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Rho family GTPases: more than simple switches

Symons, Marc, Settleman, Jeff·2000·Trends in Cell Biology
DOI 10.1016/s0962-8924(00)01832-8
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Abstract

Rho family GTPases control a large variety of biological processes. Cycling of Rho proteins between the GDP-bound and the GTP-bound state is controlled by several classes of regulatory proteins. In this review, we discuss the signal-transduction mechanisms that control these regulators. We will emphasize the subcellular localization of Rho GTPases and their regulatory proteins and the role of GTP hydrolysis in signal transmission.

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Cited by

Metadata

Authors
Symons, M., & Settleman, J.
Venue
Trends in Cell Biology
Publisher
Elsevier BV
Published
2000-10
Volume
10
Issue
10
Pages
415-419
ISSN
0962-8924
DOI
10.1016/s0962-8924(00)01832-8
Cited by
195
References
1
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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