The DOI matches its Crossref record.
Computer-assisted high-performance liquid chromatography method development with applications to the isolation and analysis of phytoplankton pigments
Abstract
We used chromatography modeling software to assist in HPLC method development, with the goal of enhancing separations through the exclusive use of gradient time and column temperature. We surveyed nine stationary phases for their utility in pigment purification and natural sample analysis. For purification, a complex algal matrix was separated on an efficient monomeric column, from which partially purified fractions were collected and purified on polymeric columns that exaggerated resolution between pigments of interest. Additionally, we feature an HPLC method that is simple, fast, demonstrates excellent transferability and is ideal for quantitative analysis of pigments in dilute natural water samples.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Improving photosynthesis and crop productivity by accelerating recovery from photoprotection
Kromdijk, J., Głowacka, K., Leonelli, L., Gabilly, S. T., Iwai, M., Niyogi, K. K., & Long, S. P. (2016) · Science · doi:10.1126/science.aai8878 · Cited by 1,317
Patterns and ecological drivers of ocean viral communities
Brum, J. R., Ignacio-Espinoza, J. C., Roux, S., Doulcier, G., Acinas, S. G., Alberti, A., Chaffron, S., Cruaud, C., de Vargas, C., Gasol, J. M., et al. (2015) · Science · doi:10.1126/science.1261498 · Cited by 785
Safafar, H., Van Wagenen, J., Møller, P., & Jacobsen, C. (2015) · Marine Drugs · doi:10.3390/md13127069 · Cited by 478
Global Trends in Marine Plankton Diversity across Kingdoms of Life
Ibarbalz, F. M., Henry, N., Brandão, M. C., Martini, S., Busseni, G., Byrne, H., Coelho, L. P., Endo, H., Gasol, J. M., Gregory, A. C., et al. (2019) · Cell · doi:10.1016/j.cell.2019.10.008 · Cited by 473
Photosynthetic pigments in diatoms
Kuczynska, P., Jemiola-Rzeminska, M., & Strzalka, K. (2015) · Marine Drugs · doi:10.3390/md13095847 · Cited by 428
Metadata
- Authors
- Van Heukelem, L., & Thomas, C. S.
- Venue
- Journal of Chromatography A
- Publisher
- Elsevier BV
- Published
- 2001-02
- Volume
- 910
- Issue
- 1
- Pages
- 31-49
- ISSN
- 0021-9673 (ISSN-L)
- OpenAlex
- W2112412743
- Cited by
- 823
- References
- 0
- FWCI
- 3.43
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Computer-assisted high-performance liquid chromatography method development with applications to the isolation and analysis of phytoplankton pigments. https://app.cochat.ai/papers/10.1016/s0378-4347(00)00603-4
- The paper
- Van Heukelem, L., & Thomas, C. S. (2001). Computer-assisted high-performance liquid chromatography method development with applications to the isolation and analysis of phytoplankton pigments. Journal of Chromatography A. https://doi.org/10.1016/s0378-4347(00)00603-4
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
