Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: acquisition and performance of the DRL-60s test
Abstract
CD. However, the pattern of responding at DRL-60s suggested poor schedule control for the WKY rats. Therefore, the performance of SHR in the DRL test does not appear to represent a valid model of ADHD. Further, our findings with the WKY rat suggest that this strain is a poor behavioural control for the SHR.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Impulsivity is seen in SHR as an inability to inhibit a response during the extinction phase of an operant task, and an inability to delay a response in order to obtain a larger reward.
“Impulsivity is seen in SHR as an inability to inhibit a response during the extinction phase of an operant task, and an inability to delay a response in order to obtain a larger reward [452,454].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [454]
The citation lists haven’t been fetched yet
References 28 · Cited by 63
- Authors
- Bull, E., Reavill, C., Hagan, J. J., Overend, P., & Jones, D. N. C.
- Affiliations
- GlaxoSmithKline (United Kingdom) (GB)
- Corresponding author
- Jones, Declan N.C
- Venue
- Behavioural Brain Research
- Publisher
- Elsevier BV
- Published
- 2000-04
- Volume
- 109
- Issue
- 1
- Pages
- 27-35
- ISSN
- 0166-4328 (ISSN-L)
- OpenAlex
- W2132838180
- Cited by
- 63
- References
- 28
- Citations by year
- 2025: 2 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 1 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 3 · 2014: 2 · 2013: 1 · 2012: 3
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioural Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- spontaneously hypertensive rats, attention deficit hyperactivity disorder, animal model validity, differential reinforcement of low rates, impulsivity, schedule control, sustained attention, Wistar-Kyoto rats, Sprague-Dawley rats, hyperactivity, response rate
- MeSH terms
- Animals, Attention, Attention Deficit Disorder with Hyperactivity, Brain, Disease Models, Animal, Genotype, Impulsive Behavior, Male, Motivation, Motor Activity, Rats, Inbred SHR, Rats, Inbred WKY, Mental Recall, Reinforcement Schedule, Species Specificity, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review