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Cited by 128Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmiasCardiovascular and exercise physiology

Exercise: A risk for sudden death in patients with coronary heart disease

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Cobb, Leonard A., Weaver, W. Douglas·1986·Journal of the American College of Cardiology
DOI 10.1016/s0735-1097(86)80284-4
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Abstract

Although sudden arrhythmic death is usually unrelated to exertion, there is more than anecdotal evidence that strenuous exercise in patients with coronary heart disease carries an additional risk for sudden death. When cardiac arrest has been observed after exercise stress testing or within seconds after collapse associated with exertion, ventricular fibrillation has usually been present and has responded to the prompt application of a defibrillatory shock. Exertion-related cardiac arrest is typically a "primary" arrhythmic event not due to acute myocardial infarction. As estimated here, the additional risk of exercise for cardiac arrest may be more than 100-fold during or after a few minutes of vigorous exertion.

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  • Several studies have estimated the relative risk of sudden death from cardiac causes to be between 5 and 100 during periods of heavy physical exertion.

    “several studies17-20 have estimated the relative risk of sudden death from cardiac causes to be between 5 and 100 during periods of heavy physical exertion.”

    From Triggering of Acute Myocardial Infarction by Heavy Physical Exertion -- Protection against Triggering by Regular Exertion (1993) · cites this paper as [19]

    The section “Exertion-Related Cardiac Arrest in Persons Without Evident Heart Disease” reports one study estimating a 5- to 56-fold higher incidence of cardiac arrest during high-intensity exercise. The “Incidence of Exertion-Related Cardiac Arrest” section also reports an approximately 10-fold difference in death rates for jogging versus nonvigorous activity. These support an elevated risk, but our copy does not document a 100-fold estimate of sudden cardiac death. (LLM, conf=0.84)

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Cites

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Research works printed but not linked: 31

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Cited by

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Authors
Cobb, L. A., & Weaver, W. D.
Affiliations
University of Washington (US)
Corresponding author
Cobb, Leonard A.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
1986-01
Volume
7
Issue
1
Pages
215-219
ISSN
0735-1097 (ISSN-L)
DOI
10.1016/s0735-1097(86)80284-4
OpenAlex
W2026409998
Cited by
128
References
1
Citations by year
2023: 1 · 2022: 5 · 2021: 3 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 5 · 2014: 2 · 2013: 3 · 2012: 4
FWCI
1.29
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
American Heart Association
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
sudden cardiac death, coronary artery disease, exercise risk, cardiac arrest, ventricular fibrillation, exercise stress testing, defibrillation
MeSH terms
Adult, Aged, Coronary Disease, Death, Sudden, Exercise Test, Exercise Therapy, Physical Exertion, Heart Arrest, Heart Diseases, Humans, Male, Middle Aged, Risk, Ventricular Fibrillation

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