Gain Modulation
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Head-restrained preparations have shown that behavioral state fluctuations have a strong impact on neuronal gain and coding properties in primary sensory areas and modulate neuronal firing within brain-wide neuronal networks.
“By employing head-restrained preparations, a growing body of work has demonstrated that behavioral state fluctuations have a strong impact on neuronal gain and coding properties in primary sensory areas36,43,66–70 and modulate neuronal firing within brain-wide neuronal networks44,71–74.”
From Place and behavioral modulation of hippocampal neurons during immobility (2026) · cites this paper as [71]
Gain-modulated cells are suited to perform multimodal computations, such as conversions from sensory-centred into motor-centred reference frames, and for the generation of invariant responses to input features despite contextual variability.
“Gain-modulated cells are ideally suited to perform multimodal computations, such as conversions from sensory-centred into motor-centred reference frames, and for the generation of invariant responses to input features despite contextual variability6–9.”
From Mechanisms underlying gain modulation in the cortex (2020) · cites this paper as [6]
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References 68 · Cited by 400
- Authors
- Salinas, E., & Thier, P.
- Affiliations
- Salk Institute for Biological Studies (US)
- University of Tübingen (DE)
- Corresponding author
- Salinas, Emilio
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2000-07
- Volume
- 27
- Issue
- 1
- Pages
- 15-21
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W23745746
- Cited by
- 400
- References
- 68
- Citations by year
- 2026: 14 · 2025: 12 · 2024: 13 · 2023: 14 · 2022: 21 · 2021: 15 · 2020: 27 · 2019: 14 · 2018: 17 · 2017: 13 · 2016: 15 · 2015: 17 · 2014: 15 · 2013: 20 · 2012: 19
- FWCI
- 4.41
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- gain modulation, neural computation, neural representations, neural coding
- MeSH terms
- Algorithms, Animals, Central Nervous System, Humans, Nervous System Physiological Phenomena, Neurons, Visual Fields
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