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Cited by 202Prostate Cancer Diagnosis and TreatmentSexual function and dysfunction studiesUrinary Bladder and Prostate Research

The DOI matches its Crossref record; 56 of the 57 references it cites were found in a registry or an index.

Meta-analysis of rates of erectile function after treatment of localized prostate carcinoma

Robinson, John W, Moritz, Sabine, Fung, Tak·2002·International Journal of Radiation Oncology*Biology*Physics
DOI 10.1016/s0360-3016(02)03030-4
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Abstract

Purpose The results of a 1997 meta-analysis of the rates of erectile function after external beam radiotherapy (EBRT) and radical prostatectomy have been widely used in patient and professional education materials and as a reference against which new findings are compared. With a number of recent publications, it is now possible to update this analysis and compare brachytherapy with or without EBRT with EBRT alone, standard and nerve-sparing radical prostatectomy, and cryotherapy.Methods A comprehensive literature review and subsequent meta-analysis of the rates of erectile dysfunction associated with the treatments of localized prostate carcinoma was conducted. A simple logistic regression analysis was used to combine the data from the 54 articles that met the selection criteria.Results The predicted probability of maintaining erectile function after brachytherapy was 0.76, after brachytherapy plus EBRT 0.60, after EBRT 0.55, after nerve-sparing radical prostatectomy 0.34, after standard radical prostatectomy 0.25, and after cryotherapy 0.13. When only studies reporting > or = 2 years follow-up were considered, the only significant change was a decline in the probability for nerve-sparing radical prostatectomy. No brachytherapy studies had a follow-up of > or = 2 years. When the probabilities were adjusted for age, the spread between the RT methods and surgical approaches was greater.Conclusion The differences in the probability of maintaining erectile function after different treatments of localized prostate cancer are significant.

Overview

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Crossref · 10.1016/s0360-3016(02)03030-4

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56 of 56 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 7

  1. 1997, Salpine Health Network, Radiation beats surgery for preserving sexual function
  2. 1997, Keep it up, Prevention Magazine, 62
  3. Blank, 1999, Neoadjuvant androgen deprivation prior to transperineal prostate brachytherapy, Cancer J Sci Am, 5, 370
  4. Fleming, 1993, A decision analysis of alternative treatment strategies for clinically localized prostate cancer, JAMA, 269, 2650, 10.1001/jama.1993.03500200064035 · DOI · Paper page
  5. Bruner, 1997, Sexual function after radiotherapy plus or minus androgen deprivation for clinically localized prostate cancer in younger men (age 50–65), Oncol Nurs Forum, 24, 327
  6. Mantz, 1999, Potency preservation following conformal radiotherapy for localized prostate cancer, Cancer J Sci Am, 5, 230
  7. Klotz, 2000, A randomized phase 3 study of intraoperative cavernous nerve stimulation with penile tumescence monitoring to improve nerve sparing during radical prostatectomy, J Urol, 164, 1573, 10.1016/S0022-5347(05)67031-0 · DOI

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Metadata

Authors
Robinson, J. W., Moritz, S., & Fung, T.
Affiliations
University of Calgary (CA)
Corresponding author
Robinson, John W
ORCID
Fung, Tak
Venue
International Journal of Radiation Oncology*Biology*Physics
Publisher
Elsevier BV
Published
2002-11
Volume
54
Issue
4
Pages
1063-1068
ISSN
0360-3016 (ISSN-L)
DOI
10.1016/s0360-3016(02)03030-4
OpenAlex
W2158090738
Cited by
202
References
57
Citations by year
2025: 3 · 2023: 5 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 8 · 2018: 8 · 2017: 11 · 2016: 7 · 2015: 4 · 2014: 10 · 2013: 19 · 2012: 18
FWCI
2.01
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • International Journal of Radiation Oncology*Biology*Physics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Urology › Prostate Cancer Diagnosis and Treatment
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
Keywords
erectile dysfunction, localized prostate cancer, brachytherapy, external beam radiotherapy, nerve-sparing radical prostatectomy, radical prostatectomy, cryotherapy, erectile function preservation, treatment comparison
MeSH terms
Aged, Brachytherapy, Humans, Erectile Dysfunction, Male, Middle Aged, Penile Erection, Probability, Prostatectomy, Prostatic Neoplasms

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