The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
EASL International Consensus Conference on Haemochromatosis
Open accessAbstract
The precise frequency of the different iron overload states due to haemochromatosis (HC) is unknown and need to be addressed in population studies ( 1. Bacon BR Powell LW Adams PC Kresina TF Hoofnagle JH Molecular medicine and haemochromatosis: at the crossroads. Gastroenterology. 1999; 116: 193-207 Abstract Full Text Full Text PDF PubMed Scopus (268) Google Scholar , 2. Pietrangelo A Haemochromatosis 1998: is one gene enough?. J Hepatol. 1998; 29: 502-509 Abstract Full Text PDF PubMed Scopus (30) Google Scholar ). The appropriate terminology for different iron overload states along the continuum is given below. The expert panel considers it both appropriate and feasible to define an over-accumulation state distinct from haemochromatosis. “Excess body iron storage” (iron overload) [haemosiderosis=iron staining in tissues] may be: i) Minimal: ∼1.5g (hepatic iron concentration, HIC, >30 μM/g) (?pathological significance: e.g. porphyria cutanea tarda (PCT); ii) Modest: 2–5 g (HIC>100 μM/g; serum ferritin approx 500 μg/l) (seen in chronic liver disease, haemolytic disorders, PCT, etc.); iii) Severe: >5 g (HIC >200 μM/g; serum ferritin approx 750 μg/l).
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Citations
Cites
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R., Ellis, M. C., Fullan, A., et al. (1996) · Nature Genetics · doi:10.1038/ng0896-399 · Cited by 3,664
Cited by
Hereditary Hemochromatosis — A New Look at an Old Disease
Pietrangelo, A. (2004) · New England Journal of Medicine · doi:10.1056/nejmra031573 · Cited by 992
Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA
Beutler, E., Felitti, V. J., Koziol, J. A., Ho, N. J., & Gelbart, T. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07447-0 · Cited by 823
HFE Gene and Hereditary Hemochromatosis: A HuGE Review
Hanson, E. H. (2001) · American Journal of Epidemiology · doi:10.1093/aje/154.3.193 · Cited by 432
Powell, L. W., Seckington, R. C., & Deugnier, Y. (2016) · The Lancet · doi:10.1016/s0140-6736(15)01315-x · Cited by 266
Self-citationPrevalence of Body Iron Excess in the Metabolic Syndrome
Bozzini, C., Girelli, D., Olivieri, O., Martinelli, N., Bassi, A., De Matteis, G., Tenuti, I., Lotto, V., Friso, S., Pizzolo, F., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.8.2061 · Cited by 224
Metadata
- Authors
- Adams, P., Brissot, P., & Powell, L. W.
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2000-09
- Volume
- 33
- Issue
- 3
- Pages
- 487-496
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W1995735496
- Cited by
- 284
- References
- 1
- FWCI
- 13.44
- Type
- journal article
- Language
- en
- Open access
- hybrid
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