Transformation maligne d’une endométriose pariétale
Abstract
Cancer arising in abdominal wall endometriosis is a rare event, hindering diagnosis and making management uncertain. A cesarean section scar is generally at the origin of the disease. We report the case of a 45-year-old woman, with a past medical history of cesarean deliveries, complaining of a repeat abdominal wall endometriosis which transformed into a clear-cell carcinoma. Outcome was rapidly fatal. Compared with endometriosis-associated ovarian carcinoma, the prognosis of this abdominal scar complication is poor. In the literature, survival rate reaches only 57% after a short follow-up of 20 months. Clear-cell carcinoma is the most common histological subtype, followed by endometrioid carcinoma. Radical surgery is the main treatment. Good technique and proper care during cesarean section may help in preventing this endometriosis complication.
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The combination of carboplatin (AUC 5-6) and paclitaxel (175mg/m2) used for six cycles demonstrates efficacy in treatment, and this combination is better tolerated and less toxic compared to the use of doxorubicin, carboplatin, and paclitaxel triple therapy.
“The combination of carboplatin (AUC 5-6) and paclitaxel (175mg/m2) used for six cycles demonstrates efficacy in treatment, and this combination is better tolerated and less toxic compared to the use of doxorubicin, carboplatin, and paclitaxel triple therapy [8, 25, 26].”
From Clear cell carcinoma arising from abdominal wall endometriosis—A report on two cases and literature review (2022) · cites this paper as [26]
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References 19 · Cited by 57
- Authors
- Sergent, F., Baron, M., Le Cornec, J.-B., Scotté, M., Mace, P., & Marpeau, L.
- Affiliations
- Hôpital Charles-Nicolle (FR)
- Corresponding author
- Sergent, F.
- Venue
- Journal de Gynécologie Obstétrique et Biologie de la Reproduction
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 35
- Issue
- 2
- Pages
- 186-190
- ISSN
- 0150-9918 (ISSN-L)
- 0368-2315
- OpenAlex
- W83504608
- Cited by
- 57
- References
- 19
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 5 · 2016: 2 · 2015: 3 · 2014: 4 · 2013: 6 · 2012: 5
- FWCI
- 3.53
- Type
- journal article
- Language
- fr
- Open access
- closed
- Locations
- Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Health Sciences › Medicine › Reproductive Medicine › Ovarian cancer diagnosis and treatment
- Keywords
- abdominal wall endometriosis, malignant transformation, clear cell carcinoma, endometrioid carcinoma, cesarean section scar, cesarean section technique, endometriosis-associated ovarian cancer, radical surgery, prognosis, survival
- MeSH terms
- Abdominal Neoplasms, Adenoma, Cell Transformation, Neoplastic, Cesarean Section, Cicatrix, Endometriosis, Female, Humans, Magnetic Resonance Imaging, Middle Aged, Prognosis, Abdominal Wall
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