The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Hydrogel membranes with mesh size asymmetry based on the gradient crosslinking of poly (vinyl alcohol)
Open accessAbstract
Poly(vinyl alcohol) (PVA) hydrogel membranes with mesh size asymmetry were prepared and their transport properties were studied. Homogeneous membranes with water contents of 82%, 76% and 72% were prepared by crosslinking PVA with glutaraldehyde. These membranes were then modified to create asymmetry by establishing a glutaraldehyde concentration gradient across the hydrogel thickness. The reaction time and magnitude of the glutaraldehyde concentration gradient were varied to determine the optimum values of permeability and selectivity. Permeation experiments with creatinine, Fab and IgG were performed in a stirred diffusion cell through homogeneous and asymmetric PVA hydrogels. A modified version of the multiple-membrane technique was used to determine boundary layer resistance in order to determine the intrinsic membrane permeability. As expected, the selectivity of creatinine over IgG increased as the modification time increased. However, the selectivity of Fab over IgG initially increased as the modification time increased, but then decreased at longer times, indicating that the increased crosslinking at the surface effectively blocks both proteins. At a given value of IgG rejection, the asymmetric membranes had higher creatinine and Fab permeabilities than the corresponding homogeneous membranes. This indicates that creating mesh size asymmetry in a hydrogel can result in a high-flux, high-selectivity membrane for cell encapsulation or bioseparations.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Glutaraldehyde (GA) can be used for crosslinking polymer containing –OH functional group.19,20”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Marshall, A. D., Munro, P. A., & Trägårdh, G. (1993) · Desalination · doi:10.1016/0011-9164(93)80047-q · Cited by 467
Antibody diffusion in human cervical mucus
Saltzman, W. M., Radomsky, M. L., Whaley, K. J., & Cone, R. A. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80802-1 · Cited by 381
Bioengineering in Development of the Hybrid Artificial Pancreas
Colton, C. K., & Avgoustiniatos, E. S. (1991) · Journal of Biomechanical Engineering · doi:10.1115/1.2891229 · Cited by 215
Transport characterization of membranes for immunoisolation
Dionne, K. E., Cain, B. M., Li, R. H., Bell, W. J., Doherty, E. J., Rein, D. H., Lysaght, M. J., & Gentile, F. T. (1996) · Biomaterials · doi:10.1016/0142-9612(96)85563-3 · Cited by 105
Solute diffusion in swollen membranes
Peppas, M. L. B. A. N. A. (1987) · Journal of Membrane Science · doi:10.1016/s0376-7388(00)85001-2 · Cited by 102
Transport of proteins through gel-filled porous membranes
Kapur, V., Charkoudian, J. C., & Anderson, J. L. (1997) · Journal of Membrane Science · doi:10.1016/s0376-7388(97)00037-9 · Cited by 65
Selective permeability of PVA membranes. II. Heat-treated membranes
Katz, M. G., & Wydeven, T. L. (1982) · Journal of Applied Polymer Science · doi:10.1002/app.1982.070270109 · Cited by 65
Selective permeability of PVA membranes. I. Radiation‐crosslinked membranes
Katz, M. G., & Wydeven, T. L. (1981) · Journal of Applied Polymer Science · doi:10.1002/app.1981.070260910 · Cited by 56
Shoichet, M. S., Winn, S. R., Gentile, F. T., Athavale, S., & Harris, J. M. (1994) · Biotechnology and Bioengineering · doi:10.1002/bit.260430705 · Cited by 56
Permeability and biocompatibility of a new hydrogel used for encapsulation of hepatocytes
Honiger, J., Balladur, P., Mariani, P., Calmus, Y., Vaubourdolle, M., Delelo, R., Capeau, J., & Nordlinger, B. (1995) · Biomaterials · doi:10.1016/0142-9612(95)99637-2 · Cited by 55
Dextran permeation through poly(N-isopropylacrylamide) Hydrogels
Dong, L. C., Hoffman, A. S., & Qi, Y. (1994) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856294x00158 · Cited by 46
Li, R., & Barbari, T. A. (1994) · Journal of Membrane Science · doi:10.1016/0376-7388(93)e0182-j · Cited by 30
Self-citationReverse osmosis separation of inorganic salts using polyvinylalcohol membranes
Chang, H. N. (1982) · Desalination · doi:10.1016/s0011-9164(00)88742-1 · Cited by 27
Refractive Keratoplasty with Synthetic Lens Implants
McCarey, B. E. (1991) · International Ophthalmology Clinics · doi:10.1097/00004397-199103110-00012 · Cited by 19
Li, R., & Barbari, T. A. (1996) · Journal of Membrane Science · doi:10.1016/0376-7388(95)00296-0 · Cited by 10
Self-citation
Research works printed but not linked: 3
- R.H. Li, Surface-modified Hydrogel-based Membranes for Bioseparations, Ph.D. Dissertation, Department of Chemical Engineering, The Johns Hopkins University, 1994
- Colton, 1970, Diffusion of organic solutes in stagnant plasma and red cell suspension, Chem. Eng. Progr. Symp., 66, 85
- J. Crank, Mathematics of Diffusion, Oxford University Press, London, 1956
Cited by
Sorted by citations
Hydrogels for Tissue Engineering
Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,295
Surface Modifications for Antifouling Membranes
Rana, D. K., & Matsuura, T. (2010) · Chemical Reviews · doi:10.1021/cr800208y · Cited by 2,165
Novel crosslinking methods to design hydrogels
Hennink, W. E., & van Nostrum, C. F. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00240-x · Cited by 2,009
Hydrogels and Hydrogel-Derived Materials for Energy and Water Sustainability
Guo, Y., Bae, J., Fang, Z., Li, P., Zhao, F., & Yu, G. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00345 · Cited by 1,418
Soft Materials by Design: Unconventional Polymer Networks Give Extreme Properties
Zhao, X., Chen, X., Yuk, H., Lin, S., Liu, X., & Parada, G. A. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01088 · Cited by 1,177
Metadata
- Authors
- Dai, W. S., & Barbari, T. A.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Barbari, T.A
- Venue
- Journal of Membrane Science
- Publisher
- Elsevier BV
- Published
- 1999-04
- Volume
- 156
- Issue
- 1
- Pages
- 67-79
- ISSN
- 0376-7388 (ISSN-L)
- OpenAlex
- W1971550603
- Cited by
- 142
- References
- 15
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 10 · 2020: 7 · 2019: 4 · 2018: 7 · 2017: 7 · 2016: 4 · 2015: 5 · 2014: 8 · 2013: 5 · 2012: 9
- FWCI
- 1.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Membrane Science (publishedVersion, cc-by-nc-nd)
- Funders
- National Science Foundation (9320538)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Chemical Engineering › Filtration and Separation › Membrane Separation and Gas Transport
- Physical Sciences › Environmental Science › Water Science and Technology › Membrane Separation Technologies
- Keywords
- polyvinyl alcohol hydrogel, glutaraldehyde crosslinking, asymmetric membranes, membrane permeability, membrane selectivity, boundary layer resistance, cell encapsulation, bioseparation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
