The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Foot-and-mouth disease virus
Open accessAbstract
Foot-and-mouth disease virus (FMDV) is an aphthovirus of the family Picornaviridae and the etiological agent of the economically most important animal disease. As a typical picornavirus, FMD virions are nonenveloped particles of icosahedral symmetry and its genome is a single stranded RNA of about 8500 nucleotides and of positive polarity. FMDV RNA is infectious and it replicates via a complementary, minus strand RNA. FMDV RNA replication is error-prone so that viral populations consist of mutant spectra (quasispecies) rather than a defined genomic sequence. Therefore FMDV in nature is genetically and antigenically diverse. This poses important challenges for the diagnosis, prevention and control of FMD. A deeper understanding of FMDV population complexity and evolution has suggested requirements for a new generation of anti-FMD vaccines. This is relevant to the current debate on the adequacy of non-vaccination versus vaccination policies for the control of FMD.
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Cites
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Self-citationStructure of the RNA-dependent RNA polymerase of poliovirus
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Structure of a major immunogenic site on foot-and-mouth disease virus
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Metadata
- Authors
- Domingo, E., Baranowski, E., Escarmı́s, C., & Sobrino, F.
- Venue
- Comparative Immunology, Microbiology and Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2002-10
- Volume
- 25
- Issue
- 5-6
- Pages
- 297-308
- ISSN
- 0147-9571 (ISSN-L)
- OpenAlex
- W1970595234
- Cited by
- 332
- References
- 35
- FWCI
- 17.93
- Type
- journal article
- Language
- en
- Open access
- green
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- Domingo, E., Baranowski, E., Escarmı́s, C., & Sobrino, F. (2002). Foot-and-mouth disease virus. Comparative Immunology, Microbiology and Infectious Diseases. https://doi.org/10.1016/s0147-9571(02)00027-9
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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