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Cited by 320Essential Oils and Antimicrobial ActivityPlant chemical constituents analysisEdible Oils Quality and Analysis

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

GC/MS evaluation of thyme (Thymus vulgaris L.) oil composition and variations during the vegetative cycle

Hudaib, Mohammad, Speroni, Ester, Di Pietra, Anna Maria, Cavrini, Vanni·2002·Journal of Pharmaceutical and Biomedical Analysis
DOI 10.1016/s0731-7085(02)00119-x
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Abstract

Capillary GC/MS analysis based on polar and non-polar columns has been applied to evaluation of the volatile oils hydrodistilled from thyme (Thymus vulgaris L.) plants. The adopted methodology has been used to monitor seasonal variations in the composition of the oil obtained from thyme herbs harvested at different periods during the plant vegetative and life cycles. Oils from thyme plants of young (2 years) and old (5 years) cultivations have been evaluated from four and two collections, respectively, effected throughout May/December growth period. Generally, the oil was found to be rich in the active monoterpene phenols (thymol and carvacrol) and their corresponding monoterpene hydrocarbon (HC) precursors (p-cymene and gamma-terpinene), which collectively showed synchronized patterns of variation during the different collection periods and in different seasons. The oil from old plant collected in May/June period (0.15% v/w) was characterized by significantly lower levels of monoterpene HCs (mainly gamma-terpinene) and the highest levels of the oxygenated monoterpenes (linalool and borneol), monoterpene phenols (mainly thymol) and their derivatives (mainly carvacrol methyl ether), sesquiterpenes (mainly beta-caryophyllene) and their oxygenated derivatives (e.g. caryophyllene oxide) in comparison with all other samples. A characteristic presence of camphor and thymodihydroquinone was also observed in the old plant oils. On the other hand, the young plant, collected in June/July just before the end of the vegetative cycle, provided the best oil yield (1.2%) with also the highest % content of the monoterpene phenols (thymol: 51.2% and carvacrol: 4%). This latter growth period can represent the best harvest time of young thyme plants in order to obtain an essential oil with better quality and quantity.

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Crossref · 10.1016/s0731-7085(02)00119-x

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Citations

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Show all 21 references

Research works printed but not linked: 7

  1. de Bouchberg, 1976, Rivista Ital., 58, 527
  2. Granger, 1963, La France et ses parfums, 225
  3. Weiss, 1970, Pharm. Acta Helv., 45, 169
  4. Carawya, 1974, JAOAC, 57, 997
  5. Soulier, 1995, Les cahiers d'Aromathérapie (Aromather. Records), 1, 38
  6. Abasini, 1984, Atti Soc. Nat. Mat. di Modena, 115, 1
  7. Rovesti, 1971, Parf. Cosm. Sav. France, 1, 139

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Metadata

Authors
Hudaib, M., Speroni, E., Di Pietra, A. M., & Cavrini, V.
Affiliations
University of Bologna (IT)
Corresponding author
Hudaib, Mohammad
ORCID
Hudaib, Mohammad
Venue
Journal of Pharmaceutical and Biomedical Analysis
Publisher
Elsevier BV
Published
2002-07
Volume
29
Issue
4
Pages
691-700
ISSN
0731-7085 (ISSN-L)
DOI
10.1016/s0731-7085(02)00119-x
OpenAlex
W2064470344
Cited by
320
References
21
Citations by year
2026: 8 · 2025: 17 · 2024: 18 · 2023: 16 · 2022: 15 · 2021: 23 · 2020: 23 · 2019: 12 · 2018: 13 · 2017: 15 · 2016: 18 · 2015: 18 · 2014: 18 · 2013: 16 · 2012: 16
FWCI
8.48
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Pharmaceutical and Biomedical Analysis (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant chemical constituents analysis
  • Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Keywords
thyme, essential oil composition, seasonal variation, vegetative cycle, thymol, carvacrol, monoterpene phenols, monoterpene hydrocarbons, γ-terpinene, p-cymene, linalool, borneol, sesquiterpenes, caryophyllene oxide, harvest time, plant age
MeSH terms
Gas Chromatography-Mass Spectrometry, Plant Oils, Plant Stems, Thymus Plant

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