Cited by 161Mental Health Treatment and AccessTuberculosis Research and EpidemiologyAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Depression, anxiety comorbidity, and disability in tuberculosis and chronic obstructive pulmonary disease patients: applicability of GHQ-12

Orhan Aydin, Ismail, Uluşahin, Aylin·2001·General Hospital Psychiatry

Abstract

Our aim was to study anxiety and/or depression comorbidity and the influence of these comorbid conditions on disability for 3 clinical groups of pulmonary tuberculosis and chronic obstructive pulmonary disease (COPD). We also investigated the applicability of General Health Questionnaire 12 (GHQ12) for these clinical groups as a simple screening test for psychiatric comorbidity. A total of 157 male inpatients were included in the study: 42 with recently diagnosed (RDtb), 39 with defaulted (Dtb), 39 with multidrug resistant tuberculosis (MDRtb) and 38 with COPD. The presence of depression and anxiety was assessed by Composite International Diagnostic Interview (CIDI). Disability was evaluated by Brief Disability Questionnaire. The validity of GHQ12 for the study groups was examined in order to determine a functional cut-off point. Depression and/or anxiety comorbidity was 19% for RDtb, 21.6% for Dtb, 25.6% for MDRtb and 47.3% for COPD. Patients with psychiatric comorbidity had higher disability scores than the group without psychiatric comorbidity. For the tuberculosis group a 3/4 cut-off point of GHQ had 80.7% sensitivity and 87.1% specificity while a 5/6 cut-off point with 83.3% sensitivity and 80% specificity was applicable to the COPD group.

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Crossref · 10.1016/s0163-8343(01)00116-5

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Research works printed but not linked: 8

  1. Utkaner, 1997, Assessing anxiety and depression in tuberculosis patients, Tuberculosis and Thorax, 45, 199
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  6. Kaplan, 1995, Mental disorders, and disability in a primary health care clinic in semi-rural area, Turkish Journal of Psychiatry, 6, 169
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Metadata

Authors
Orhan Aydin, I., & Uluşahin, A.
Affiliations
Hacettepe University (TR)
Corresponding author
Uluşahin, Aylin
Venue
General Hospital Psychiatry
Publisher
Elsevier BV
Published
2001-03
Volume
23
Issue
2
Pages
77-83
ISSN
0163-8343 (ISSN-L)
OpenAlex
W2070878359
Cited by
161
References
33
Citations by year
2026: 3 · 2025: 3 · 2024: 6 · 2023: 3 · 2022: 3 · 2021: 7 · 2020: 10 · 2019: 7 · 2018: 7 · 2017: 11 · 2016: 5 · 2015: 8 · 2014: 9 · 2013: 7 · 2012: 10
FWCI
2.74
Type
journal article
Language
en
Open access
closed
Locations
  • General Hospital Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
Environmental Research and Education Foundation
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
depression, anxiety, psychiatric comorbidity, tuberculosis, chronic obstructive pulmonary disease, disability, GHQ-12, screening validity, multidrug-resistant tuberculosis, treatment default, Composite International Diagnostic Interview
MeSH terms
Adult, Aged, Anxiety, Cross-Sectional Studies, Depression, Humans, Lung Diseases, Obstructive, Male, Mass Screening, Middle Aged, Psychiatric Status Rating Scales, Sensitivity and Specificity, Tuberculosis, Pulmonary, Turkey, Comorbidity

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