The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Intranuclear Neuronal Inclusions: A Common Pathogenic Mechanism for Glutamine-Repeat Neurodegenerative Diseases?
Open accessAbstract
Eight progressive neurodegenerative disorders, including Huntington's disease (HD) and several forms of spinocerebellar ataxia (SCA; see Table 1), are currently known to be caused by expanding CAG-triplet repeats coding for polyglutamine (Ross 1995; Andrew et al. 1997; Gusella et al. 1997). The genes causing these degenerative disorders show no homology to each other outside of the glutamine repeat, and most are genes of unknown function. In each of these diseases, an overlapping but distinct set of cortical and subcortical regions is affected. However, although the genes for the disorders are expressed widely throughout the brain, and also in peripheral tissues, only certain populations of neurons degenerate. The mechanism for this selective neuronal death has remained puzzling.
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Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G. P., Davies, S. W., Lehrach, H., & Wanker, E. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80514-0 · Cited by 1,291
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Gutekunst, C.-A., Li, S.-H., Yi, H., Mulroy, J. S., Kuemmerle, S., Jones, R., Rye, D., Ferrante, R. J., Hersch, S. M., & Li, X.-J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02522.1999 · Cited by 914
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Expanded Polyglutamine Protein Forms Nuclear Inclusions and Causes Neural Degeneration in Drosophila
Warrick, J. M., Paulson, H. L., Gray-Board, G. L., Bui, Q. T., Fischbeck, K. H., Pittman, R. N., & Bonini, N. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81200-3 · Cited by 668
Metadata
- Authors
- Ross, C. A.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1997-12
- Volume
- 19
- Issue
- 6
- Pages
- 1147-1150
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2039376206
- Cited by
- 388
- References
- 1
- FWCI
- 13.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Ross, C. A. (1997). Intranuclear Neuronal Inclusions: A Common Pathogenic Mechanism for Glutamine-Repeat Neurodegenerative Diseases? Neuron. https://doi.org/10.1016/s0896-6273(00)80405-5
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