimulus representation: A neurocomputational theory of associative learning and memory

Gluck, M. A., Myers, C. E., & Meeter, M. (2005) · Neural Networks · doi:10.1016/j.neunet.2005.08.003 · Cited by 25

Computational Models of the Hippocampal Region: Implications for Prediction of Risk for Alzheimers Disease in Non-demented Elderly

Gluck, M. A., Myers, C. E., Nicolle, M. M., & Johnson, S. C. (2006) · Current Alzheimer Research · doi:10.2174/156720506777632826 · Cited by 24

Low cortical iron and high entorhinal cortex volume promote cognitive functioning in the oldest-old

Bergen, J. M. G. V., Li, X., Quevenco, F. C., Gietl, A. F., Treyer, V., Leh, S. E., Meyer, R., Buck, A., Kaufmann, P. A., Nitsch, R. M., et al. (2017) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.12.014 · Cited by 23

Neuropsychological tests and [99mTc]-HM PAO SPECT in the diagnosis of Alzheimer's dementia

Villa, G., Cappa, A., Tavolozza, M., Gainotti, G., Giordano, A., Calcagni, M. L., & Rossi, G. (1995) · Journal of Neurology · doi:10.1007/bf00868390 · Cited by 24

Impacts of High Serum Total Cholesterol Level on Brain Functional Connectivity in Non-Demented Elderly

Zhang, T., Li, H., Zhang, J., Li, X., Qi, D., Wang, N., & Zhang, Z. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150810 · Cited by 23

The Radial Width of the Temporal Horn in Mild Cognitive Impairment

Frisoni, G. B., Rossi, R., & Beltramello, A. (2002) · Journal of Neuroimaging · doi:10.1111/j.1552-6569.2002.tb00143.x · Cited by 23

Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects

Schreiner, S. J., Liu, X., Gietl, A. F., Wyss, M., Steininger, S. C., Gruber, E., Treyer, V., Meier, I. B., Kälin, A. M., Leh, S. E., et al. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00240 · Cited by 21

Quasi-conformal statistical shape analysis of hippocampal surfaces for Alzheimer׳s disease analysis

Chan, H. L., Li, H., & Lui, L. M. (2015) · Neurocomputing · doi:10.1016/j.neucom.2015.10.047 · Cited by 23

Accelerated Brain Atrophy on Serial Computed Tomography

Zahid, A. B., Mikheev, A. V., Srivatsa, N., Babb, J. S., Samadani, U., & Rusinek, H. (2016) · Journal of Computer Assisted Tomography · doi:10.1097/rct.0000000000000435 · Cited by 22

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats

Zhao, H., Mao, J., Yuan, Y., Feng, J., Cheng, H., Fan, G., Zhang, Y., & Li, T. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00523 · Cited by 21

Neuroanatomic Substrates of Late-Life Mental Disorders

Narayan, M., Bremner, J. D., & Kumar, A. (1999) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/089198879901200303 · Cited by 20

Functional Magnetic Resonance Imaging in Aging and Dementia: Detection of Age-Related Cognitive Changes and Prediction of Cognitive Decline

Woodard, J. L., & Sugarman, M. A. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_159 · Cited by 20

Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification

Coluzzi, D., Bordin, V., Rivolta, M. W., Fortel, I., Zhan, L., Leow, A., & Baselli, G. (2025) · Bioengineering · doi:10.3390/bioengineering12010082 · Cited by 23

The Role of the Entorhinal Cortex in Extinction: Influences of Aging

Bevilaqua, L. R., Rossato, J. I., Bonini, J. S., Myskiw, J. D. C., Clarke, J. R., Monteiro, S. C., Lima, R. H., Medina, J. H., Cammarota, M., & Izquierdo, I. (2008) · Neural Plasticity · doi:10.1155/2008/595282 · Cited by 20

Episodic memory of APOE ε4 carriers is correlated with fractional anisotropy, but not cortical thickness, in the medial temporal lobe

Westlye, E. T., Hodneland, E., Haász, J., Espeseth, T., Lundervold, A., & Lundervold, A. J. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.06.072 · Cited by 20

Brain Mapping in Dementia

Mega, M. S., Thompson, P. M., Toga, A. W., & Cummings, J. L. (2000) · Elsevier eBooks · doi:10.1016/b978-012481460-8/50012-3 · Cited by 19

NSAIDs may protect against age-related brain atrophy

Bendlin, B. B. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00035 · Cited by 17

Linear width of the medial temporal lobe can discriminate Alzheimer’s disease from normal aging: the Sunnybrook Dementia Study

Gao, F., Black, S. E., Leibovitch, F. S., Callen, D. J., Rockel, C. P., & Szalai, J. P. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(03)00121-0 · Cited by 17

Characterizing the Regional Structural Difference of the Brain between Tau Transgenic (rTg4510) and Wild-Type Mice Using MRI

Xie, Z., Yang, D., Stephenson, D. T., Morton, D. G., Hicks, C. D., Brown, T. M., & Bocan, T. M. A. (2010) · Lecture notes in computer science · doi:10.1007/978-3-642-15705-9_38 · Cited by 16

20 Brain Imaging in the Evaluation of Putative Alzheimer’s Disease-Slowing, Risk-Reducing and Prevention Therapies

Reiman, E. M., & Langbaum, J. B. S. (2009) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195328875.003.0020 · Cited by 16

Mapping the Genetic-Imaging-Clinical Pathway with Applications to Alzheimer’s Disease

Yu, D., Wang, L., Kong, D., & Hongtu Zhu, B. (2022) · Journal of the American Statistical Association · doi:10.1080/01621459.2022.2087658 · Cited by 18

New Tools for the Study of Alzheimer’s Disease

Fjell, A. M., & Walhovd, K. B. (2011) · The Neuroscientist · doi:10.1177/1073858410392586 · Cited by 17

Decreased Immunosuppressive Effect of Cortisol on Natural Killer Cytotoxic Activity in Senile Dementia of the Alzheimer Type

Solerte, S. B., Cerutti, N., Severgnini, S., Rondanelli, M., Ferrari, E., & Fioravanti, M. (1998) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000017040 · Cited by 15

Quantitative Computed Tomography and Magnetic Resonance Imaging in Aging and Alzheimer's Disease; A Review

Smith, C. D. (1996) · Journal of Neuroimaging · doi:10.1111/jon19966144 · Cited by 15

The HPA Axis and Psychopathology: Cushing's Syndrome

Starkman, M. N. (1993) · Psychiatric Annals · doi:10.3928/0048-5713-19931201-09 · Cited by 14

Symptoms of Memory Loss as Predictors of Cognitive Impairment?

Archer, H. A., McFarlane, F. A., Frost, C. D., Cutler, D., Fox, N. C., & Rossor, M. N. (2007) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e318065bfc2 · Cited by 14

Medial Temporal Lobe Atrophy, Apolipoprotein Genotype, and Plasma Homocysteine in Sri Lankan Patients with Alzheimer's Disease

de Silva, H. A., Gunatilake, S. B., Johnston, C., Warden, D. R., & Smith, A. D. (2005) · Experimental Aging Research · doi:10.1080/03610730590948221 · Cited by 14

Neonatal Neurodegeneration in Alzheimer’s Disease Transgenic Mouse Model

Mazi, A. R., Arzuman, A. S., Gürel, B., Şahin, B., Tüzüner, M. B., Ozansoy, M., & Baykal, A. T. (2018) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-170049 · Cited by 13

Detecting Alzheimer’s disease by morphological MRI using hippocampal grading and cortical thickness

Eskildsen, S. F., Pierrick Coupé, A., Fonov, V., & Collins, D. L. (2014) · Cited by 13

Pharmacological Characterisation of Cortical γ-Aminobutyric Acid Type A (GABAA) Receptors in Two Wistar Rat Lines Selectively Bred for High and Low Anxiety-Related Behaviour

Hermann, B., Landgraf, R., Keck, M. E., Wigger, A., Morrow, A. L., Ströhle, A., Holsboer, F., & Rupprecht, R. (2000) · The World Journal of Biological Psychiatry · doi:10.3109/15622970009150581 · Cited by 13

Organising the language of Alzheimer's disease in light of biomarkers

Schneider, L. S. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70246-5 · Cited by 13

A quantitatively interpretable model for Alzheimer’s disease prediction using deep counterfactuals

Oh, K., Heo, D.-W., Mulyadi, A. W., Jung, W., Kang, E., Lee, K. H., & Suk, H. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121077 · Cited by 12

Imaging Alzheimer’s disease

Small, S. A. (2003) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-003-0021-1 · Cited by 12

Learning and Generalization in Healthy Aging

Krishna, R., Moustafa, A. A., Eby, L. A., Skeen, L. C., & Myers, C. E. (2012) · Cognitive and Behavioral Neurology · doi:10.1097/wnn.0b013e318248ff1b · Cited by 11

THE CLINICAL UTILITY OF THE MATTIS DEMENTIA RATING SCALE IN ASSESSING COGNITIVE DECLINE IN ALZHEIMER'S DISEASE

Miller, J. M., & Pliskin, N. H. (2006) · International Journal of Neuroscience · doi:10.1080/00207450600592164 · Cited by 11

The Early Detection of Brain Pathology in Alzheimer’s Disease

de Leon, M. J., Smith, G. S., Convit, A. J., GEORGE, A. E., Golomb, J. B., Flicker, C., McRae, T., Kluger, A., Tsui, W., Rusinek, H., et al. (1992) · Research and perspectives in Alzheimer's disease · doi:10.1007/978-3-642-46759-2_11 · Cited by 11

Elevated serum sodium is linked to increased amyloid‐dependent tau pathology, neurodegeneration, and cognitive impairment in Alzheimer's disease

Chen, Y., Wang, Z., Liu, X., Mao, Z., & Initiative, A. D. N. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16257 · Cited by 10

The Role of Clinical Assessment in the Era of Biomarkers

Carlos, A. F., & Josephs, K. A. (2023) · Neurotherapeutics · doi:10.1007/s13311-023-01410-3 · Cited by 11

The Effect of Clinical Characteristics and Subtypes on Amyloid Positivity in Patients with Amnestic Mild Cognitive Impairment

Kim, J. Y., Lim, J. H., Jeong, Y. J., Kang, D., & Park, K. W. (2019) · Dementia and Neurocognitive Disorders · doi:10.12779/dnd.2019.18.4.130 · Cited by 10

New Multi-task Learning Model to Predict Alzheimer’s Disease Cognitive Assessment

Huo, Z., Shen, D. G., & Huang, H. (2016) · Lecture notes in computer science · doi:10.1007/978-3-319-46720-7_37 · Cited by 9

Multiscale models of pharmacological, immunological and neurostimulation treatments in Alzheimer's disease

Vassilis Cutsuridis, A., & Moustafa, A. A. (2016) · Drug Discovery Today Disease Models · doi:10.1016/j.ddmod.2016.12.001 · Cited by 9

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Zhang, J., Wu, J., Li, Q., Caselli, R. J., Thompson, P. M., Ye, J., & Wang, Y. (2021) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2021.3070780 · Cited by 9

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Keyserling, H. F., & Mukundan, S. (2005) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2005.09.012 · Cited by 9

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Grunze, H., Schlösser, S., & Walden, J. (2000) · The World Journal of Biological Psychiatry · doi:10.3109/15622970009150580 · Cited by 9

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Coen, R. F., Swanwick, G., Maguire, C., Kirby, M., LAWLOR, B. A., Walsh, J. B., & Coakley, D. (1996) · Irish Journal of Psychological Medicine · doi:10.1017/s0790966700002421 · Cited by 9

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Restrepo, F. J. L., Lopera, N. E. T., Burgos, O. M. A., Vargas, S. A., Gutiérrez, J. E., Rosselli, M., & Ardila, A. (1999) · Revista de Neurología · doi:10.33588/rn.2901.99136 · Cited by 8

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Kobayashi, K., Shimoda, K., Higashima, M., Nakano, H., Mlyazu, K., Hayashi, M., Labata, O., & Koshino, Y. (2000) · The World Journal of Biological Psychiatry · doi:10.3109/15622970009150586 · Cited by 7

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Thiagarajan, S., Shaik, M. A., Venketasubramanian, N., Ting, E. Y., Hilal, S., & Chen, C. (2017) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000227 · Cited by 7

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Pfeffer, A. Z., Łuczywek, E., Gołębiowski, M., Czyźewski, K., & Barcikowska, M. (1999) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000017122 · Cited by 7

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Hénon, H. (2002) · Clinical and Experimental Hypertension · doi:10.1081/ceh-120015344 · Cited by 7

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Barnes, J., Foster, J., & Fox, N. C. (2007) · Biomarkers in Medicine · doi:10.2217/17520363.1.1.79 · Cited by 6

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Collerton, D., & FAIRBAIRN, A. F. (1985) · The Lancet · doi:10.1016/s0140-6736(85)91055-4 · Cited by 2

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Horn, R., Staab, B., Ostertun, B., Solymosi, L., & Möller, H. ‐. (1992) · Clinical Neuropharmacology · doi:10.1097/00002826-199202001-00193 · Cited by 3

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de Leon, M. J., McRae, T., Tsai, J., GEORGE, A. E., MARCUS, D., Freedman, M. S., Wolf, A., & McEwen, B. S. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92855-3 · Cited by 198

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George, A. E. (1992) · Neurobiology of Aging · doi:10.1016/0197-4580(92)90173-u · Cited by 1

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