Cited by 11Hepatitis C virus researchCoenzyme Q10 studies and effectsDrug-Induced Hepatotoxicity and Protection

847 phase II study of the mitochondrial antioxidant mitoquinone for hepatitis C

Gane, E.J., Orr, D.W., Weilert, F., Keogh, G.F., Gibson, M., Murphy, M.P., Smith, R.A., Lockhart, M.M. +2 more·2008·Journal of Hepatology

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Crossref · 10.1016/s0168-8278(08)60849-1

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Claims other papers make about this one

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  • MitoQ has been tested successfully in human diseases such as Hepatitis C induced liver disease and skin photo damage and in experimental animal models including ischemia-reperfusion, neurodegenerative diseases, diabetes, and alcohol-induced hepatosteatosis.

    “For example, Mitoquinone (MitoQ) has been tested successfully in human diseases such as Hepatitis C induced liver disease and skin photo damage as well as a number of experimental animal models including ischemia-reperfusion, neurodegenerative diseases, diabetes, and alcohol-induced hepatosteatosis [8–14].”

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Authors
Gane, E. J., Orr, D. W., Weilert, F., Keogh, G. F., Gibson, M., Murphy, M. P., Smith, R. A., Lockhart, M. M., Frampton, C. M., & Taylor, K. M.
Affiliations
  • Auckland City Hospital (NZ)
  • Waikato Hospital (NZ)
  • Shupyk National Healthcare University of Ukraine (UA)
  • National Pirogov Memorial Medical University, Vinnytsya (UA)
  • University of Otago (NZ)
Venue
Journal of Hepatology
Publisher
Elsevier BV
Published
2008-01
Volume
48
Pages
S318
ISSN
0168-8278 (ISSN-L)
OpenAlex
W1998573071
Cited by
11
References
0
Citations by year
2015: 1 · 2014: 1 · 2013: 1
FWCI
1.94
Type
journal article
Language
en
Open access
closed
Locations
Journal of Hepatology (publishedVersion)
Topics
  • Health Sciences › Medicine › Hepatology › Hepatitis C virus research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Coenzyme Q10 studies and effects
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
Keywords
mitochondrial antioxidants, hepatitis C, oxidative stress, mitochondrial damage, apoptosis, serum ALT, transaminases, HCV RNA, necroinflammation, coenzyme Q10, triphenylphosphonium cation, interferon-naive patients, drug safety and tolerability, antiviral therapy, liver enzymes, fibrosis

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