The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Role of Albendazole in Programmes to Eliminate Lymphatic Filariasis
Abstract
Citing earlier advances in the treatment of lymphatic filariasis [particularly the effectiveness of single-dose diethylcarbamazine (DEC) in reducing microfilaraemia and its enhanced effectiveness when co-administered with single-dose ivermectin], Eric Ottesen, Mahroof Ismail and John Horton consider recent studies on the antifilarial activity of albendazole that have led to the current recommendations for its use in single-dose regimens in conjunction with either DEC or ivermectin for large-scale control/elimination programmes. Furthermore, the potential of albendazole as a macrofilaricide for treating individual patients with lymphatic filarial infections is emphasized as one of a number of important research questions that remain to be explored.
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In the citing paper
“2-drug treatment with DEC and ivermectin both in single doses was shown to be more effective than treatment with either drug alone, yielding up to 99% clearance of microfilaremia up to 1 year after treatment [192,193]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [192]
In the citing paper
“significant concerns remained (severe side reactions, even fatal, occur due to DEC), and DEC made any multidrug regimen unsafe for community-wide use in Africa or elsewhere onchocerciasis or loiasis might coexist with bancroftian filariasis [192]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [192]
In the citing paper
“The use of albendazole (400 mg in single dose) in combination with either ivermectin (150–200 μg/kg) or DEC (6 mg/kg) in single doses was found to be equally effective as DEC in combination with ivermectin against W. bancrofti infection in Africa or elsewhere in the world [192,199]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [192]
Citations
Cites
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Sorted by citations
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286
Metadata
- Authors
- Ottesen, E. A., Ismail, M. M., & Horton, J.
- Affiliations
- World Health Organization (CH)
- University of Colombo (LK)
- Corresponding author
- Ottesen, E.A.
- ORCID
- Horton, J.
- Venue
- Parasitology Today
- Publisher
- Elsevier BV
- Published
- 1999-09
- Volume
- 15
- Issue
- 9
- Pages
- 382-386
- ISSN
- 0169-4758 (ISSN-L)
- OpenAlex
- W2003861955
- Cited by
- 221
- References
- 2
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 8 · 2020: 2 · 2019: 2 · 2018: 8 · 2017: 5 · 2016: 5 · 2015: 5 · 2014: 5 · 2013: 4 · 2012: 8
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Parasitology Today (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Life Sciences › Immunology and Microbiology › Parasitology › Helminth infection and control
- Keywords
- albendazole, lymphatic filariasis, diethylcarbamazine, ivermectin, single-dose regimen, antifilarial activity, mass drug administration
- MeSH terms
- Animals, Diethylcarbamazine, Elephantiasis, Filarial, Filaricides, Humans, Ivermectin, Male, Microfilariae, Patient Compliance, Public Health, Wuchereria bancrofti, Albendazole, Brugia malayi
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