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Endoscopic sinus surgery in cystic fibrosis: do patients benefit from surgery?
Abstract
Objective To examine the effects of endoscopic sinus surgery on the pulmonary status of cystic fibrosis (CF) patients through the objective parameters of steroid use, pulmonary function tests (PFTs), and inpatient hospital days (IHDs). Methods Retrospective chart review of all patients with CF who underwent endoscopic sinus surgery from 1993 to 1999 at a tertiary care children's hospital. Preoperative pulmonary function, inhaler and steroid use, and IHDs were compared to postoperative parameters within a 1-year period. Results Sixty-six patients, including eight lung transplant patients, underwent a total of 112 endoscopic sinus surgery procedures; 25 patients underwent more than one procedure. Patients were taking oral steroids preoperatively in 28% of procedures and inhaled steroids in 40%. Postoperatively, there was no statistically significant change in oral or inhaled steroid use, or in postoperative pulmonary function. If the index hospitalization, which was often for reasons not related to sinus disease, was considered part of the preoperative time period, endoscopic sinus surgery (ESS) was noted to result in a marked reduction (9.5 days (adjusted), P=0.001) in hospital days during the subsequent 6 months. If the date of the procedure alone was used to define pre- and postoperative time periods, the reduction in postoperative days was more modest and not statistically significant (3.5 days (adjusted), P=0.21). Conclusions Although we found no statistically significant…
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Surgery may be beneficial in patients with nasal polyps with associated asthma, aspirin-exacerbated respiratory disease, or cystic fibrosis.
“Surgery may be beneficial in patients with NP with associated asthma [228,229], AERD [230], or cystic fibrosis [231-233].”
From Position Paper on Nasal Obstruction: Evaluation and Treatment (2018) · cites this paper as [231]
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Research works printed but not linked: 40
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Cited by
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Position Paper on Nasal Obstruction: Evaluation and Treatment
SEAIC Rhinoconjunctivitis Committee & SEORL Rhinology, A., Valero, A., Navarro, A., del Cuvillo, A., Alobid, I., Benito, Jr., Colás, C., de los Santos, G., Fernández Liesa, R., García-Lliberós, A., et al. (2018) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0232 · Cited by 76
Metadata
- Authors
- Rosbe, K. W., Jones, D. T., Rahbar, R., Lahiri, T., & Auerbach, A. D.
- Affiliations
- Kaiser Permanente (US)
- Boston Children's Hospital (US)
- University of California, San Francisco (US)
- Corresponding author
- Rosbe, Kristina W
- Venue
- International Journal of Pediatric Otorhinolaryngology
- Publisher
- Elsevier BV
- Published
- 2001-11
- Volume
- 61
- Issue
- 2
- Pages
- 113-119
- ISSN
- 0165-5876 (ISSN-L)
- OpenAlex
- W1999517477
- Cited by
- 72
- References
- 0
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 7 · 2018: 2 · 2017: 4 · 2016: 2 · 2015: 6 · 2014: 5 · 2013: 8 · 2012: 8
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Pediatric Otorhinolaryngology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- endoscopic sinus surgery, cystic fibrosis, lung function, inhaled corticosteroids, oral corticosteroids, length of hospital stay, lung transplant recipients, pediatric patients, sinus surgery outcomes
- MeSH terms
- Adolescent, Adrenal Cortex Hormones, Child, Child, Preschool, Cystic Fibrosis, Endoscopy, Female, Follow-Up Studies, Humans, Male, Paranasal Sinus Diseases, Probability, Respiratory Function Tests, Retrospective Studies, Sensitivity and Specificity, Treatment Outcome
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