Cited by 453Reproductive Health and TechnologiesAssisted Reproductive Technology and Twin PregnancyReproductive Biology and Fertility

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Intrauterine insemination or in-vitro fertilisation in idiopathic subfertility and male subfertility: a randomised trial and cost-effectiveness analysis

Goverde, Angelique J, McDonnell, Joseph, Vermeiden, Jan PW, Schats, Roel, Rutten, Frans FH, Schoemaker, Joop·2000·The Lancet

DOI 10.1016/s0140-6736(99)04002-7

Open this paper in CoChat — free account

Abstract

Background Couples affected by idiopathic subfertility or male subfertility have an estimated spontaneous conception rate of about 2% per cycle. Although various infertility treatments are available, counselling of a couple in their choice of treatment is difficult because of the lack of consistent data from good-quality comparative studies. We compared the results of treatment with intrauterine insemination (IUI) with those of in-vitro fertilisation (IVF), and did a cost-effectiveness analysis. Methods In a prospective, randomised, parallel trial, 258 couples with idiopathic subfertility or male subfertility were treated for a maximum of six cycles of either IUI in the spontaneous cycle (IUI alone), IUI after mild ovarian hyperstimulation, or IVF. The primary endpoint was a pregnancy resulting in at least one livebirth after treatment. Cost-effectiveness based on real costs was studied by Markov chain analysis. Findings 86 couples were assigned IUI alone, 85 IUI plus ovarian hyperstimulation, and 87 IVF. Ten couples dropped out before treatment began. Although the pregnancy rate per cycle was higher in the IVF group than in the IUI groups (12.2% vs 7.4% and 8.7%, respectively; p=0.09), the cumulative pregnancy rate for IVF was not significantly better than that for IUI. Couples in the IVF group were more likely than those in the IUI groups to give up treatment before their maximum of six attempts (37 [42%] drop-outs vs 13 [15%] and 14 [16%], respectively; p Interpretation Co…

Integrity signals

Registry

Crossref · 10.1016/s0140-6736(99)04002-7

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick, D. S., Carson, S. A., Coutifaris, C., Overstreet, J. W., Factor-Litvak, P. R., Steinkampf, M. P., Hill, J. A., Mastroianni, L., Buster, J. E., Nakajima, S. T., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901213400302 · Cited by 521
Delaying childbearing: effect of age on fecundity and outcome of pregnancy.
van Noord‐Zaadstra, B. M., Looman, C. W. N., Alsbach, H., Habbema, J. D. F., Velde, E. R. T., & Karbaat, J. (1991) · BMJ · doi:10.1136/bmj.302.6789.1361 · Cited by 446
The Economic Impact of Multiple-Gestation Pregnancies and the Contribution of Assisted-Reproduction Techniques to Their Incidence
Callahan, T. L., Hall, J. E., Ettner, S. L., Christiansen, C. L., Greene, M. F., & Crowley, W. F. (1994) · New England Journal of Medicine · doi:10.1056/nejm199407283310407 · Cited by 425
The prognosis for live birth among untreated infertile couples
Collins, J. A., Burrows, E., & Willan, A. R. (1995) · Fertility and Sterility · doi:10.1016/s0015-0282(16)57650-x · Cited by 361
The effectiveness of ovulation induction and intrauterine insemination in the treatment of persistent infertility: a meta-analysis
Hughes, E. G. (1997) · Human Reproduction · doi:10.1093/humrep/12.9.1865 · Cited by 275
IMPROVED CONCEPTION RATE AFTER INTRAUTERINE INSEMINATION OF WASHED SPERMATOZOA FROM MEN WITH POOR QUALITY SEMEN
Kerin, J. F., Peek, J., Warnes, G. M., Kirby, C. A., Jeffrey, R., Matthews, C. D., & Cox, L. W. (1984) · The Lancet · doi:10.1016/s0140-6736(84)90932-2 · Cited by 167
The probability of pregnancy after embryo transfer is affected by the age of the patient, cause of infertility, number of embryos transferred and the average morphology score, as revealed by multiple logistic regression analysis
Roseboom, T. J., Vermeiden, J. P. W., Schoute, E., Lens, J. W., & Schats, R. (1995) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a135842 · Cited by 144
Self-citation
Markov Models for Covariate Dependence of Binary Sequences
Muenz, L. R., & Rubinstein, L. (1985) · Biometrics · doi:10.2307/2530646 · Cited by 134
The ESHRE multicentre trial on the treatment of unexplained infertility: a preliminary report*
Crosignani, P. G., Walters, D. E., & Soliani, A. (1991) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137468 · Cited by 132
Patient dropout in an assisted reproductive technology program: implications for pregnancy rates
Land, J. A., Courtar, D. A., & Evers, J. L. H. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81515-4 · Cited by 130

Show all 26 references

Sorted by citations

Items 201–300 of 453

Should IVF be used as first-line treatment or as a last resort? A debate presented at the 2013 Canadian Fertility and Andrology Society meeting
Huang, L. N., Tan, J., Hitkari, J. A., & Dahan, M. H. (2014) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2014.10.004 · Cited by 18
The effect of ovarian stimulation on the outcome of intrauterine insemination
Gomez, R., Schorsch, M., Steetskamp, J., Hahn, T., Heidner, K., Seufert, R., & Skala, C. (2013) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-013-2952-3 · Cited by 16
A randomized controlled trial comparing the effectiveness of single versus double intrauterine insemination in unexplained infertility
Rahman, S. M., Malhotra, N., Kumar, S., Roy, K. K., & Agarwal, A. K. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.06.082 · Cited by 16
NEWS AROUND THE WORLD: Reflections on the Cost-Effectiveness of Recombinant FSH in Assisted Reproduction. The Clinician's Perspective
Balasch, J., & Barri, P. N. (2001) · Journal of Assisted Reproduction and Genetics · doi:10.1023/a:1026501821849 · Cited by 16
Intrauterine insemination + controlled ovarian hyperstimulation versus in vitro fertilisation in unexplained infertility: a systematic review and meta-analysis
Nandi, A., Gangopadhyay, R., White, D. M., & Tarek, E.-T. (2021) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-021-06277-3 · Cited by 15
A Comparison of the Cost-Effectiveness of In Vitro Fertilization Strategies and Stimulated Intrauterine Insemination in a Canadian Health Economic Model
Bhatti, T., & Baibergenova, A. (2008) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)32826-2 · Cited by 15
Contemporary Management of Unexplained Infertility
STEWART, J. D., Pasternak, M. C., Pereira, N., & Rosenwaks, Z. (2019) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000450 · Cited by 15
[Prognostic factors of pregnancy in intrauterine insemination].
Delgadillo, J. C. B., Ruiz, J. C. R., Munguía, A. C. M., Acosta, S. V., Solís, V. S., Villa, G. B., & Gaviño, F. G. (2006) · PubMed · Cited by 15
GnRH antagonist ganirelix prevents premature luteinization in IUI cycles: rationale for its use
Martinez-Salazar, J., Cerrillo, M., Quea, G., Pacheco, A., & García-Velasco, J. A. (2009) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60066-1 · Cited by 15
Pregnancy predictors in unexplained infertility after intrauterine insemination
Guan, H., Tang, H., Pan, L., Song, H. S., & Tang, L. (2021) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2021.102071 · Cited by 14
Prognostic profiles and the effectiveness of assisted conception: secondary analyses of individual patient data
van den Boogaard, N. M., Bensdorp, A. J., Rengerink, K. O., Barnhart, K. T., Bhattacharya, S., Custers, I. M., Coutifaris, C., Goverde, A. J., Guzick, D. S., Hughes, E., et al. (2013) · Human Reproduction Update · doi:10.1093/humupd/dmt035 · Cited by 14
Self-citation
Valuing infertility treatment: Why QALYs are inadequate, and an alternative approach to cost-effectiveness thresholds
Keller, E., & Chambers, G. M. (2022) · Frontiers in Medical Technology · doi:10.3389/fmedt.2022.1053719 · Cited by 16
Reduction of steps in the preparation of motile sperm for intrauterine insemination does not reduce efficacy of the procedure: simplified one-step swim-up method versus classic swim-up
Inaudi, P. (2002) · Human Reproduction · doi:10.1093/humrep/17.5.1288 · Cited by 14
Expectant management may reduce overtreatment in women affected by unexplained infertility confirmed by diagnostic laparoscopy
Cicco, S. D., Tagliaferri, V., Selvaggi, L. E., Romualdi, D., Florio, C. D., Immediata, V., Lanzone, A., & Guido, M. (2016) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-016-4246-z · Cited by 14
The place of the crossover design in infertility trials: a maximum likelihood approach
McDonnell, J., Goverde, A. J., & Vermeiden, J. P. W. (2004) · Human Reproduction · doi:10.1093/humrep/deh475 · Cited by 14
Self-citation
The Use of Novel Semen Quality Scores to Predict Pregnancy in Couples With Male‐Factor Infertility Undergoing Intrauterine Insemination
Bedaiwy, M. A., Sharma, R. K., Al-Hussaini, T. K., Mohamed, M. S., Aleem, A. M. A., Nelson, D. R., Thomas, A. J., Jr., & Agarwal, A. K. (2003) · Journal of Andrology · doi:10.1002/j.1939-4640.2003.tb02682.x · Cited by 14
Unexplained Infertility
Randolph, J. F. (2000) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-200012000-00019 · Cited by 14
Unexplained subfertility: diagnosis and management
Nandi, A., & Homburg, R. (2016) · The Obstetrician & Gynaecologist · doi:10.1111/tog.12253 · Cited by 13
The cost effectiveness of intracyctoplasmic sperm injection (ICSI)
Hollingsworth, B. P., Harris, A., & Mortimer, D. (2007) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-007-9175-0 · Cited by 13
Unexplained infertility: live-birth's prognostic factors to determine the ART management
Ohannessian, A., Loundou, A., Gnisci, A., Paulmyer‐Lacroix, O., Perrin, J., & Courbière, B. (2017) · Minerva Obstetrics and Gynecology · doi:10.23736/s0026-4784.17.04085-0 · Cited by 13
Total fertilization failure and idiopathic subfertility
Tanahatoe, S., McDonnell, J., Goverde, A. J., Hompes, P. G. A., & Lambalk, C. B. (2009) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-7-3 · Cited by 13
Self-citation
Ovarian stimulation protocols (anti-oestrogens, gonadotrophins with and without GnRH agonists/antagonists) for intrauterine insemination (IUI) in women with subfertility
Cantineau, A. E., Cohlen, B., & Heineman, M. J. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005356 · Cited by 13
Time intervals between semen production, initiation of analysis, and IUI significantly influence clinical pregnancies and live births
Punjabi, U. R., Mulders, H. V., de Velde, L. V., Goovaerts, I., Peeters, K., Cassauwers, W., Lyubetska, T., Clasen, K., Janssens, P., Zemtsova, O., et al. (2021) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-020-02020-0 · Cited by 12
The Livebirth Rate Per In Vitro Fertilization Cycle Is Higher Than The Cumulative Live Birth Rates of Intrauterine Insemination for Patients of Poseidon Group 3 With Unexplained Infertility
Wu, Y., Liu, H., & Liu, J. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.768975 · Cited by 13
In vitro fertilization (IVF) versus gonadotropins followed by IVF as treatment for primary infertility: a cost-based decision analysis
Kalra, S. K., Milad, M. P., & Grobman, W. A. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.03.049 · Cited by 12
Offering excess oocyte aspiration and vitrification to patients undergoing stimulated artificial insemination cycles can reduce the multiple pregnancy risk and accumulate oocytes for later use
Stoop, D., Landuyt, L. V., Paquay, R., Fatemi, H. M., Blockeel, C., Vos, M. D., Camus, M., den Abbeel, E. V., & Devroey, P. (2010) · Human Reproduction · doi:10.1093/humrep/deq026 · Cited by 12
A New Dawn for Intrauterine Insemination: Efficient and Prudent Practice will Benefit Patients, the Fertility Industry and the Healthcare Bodies
Bahadur, G. A., Homburg, R., & Al‐Habib, A. (2016) · The Journal of Obstetrics and Gynecology of India · doi:10.1007/s13224-016-0928-5 · Cited by 12
In vitro fertilisation for unexplained subfertility
Pandian, Z., Bhattacharya, S., Nikolaou, D., Vale, L. D., & Templeton, A. (2002) · doi:10.1002/14651858.cd003357 · Cited by 12
Live birth is not the only relevant outcome in research assessing assisted reproductive technology
Wang, Z., Cantineau, A. E., Hoek, A., van EEKELEN, R., Mol, B. W., & Wang, R. (2022) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2022.102306 · Cited by 11
Optimal lead follicle size in letrozole human menopausal gonadotrophin intrauterine insemination cycles with and without spontaneous LH surge
Chen, L., Jiang, S., Xi, Q., Li, W., Lyu, Q., & Kuang, Y. (2022) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.11.003 · Cited by 11
Evaluation of endometrial scratching on intrauterine insemination outcome and endometrial receptivity
Gupta, V., Radhakrishnan, G., Arora, V. K., & Singh, A. (2018) · Middle East Fertility Society Journal · doi:10.1016/j.mefs.2018.05.002 · Cited by 11
Is intrauterine insemination a viable treatment option for women over 43 years old? An analysis by ovarian stimulation protocol and sperm source
Ruiter‐Ligeti, J., Dahan, M. H., Steiner, N., Volodarsky‐Perel, A., & Buckett, W. M. (2020) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-020-01976-3 · Cited by 11
The case for initial treatment with intrauterine insemination as opposed toin vitrofertilization for idiopathic infertility
Homburg, R. (2003) · Human Fertility · doi:10.1080/1464770312331369373 · Cited by 11
Intrauterine insemination versus Fallopian tube sperm perfusion in non-tubal subfertility: a systematic review based on a Cochrane review*
Cantineau, A. E., Heineman, M. J., Al-Inany, H. G., & Cohlen, B. J. (2004) · Human Reproduction · doi:10.1093/humrep/deh523 · Cited by 11
Indications for IVF treatment: from diagnosis to prognosis
Macklon, N. S., & Fauser, B. C. J. M. (2004) · ePrints Soton (University of Southampton) · doi:10.3109/9780203012840-45 · Cited by 11
One triplet pregnancy in 510 controlled ovarian hyperstimulation and intrauterine insemination cycles
Healy, D., Rombauts, L. J. F., Vollenhoven, B. J., Kovacs, G. T., & Burmeister, L. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00259-0 · Cited by 11
IVF versus IUI with ovarian stimulation for unexplained infertility: a collaborative individual participant data meta-analysis
Lai, S., Wang, R., van Wely, M., Costello, M., Farquhar, C. M., Bensdorp, A. J., Custers, I. M., Goverde, A. J., Elzeiny, H., Mol, B. W., et al. (2023) · Human Reproduction Update · doi:10.1093/humupd/dmad033 · Cited by 10
Self-citation
Intrauterine Insemination With Double Ejaculate Compared With Single Ejaculate in Male Factor Infertility: A Pilot Study
Küçük, T., Sözen, E., & Buluç, B. (2008) · Journal of Andrology · doi:10.2164/jandrol.107.004754 · Cited by 10
Economics of treatments for male infertility
Shin, D., & Honig, S. C. (2002) · Urologic Clinics of North America · doi:10.1016/s0094-0143(02)00078-2 · Cited by 10
Controlled ovarian stimulation should not be preferred for male infertility treated with intrauterine insemination: a retrospective study
Tang, Y., He, Q.-D., Zhang, T., Wang, J., Huang, S.-C., & Ye, Y. (2021) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-021-00730-3 · Cited by 9
Assisted reproduction counseling in women aged 40 and above: a cohort study
Brucker, M. D., Tournaye, H. J., Haentjens, P., Verheyen, G., Collins, J. A., & Camus, M. (2013) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-013-0085-z · Cited by 9
In vitro fertilisation for unexplained subfertility
Sunkara, S. K., Kamath, M. S., Pandian, Z., Gibreel, A., & Bhattacharya, S. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003357.pub5 · Cited by 9
Cost-effective, evidence-based infertility care
Daya, S. (2000) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-200006000-00010 · Cited by 9
Analysis of factors associated with IUI pregnancy outcomes in elderly and young patients
Yu, C., Bai, L., mei-Zhou, J., yu-Wang, X., Chen, L., & Zhang, J. (2024) · BMC Women s Health · doi:10.1186/s12905-024-02934-2 · Cited by 8
Replacing IUI with IVF for initial treatment of unexplained infertility: why this NICE recommendation is cause for concern
Woodward, B. J., Tomlinson, M. J., & Kirkman‐Brown, J. (2016) · Human Fertility · doi:10.1080/14647273.2016.1182220 · Cited by 8
Impact of gonadotropin-releasing hormone antagonist addition on pregnancy rates in gonadotropin-stimulated intrauterine insemination cycles
Jain, S., & Majumdar, A. (2016) · Journal of Human Reproductive Sciences · doi:10.4103/0974-1208.192053 · Cited by 8
Clomiphene Citrate versus Letrozole for Ovarian Stimulation in Therapeutic Donor Sperm Insemination
Hachem, H. E., Antaki, R., Sylvestre, C. V., Kadoch, I.-J., Lapensée, L., & Bouet, P. (2016) · Gynecologic and Obstetric Investigation · doi:10.1159/000452665 · Cited by 8
Clinical success of IUI cycles with donor sperm is not affected by total inseminated volume: a RCT
Rodriguez-Purata, J., Latre, L., Ballester, M., González-Llagostera, C., Rodríguez, I., González-Foruria, I., Buxaderas, R., Martínez, F., Barri, P. N., & Coroleu, B. (2018) · Human Reproduction Open · doi:10.1093/hropen/hoy002 · Cited by 8
Effects of clomiphene citrate for prevention of premature luteinizing hormone surge in those undergoing intrauterine insemination outcome: A randomized, double-blind, placebo-controlled trial
Alborzi, M., Zarei, A., Alborzi, S., Askary, E., & Shahbazi, F. (2018) · Journal of Advanced Pharmaceutical Technology amp Research · doi:10.4103/japtr.japtr_293_18 · Cited by 8
Should intrauterine inseminations still be proposed in cases of unexplained infertility? Retrospective study and literature review
Merviel, P., Labarre, M., James, P., Bouée, S., Chabaud, J., Roche, S., Cabry, R., Scheffler, F., Lourdel, E., Benkhalifa, M., et al. (2022) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-021-06351-w · Cited by 8
Coste de las técnicas de reproducción asistida en un hospital público
Espigares, J. L. N., Navarro, L. M., Alcalá, J. A. C., & Torres, E. H. (2006) · Gaceta Sanitaria · doi:10.1157/13093207 · Cited by 8
Multivariate Markov chain analysis of the probability of pregnancy in infertile couples undergoing assisted reproduction
McDonnell, J. (2002) · Human Reproduction · doi:10.1093/humrep/17.1.103 · Cited by 8
Self-citation
Does intrauterine insemination timing matter for achieving pregnancy during ovulation induction using gonadotropins? A retrospective cohort study
Yumuşak, Ö. H., Kahyaoğlu, S., Pekcan, M. K., İşçi, E., Çınar, M., & Taşçı, Y. (2016) · Journal of the Chinese Medical Association · doi:10.1016/j.jcma.2016.06.005 · Cited by 8
Comparison between semen parameters in specimens collected early in the morning and in the evening
Shimomura, Y., Shin, T., Osaka, A., Inoue, Y., Iwahata, T., Kobori, Y., Ide, H., Soh, S., & Okada, H. (2020) · Systems Biology in Reproductive Medicine · doi:10.1080/19396368.2020.1727994 · Cited by 8
How effective is assisted reproduction technology? A model assessment
Léridon, H. (2005) · Revue d Épidémiologie et de Santé Publique · doi:10.1016/s0398-7620(05)84774-1 · Cited by 8
An intrauterine insemination audit at tertiary care hospital: A 4½ years' retrospective analysis of 800 intrauterine insemination cycles
Fauzdar, A., Wadhwa, L., & Wadhwa, S. N. (2018) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_34_18 · Cited by 8
Superovulation and Intrauterine Insemination in Cases of Treated Mild Pelvic Disease
Singh, M., Goldberg, J. M., Falcone, T., Nelson, D. R., Pasqualotto, E. B., Attaran, M., & Agarwal, A. (2001) · Journal of Assisted Reproduction and Genetics · doi:10.1023/a:1026446612485 · Cited by 8
Stimulated intrauterine insemination (SIUI) and donor insemination (DI) as first line management for a selected subfertile population: the Manchester experience
Vitthala, S., Gelbaya, T. A., Hunter, H. R., Roberts, S. A., & Nardo, L. G. (2008) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-008-9251-0 · Cited by 8
The clomiphene citrate challenge test (CCCT) in women with elevated basal FSH: Biological significance and predictive value
Ragni, G., Chiaffarino, F., Scarduelli, C., Bonetti, S., Nicolosi, A. E., Arnoldi, M., & Somigliana, E. (2008) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2008.06.009 · Cited by 8
Intrauterine Insemination
Allahbadia, G. N., & Merchant, R. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8376-2_11 · Cited by 8
Access to assisted reproduction services and infertility treatment in Belgium in the context of the European countries
Ombelet, W. U. A. M. (2007) · Pharmaceuticals Policy and Law · doi:10.3233/ppl-2007-00161 · Cited by 7
Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples
Rakic, L., Kostova, E., Cohlen, B., & Cantineau, A. E. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003854.pub2 · Cited by 7
Intrauterine Insemination and Male Subfertility
Levine, B. A., & GRIFO, J. A. (2008) · Urologic Clinics of North America · doi:10.1016/j.ucl.2008.01.002 · Cited by 7
The effect of nasal oxytocin on pregnancy rates following intrauterine insemination: double-blind, randomized, clinical pilot study
Ochsenkühn, R., Pavlik, R., Hecht, S., von Schönfeldt, V., Rogenhofer, N. N., & Thaler, C. (2009) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-009-1284-9 · Cited by 7
Male infertility: Tales of progress and frustration
Ford, W. C. L. (2002) · Human Fertility · doi:10.1080/1464727022000199931 · Cited by 7
Intrauterine Insemination (IUI)
Beyer, D. A. (2009) · Gynäkologische Endokrinologie · doi:10.1007/s10304-009-0320-y · Cited by 7
Effects of letrozole combined with human menopausal gonadotropin in ovarian stimulation for intrauterine insemination cycles
Yu, X., Cao, Z., Hou, W., Hu, W., & Yan, G. (2019) · Annals of Translational Medicine · doi:10.21037/atm.2019.11.58 · Cited by 7
Role of In Vitro Fertilization (IVF) in Unexplained Infertility Management: A Systematic Review
Mahabbat, N. A. A., Khan, T. A., Elyas, M. F., Mahabbat, A. A., & Oraif, A. (2024) · Cureus · doi:10.7759/cureus.72527 · Cited by 6
Natural procreative technology for infertility and recurrent miscarriage
Tham, E. H., Schliep, K. C., & Stanford, J. B. (2012) · Canadian Family Physician · Cited by 6
Severity of oligo-asteno-teratozoospermia no longer determines overall success rate in male subfertility
Brandes, M., Hamilton, C. J. C. M., van der Steen, J. O. M., de Bruin, J. P., Bots, R. S. G. M., Nelen, W. L. D. M., & Kremer, J. A. M. (2011) · International Journal of Andrology · doi:10.1111/j.1365-2605.2010.01128.x · Cited by 6
Which is the best intrauterine insemination timing choice following exogenous hCG administration during ovulation induction by using clomiphene citrate treatment? A retrospective study
Yumuşak, Ö. H., Kahyaoğlu, S., Pekcan, M. K., İşçi, E., Ozyer, S. S., Çiçek, M. N., Taşçı, Y., & Erkaya, S. (2016) · SpringerPlus · doi:10.1186/s40064-016-2992-9 · Cited by 6
Open-label, Prospective, Investigator Initiated Study to Assess the Clinical Role of Oral Natural or Synthetic Progesterone During Stimulated IUI Cycles for Unexplained Infertility
Malhotra, J. (2016) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2016/17058.7106 · Cited by 6
An overview of intrauterine insemination and ovulation induction
Brinsden, P. R., & Dickey, R. P. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511642159.002 · Cited by 6
Effective use of assisted reproduction
Bhattacharya, S. (2003) · Human Fertility · doi:10.1080/1464770312331369283 · Cited by 6
Economic evaluation of the administration of follitropin-β with a pen device
Bruynesteyn, K., Bonse, G., Braat, D., Fauser, B. C. J. M., Devroey, P., & van Genugten, M. (2005) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)61295-3 · Cited by 6
Single versus double intrauterine insemination: are outcomes affected?
Zeyneloğlu, H. B. (2004) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-200406000-00008 · Cited by 6
Fertility and Obesity
Kesmodel, U. S. (2012) · Springer eBooks · doi:10.1007/978-3-642-25023-1_2 · Cited by 5
Place des techniques d’assistance médicale à la procréation
Amar-Hoffet, A., Hedon, B., & Belaisch-Allart, J. (2010) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/s0368-2315(10)70034-x · Cited by 5
Modification of Assisted Reproduction Techniques to Prevent Preterm Birth
Pandian, Z., Templeton, A. A., & Bhattacharya, S. (2004) · Clinical Obstetrics & Gynecology · doi:10.1097/01.grf.0000141449.23192.21 · Cited by 5
Predictive Factors For Intrauterine Insemination Success: Analysis Of Semen Parameters Affecting Outcome
Jellad, S., Basly, M., Chibani, M., & Rachdi, R. (2014) · The Internet Journal of Urology · Cited by 5
Comparative study of intracytoplasmic sperm injection and in vitro fertilization with high insemination concentration in sibling oocytes in the treatment of unexplained infertility.
Chiamchanya, C., Tor-udom, P., & Gamnarai, N. (2008) · PubMed · Cited by 5
Inseminationsbehandlung
Dorn, C. H. V. (2013) · Springer eBooks · doi:10.1007/978-3-642-30181-0_16 · Cited by 5
Ovarian stimulation length, number of follicles higher than 17 mm and estradiol on the day of human chorionic gonadotropin administration are risk factors for multiple pregnancy in intrauterine insemination
Garrido, N., de Melo, M. A. B., Simón, C., Remohi, J. A., Pellicer, A., & Meseguer, M. (2007) · Reproductive Medicine and Biology · doi:10.1111/j.1447-0578.2007.00160.x · Cited by 5
Wildfire smoke exposure is associated with decreased sperm concentration and total motile sperm count
Lindell, L. X., Holt, S. K., Petersen, E., Gunaje, N., Amighi, A., Haack, A. J., Bui, A. H., Nasseri, R., Crisostomo-Wynne, T. C., Karr, C. J., et al. (2025) · Fertility and Sterility · doi:10.1016/j.fertnstert.2025.08.031 · Cited by 5
Unexplained subfertility: a pragmatic approach
Toukhy, T. E. (2002) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443610220130481 · Cited by 4
Intrauterine insemination, what do we really know? A critical appraisal of the literature.
Steures, P., van der Steeg, J. W., Hompes, P. G. A., Bossuyt, P. M., Mol, B. W., & van der Veen, F. (2008) · Pure Amsterdam UMC · Cited by 4
Female Infertility
Broekmans, F. J., & Fauser, B. C. J. M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00132-3 · Cited by 4
Can the use of diagnostic and prognostic categorisation tailor the need for assisted reproductive technology in infertile couples?
Song, Z., Li, W., O’Leary, S., Roberts, B., Alvino, H., Tremellen, K. P., Gadalla, M. A., Wang, R., & Mol, B. W. (2020) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.13273 · Cited by 4
Medical Approaches to Ovarian Stimulation for Infertility
Fauser, B. C. J. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-47912-7.00030-5 · Cited by 6
Stimulated Intrauterine Insemination: Efficient, cost-effective, safe?
Lenton, E. A. (2004) · Human Fertility · doi:10.1080/14647270400016332 · Cited by 4
Intrauterine insemination in Jamaica as a low‐cost subfertility treatment in a low‐resource region
Christie, L. R., Harriott, J. A., DaCosta, V., Wynter, S. H., Everett, D., & Foster, R. (2011) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2010.10.017 · Cited by 4
Solutions thérapeutiques pour les infertilités masculines
Hamamah, S., Anahory, T., Ferrière, A., Loup, V., Reyftmann, L., & Déchaud, H. (2009) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/s0368-2315(09)70233-9 · Cited by 4
Medical Approaches to Ovarian Stimulation for Infertility
Fauser, B. C. J. M. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-2758-2.00030-5 · Cited by 4
Retracted: Cervical mucus removal prior to intrauterine insemination: a randomized trial
Maher, M. A., Sayyed, T., & Elkhouly, N. I. (2017) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.15003 · Cited by 6
Retracted
Pregnancy outcome after IUI for male and idiopathic infertility using a new simplified method for sperm preparation
Siam, E. M. (2011) · Middle East Fertility Society Journal · doi:10.1016/j.mefs.2011.07.004 · Cited by 3
Dose-finding study of Leuplin depot for prevention of premature luteinizing hormone surge during controlled ovarian stimulation: a pilot study in intrauterine insemination treatment
Chen, H.-J., Lin, Y., Huang, M., Seow, K., Huang, L., Hsieh, B., Tzeng, C., & Hwang, J. (2016) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2014.12.012 · Cited by 3
Systematischer Ansatz zur Diagnostik und Therapie bei Kinderwunschpaaren
Nawroth, F., Ludwig, M. Z., & Keck, C. (2015) · Springer eBooks · doi:10.1007/978-3-662-46014-6_4 · Cited by 3
Effective empiric treatment of infertility
Nelson, H., & Adamson, G. D. (2006) · Sexuality, reproduction & menopause · doi:10.1016/j.sram.2006.08.008 · Cited by 3
Intrauterine insemination: facts and fairy-tales
Cohlen, B. J. (2005) · International Congress Series · doi:10.1016/j.ics.2004.12.032 · Cited by 3
Intrauterine Insemination - eine übersicht
Schröder, A. K., Banz, C., Diedrich, K., & Ludwig, M. Z. (2002) · Reproduktionsmedizin · doi:10.1007/s00444-002-0374-y · Cited by 3

Authors: Goverde, A. J., McDonnell, J., Vermeiden, J. P., Schats, R., Rutten, F. F., & Schoemaker, J.
Affiliations: Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Erasmus University Rotterdam (NL)
Corresponding author: Goverde, Angelique J
ORCID: Goverde, Angelique J
Venue: The Lancet
Publisher: Elsevier BV
Published: 2000-01
Volume: 355
Issue: 9197
Pages: 13-18
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(99)04002-7
OpenAlex: W2110055479
Cited by: 453
References: 26
Citations by year: 2026: 3 · 2025: 5 · 2024: 3 · 2023: 6 · 2022: 11 · 2021: 19 · 2020: 13 · 2019: 14 · 2018: 12 · 2017: 18 · 2016: 19 · 2015: 14 · 2014: 12 · 2013: 24 · 2012: 16
FWCI: 20.78
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
DigitalGeorgetown (Georgetown University Library) (submittedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Keywords: in vitro fertilization, male subfertility, cost-effectiveness, ovarian hyperstimulation, treatment discontinuation, Markov chain analysis
MeSH terms: Adult, Cost-Benefit Analysis, Female, Fertilization in Vitro, Humans, Infertility, Insemination, Artificial, Male, Markov Chains, Pregnancy, Sperm Count, Treatment Outcome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Intrauterine insemination or in-vitro fertilisation in idiopathic subfertility and male subfertility: a randomised trial and cost-effectiveness analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks