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Adhesion events in angiogenesis
Abstract
Recent work from several laboratories indicates that the coordination of endothelial cell adhesion events with growth factor receptor inputs regulates endothelial cell responses during angiogenesis. Analyses of the signaling pathways downstream of integrins, cadherins and growth-factor receptors are providing an insight into the molecular basis of known anti-angiogenic strategies, as well as into the design of novel therapies.
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“The lack of angiogenesis could also be due to the inability of the endothelial cells to adhere to each other and form tubes [66].”
From Tobacco toxins deposited on surfaces (third hand smoke) impair wound healing (2016) · cites this paper as [66]
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Metadata
- Authors
- Eliceiri, B. P., & Cheresh, D. A.
- Affiliations
- Scripps Research Institute (US)
- Corresponding author
- Cheresh, David A
- Venue
- Current Opinion in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2001-10
- Volume
- 13
- Issue
- 5
- Pages
- 563-568
- ISSN
- 0955-0674 (ISSN-L)
- OpenAlex
- W2103963843
- Cited by
- 287
- References
- 68
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 4 · 2016: 7 · 2015: 5 · 2014: 8 · 2013: 13 · 2012: 7
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- National Institutes of Health
- National Cancer Institute (CA-50286, CA-45726, R01CA045726, CA 78045, P01CA078045)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- angiogenesis, endothelial cell adhesion, integrins, cadherins, growth factor receptors, signaling pathways, angiogenesis inhibitors
- MeSH terms
- Cell Adhesion, Endothelium, Vascular, Extracellular Matrix, Humans, Neovascularization, Pathologic, Antigens, CD, Integrins, Receptors, Growth Factor, Neovascularization, Physiologic, Angiogenesis Inhibitors, Integrin alphaV
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