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Physiology and genetics of the dimorphic fungus Yarrowia lipolytica
Open accessAbstract
The ascomycetous yeast Yarrowia lipolytica (formerly Candida, Endomycopsis, or Saccharomyces lipolytica) is one of the more intensively studied 'non-conventional' yeast species. This yeast is quite different from the well-studied yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe with respect to its phylogenetic evolution, physiology, genetics, and molecular biology. However, Y. lipolytica is not only of interest for fundamental research, but also for biotechnological applications. It secretes several metabolites in large amounts (i.e. organic acids, extracellular proteins) and the tools are available for overproduction and secretion of foreign proteins. This review presents a comprehensive overview on the available data on physiology, cell biology, molecular biology and genetics of Y. lipolytica.
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Cited by
Tai, M., & Stephanopoulos, G. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2012.08.007 · Cited by 678
Madzak, C., Gaillardin, C., & Beckerich, J.-M. (2004) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2003.10.027 · Cited by 386
Self-citationPhilippini, R. R., Martiniano, S. E., Ingle, A. P., Franco Marcelino, P. R., Silva, G. M., Barbosa, F. G., dos Santos, J. C., & da Silva, S. S. (2020) · Frontiers in Energy Research · doi:10.3389/fenrg.2020.00152 · Cited by 112
Engineering the Oleaginous Yeast Yarrowia Lipolytica to Produce the Aroma Compound β-Ionone
Czajka, J. J., Nathenson, J. A., Benites, V. T., Baidoo, E. E. K., Cheng, Q., Wang, Y., & Tang, Y. J. (2018) · Microbial Cell Factories · doi:10.1186/s12934-018-0984-x · Cited by 109
Maguire, S. L., Wang, C., Holland, L. M., Brunel, F., Neuvéglise, C., Nicaud, J.-M., Zavrel, M., White, T. C., Wolfe, K. H., & Butler, G. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004076 · Cited by 69
Metadata
- Authors
- Barth, G., & Gaillardin, C. M.
- Venue
- FEMS Microbiology Reviews
- Publisher
- Oxford University Press
- Published
- 1997-04-01
- Volume
- 19
- Issue
- 4
- Pages
- 219-237
- ISSN
- 0168-6445 (ISSN-L)
- OpenAlex
- W1991349267
- Cited by
- 551
- References
- 0
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Physiology and genetics of the dimorphic fungus Yarrowia lipolytica. https://app.cochat.ai/papers/10.1016/s0168-6445(97)00002-8
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- Barth, G., & Gaillardin, C. M. (1997). Physiology and genetics of the dimorphic fungus Yarrowia lipolytica. FEMS Microbiology Reviews. https://doi.org/10.1016/s0168-6445(97)00002-8
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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