Pattern of Brachyury gene expression in starfish embryos resembles that of hemichordate embryos but not of sea urchin embryos
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Echinoderms, hemichordates and chordates are deuterostomes and share a number of developmental features. The Brachyury gene is responsible for formation of the notochord, the most defining feature of chordates, and thus may be a key to understanding the origin and evolution of the chordates. Previous studies have shown that the ascidian Brachyury (As-T and Ci-Bra) is expressed in the notochord and that a sea urchin Brachyury (HpTa) is expressed in the secondary mesenchyme founder cells. A recent study by [Tagawa et al. (1998)], however, revealed that a hemichordate Brachyury (PfBra) is expressed in a novel pattern in an archenteron invagination region and a stomodaeum invagination region in the gastrula. The present study demonstrated that the expression pattern of Brachyury (ApBra) of starfish embryos resembles that of PfBra in hemichordate embryos but not of HpTa in sea urchin embryos. Namely, ApBra is expressed in an archenteron invagination region and a stomodaeum invagination region.
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Hemichordate and echinoderm dipleurula larvae both express Brachyury in the oral and anal regions of the larval gut.
“Thus both hemichordate and echinoderm dipleurula larvae express the Brachyury gene in the oral and anal regions of the larval gut.”
From Bilaterian Origins: Significance of New Experimental Observations (2000) · cites this paper as Shoguchi et al., 1999
All deuterostome dipleurula larvae share significant similarities.
“The notion that significant similarities are shared by all deuterostome dipleurula larvae is further supported by new studies on Brachyury expression in enteropneust hemichordates”
From Bilaterian Origins: Significance of New Experimental Observations (2000) · cites this paper as Shoguchi et al., 1999
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References 15 · Cited by 95
Research works printed but not linked: 1
- Dan, K., 1983. Chapter 1, Review (in Japanese). In: Dan, K. et al. (Eds.), Development of Invertebrates. Baifukan, Tokyo, pp. 1-49.
- Authors
- Shoguchi, E., Satoh, N., & Maruyama, Y. K.
- Affiliations
- Kyoto University (JP)
- Corresponding author
- Shoguchi, Eiichi
- Venue
- Mechanisms of Development
- Publisher
- Elsevier BV
- Published
- 1999-04
- Volume
- 82
- Issue
- 1-2
- Pages
- 185-189
- ISSN
- 0925-4773 (ISSN-L)
- OpenAlex
- W2052246603
- Cited by
- 95
- References
- 15
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2013: 1 · 2012: 4
- FWCI
- 3.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Mechanisms of Development (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Human Frontier Science Program (RG212/1997)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Marine Invertebrate Physiology and Ecology
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Echinoderm biology and ecology
- Keywords
- Brachyury, starfish embryos, sea urchin embryo, gene expression patterns, notochord, chordate evolution, deuterostomes
- MeSH terms
- Brachyury Protein, Amino Acid Sequence, Animals, Base Sequence, Chordata, Nonvertebrate, DNA-Binding Proteins, Fetal Proteins, Larva, Molecular Sequence Data, Phylogeny, Sea Urchins, Species Specificity, Starfish, Transcription Factors, DNA Primers, Gene Expression Regulation, Developmental, T-Box Domain Proteins
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