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Topical photodynamic therapy for patients with therapy-resistant lesions of cutaneous T-cell lymphoma
Abstract
Photodynamic therapy after topical application of 5-aminolevulinic acid is an effective therapy for nonmelanoma epithelial skin cancers. It has also been used for some cases of cutaneous T-cell lymphoma. We treated 4 patients with different cutaneous T-cell lymphomas with photodynamic therapy. Those patients had previously reached a partial remission with more conventional therapies, but single lesions had remained. In all of these cases a complete remission of these lesions was achieved. We, therefore, suggest that photodynamic therapy can be a useful additional treatment modality for patients with therapy-resistant lesions of cutaneous T-cell lymphoma.
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“On the other hand, in the treatment of cutaneous T cell lymphoma Coors and colleagues were able to achieve 100% response with no recurrence after 18 months [115].”
From Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer (2011) · cites this paper as [115]
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References 19 · Cited by 74
Research works printed but not linked: 16
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Metadata
- Authors
- Coors, E. A., & von den Driesch, P.
- Affiliations
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Corresponding author
- Coors, Esther A
- Venue
- Journal of the American Academy of Dermatology
- Publisher
- Elsevier BV
- Published
- 2004-03
- Volume
- 50
- Issue
- 3
- Pages
- 363-367
- ISSN
- 0190-9622 (ISSN-L)
- OpenAlex
- W2132033669
- Cited by
- 74
- References
- 19
- Citations by year
- 2025: 3 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 2 · 2013: 7 · 2012: 4
- FWCI
- 7.43
- Type
- journal article
- Language
- en
- Update notices
- erratum (2004-06-01)
- Open access
- closed
- Locations
- Journal of the American Academy of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Cutaneous lymphoproliferative disorders research
- Health Sciences › Medicine › Dermatology › Nonmelanoma Skin Cancer Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Photodynamic Therapy Research Studies
- Keywords
- photodynamic therapy, cutaneous T-cell lymphoma, 5-aminolevulinic acid, localized lymphoma, complete remission, adjunctive therapy
- MeSH terms
- Administration, Topical, Adult, Aged, Aminolevulinic Acid, Female, Humans, Male, Middle Aged, Photochemotherapy, Skin Neoplasms, Lymphoma, T-Cell, Drug Resistance, Neoplasm
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- Coors, E. A., & von den Driesch, P. (2004). Topical photodynamic therapy for patients with therapy-resistant lesions of cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology. https://doi.org/10.1016/s0190-9622(03)00868-5