The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: a preliminary study
Abstract
This paper describes an extensive biocompatibility evaluation of biodegradable starch-based materials aimed at orthopaedic applications as temporary bone replacement/fixation implants. For that purpose, a polymer (starch/ethylene vinyl alcohol blend, SEVA-C) and a composite of SEVA-C reinforced with hydroxyapatite (HA) particles, were evaluated in both in vitro and in vivo assays. For the in vitro analysis cell culture methods were used. The in vivo tissue reactions were evaluated in an intramuscular and intracortical bone implantation model on goats, using light and scanning electron microscopy. A computerized image analysis system was used to obtain histomorphometric data regarding bone contact and remodelling after 6 and 12 weeks of implantation. In both in vitro and in vivo models, the SEVA-C-based materials did not induce adverse reactions, which in addition to their bone-matching mechanical properties makes them promising materials for bone replacement fixation.
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Athanasiou, K. A., Niederauer, G. G., & Agrawal, C. M. (1996) · Biomaterials · doi:10.1016/0142-9612(96)85754-1 · Cited by 1,497
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Water Soluble Polymers for Pharmaceutical Applications
Kadajji, V. G., & Betageri, G. V. (2011) · Polymers · doi:10.3390/polym3041972 · Cited by 606
PEG- and Peptide-Grafted Aliphatic Polyesters by Click Chemistry
Parrish, B., Breitenkamp, R. B., & Emrick, T. (2005) · Journal of the American Chemical Society · doi:10.1021/ja050310n · Cited by 579
Mano, J. F., Sousa, R. A., Boesel, L. F., Neves, N. M., & Reis, R. L. (2004) · Composites Science and Technology · doi:10.1016/j.compscitech.2003.09.001 · Cited by 450
Self-citationMano, J. F., Koniarova, D., & Reis, R. L. (2003) · Journal of Materials Science: Materials in Medicine · doi:10.1023/a:1022015712170 · Cited by 395
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Metadata
- Authors
- Mendes, S. C., Reis, R. L., Bovell, Y. P., Cunha, A. M., van Blitterswijk, C. A., & de Bruijn, J. D.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2001-01
- Volume
- 22
- Issue
- 14
- Pages
- 2057-2064
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2006827675
- Cited by
- 203
- References
- 1
- FWCI
- 12.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mendes, S. C., Reis, R. L., Bovell, Y. P., Cunha, A. M., van Blitterswijk, C. A., & de Bruijn, J. D. (2001). Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: a preliminary study. Biomaterials. https://doi.org/10.1016/s0142-9612(00)00395-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
