Cited by 2,181Machine Learning in BioinformaticsProtein Structure and DynamicsGenomics and Phylogenetic Studies

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PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

Nakai, Kenta, Horton, Paul·1999·Trends in Biochemical Sciences

DOI 10.1016/s0968-0004(98)01336-x

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Research works printed but not linked: 4

Horton, 1996, Intelligent Systems for Molecular Biology, 4, 109
Horton, 1997, Intelligent Systems for Molecular Biology, 5, 147
Nakai, K.(1996) in Genome Informatics 1996 (Vol. 7) (Akutsu, T. et al.., eds), pp. 72-81, Universal Academy Press
Bairoch, 1997, Nucleic Acids Res., 25, 217, 10.1093/nar/25.1.217 · DOI

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“Several algorithms (cNLSMapper [12], PSORT II [13], NLStradamus [14], and NucPred [15]) predict a C-terminal nuclear localization sequence (NLS) in H03-IPSE close to the C terminus (data not shown), similarly to the NLS described previously for M-IPSE (16).”
BackgroundMethod
A novel leucine-rich repeat receptor-like kinase gene in potato, StLRPK1, is involved in response to diverse stresses
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“The signal peptide of the putative protein was forecasted using SignalP 3.0 Server http://www.cbs.dtu.dk/services/SignalP/ [19] and prediction of protein localization sites was performed using PSORT http://psort.ims.u-tokyo.ac.jp/form.html [ 20 ].”
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“The program P-SORT (25) predicts QDE-1 to be a nuclear protein, based on the presence of a bipartite sequence and we confirmed that this was the case by showing that FLAGQDE-1 was enriched in nuclear extracts (Figure 2A).”
Background
ifet-1 is a broad scale translational repressor required for normal P granule formation in C. elegans
Sengupta, M. S., Low, W. Y., Patterson, J. R., Kim, H., Traven, A., Beilharz, T. H., Colaiácovo, M. P., Schisa, J. A., & Boag, P. R. (2012) · Journal of Cell Science · doi:10.1242/jcs.119834 · Cited by 34
“Bioinformatics The putative bipartate NLS and NES of IFET-1 were identified using web base tools PSORT II Prediction (Nakai and Horton, 1999) (http://psort.”
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Mizuno, Y., Kurochkin, I. V., Herberth, M., Okazaki, Y., & Schönbach, C. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-s12-s16 · Cited by 36
“Yet, the performance of subcellular location predictions, for example PSORT II [17], pTARGET [18] or PTS1 predictor [19] is limited by the small number of peroxisomal training data compared to the data on nuclear, mitochondrial and cytoplasm-located proteins.”
Background
Cloning and subcellular localization of the phosphoprotein and nucleocapsid proteins of Potato yellow dwarf virus, type species of the genus Nucleorhabdovirus
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“The PSORT agorithm (Nakai and Horton, 1999) was used to predict the presence of arginine/lysine-rich NLSs in the N and P proteins of seven Nucleorhabdoviruses.”
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AtTRB1, a telomeric DNA-binding protein from Arabidopsis, is concentrated in the nucleolus and shows highly dynamic association with chromatin
Dvořáčková, M., Rossignol, P., Shaw, P., Koroleva, O., Doonan, J. H., & Fajkus, J. (2009) · The Plant Journal · doi:10.1111/j.1365-313x.2009.04094.x · Cited by 37
“PSORT prediction (Nakai and Horton, 1999) indicates a potential nuclear localization signal (NLS) at amino acid position 191 located at the end of the histone-like domain.”
Background
Cloning, Sequence Analysis, and Expression in Escherichia coli of the Gene Encoding an α-Amino Acid Ester Hydrolase from Acetobacter turbidans
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“In the carboxy-terminal segment of the leader sequence, a consensus pattern specific for the cleavage by signal peptidase I (AXA) is present (23, 24, 26).”
Left–Right Asymmetric Ventricular Expression of CARP in the Piglet Heart: Regional Response to Experimental Heart Failure
Torrado, M., López, E., Centeno, A., et al. (2004) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2003.11.004 · Cited by 36
Mammalian mitochondrial proteomics: insights into mitochondrial functions and mitochondria-related diseases
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Adenosine Metabolism, Adenosine Kinase, and Evolution
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Methodology development for predicting subcellular localization and other attributes of proteins
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“Among the aforementioned methods, some were implemented as web servers and could therefore be widely used by experimental scientists (e.g., PSort [ 7 ,201], SubLoc [20,202], PLoc [27,203], ESLpred [67,204], SignalP [68,205], pSLIP [69,206], BaCelLo [70,207]).”
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“hydrophobicity [31], hydrophilicity [27], polarity [32], polarizability [33], solvation free energy [27], graph shape index [34], transfer free energy [28], amino acid composition [35], correlation coefficient in regression analysis [36], residue accessible surface area [37], partition coefficient [38], entropy of for…”
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“All identified proteins are listed with their annotation, PSORT localization (20), numbers of peptides, intensities, and statistics information in Supporting Information Table S3.”
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“Moreover, PSORT II analysis (Nakai and Horton, 1999) identified KIFL, a KKXX-like motif known as endoplasmatic reticulum membrane retention signal at the Cterminus of both TRAIL-b and -g. PROSITE scan (Bairoch, 1991) also identified potential protein kinase C phosphorylation sites between amino…”
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“For the rest of the proteins, prediction programs such as WoLF PSORT (Horton and Nakai, 1999), TargetP (Emanuelsson et al.”
Method
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“PaxG C-terminus tripeptide GRV a peroxisomal targeting signal PaxG has the tripeptide GRV at its C-terminus that is predicted to be a variant of the PTS1 motif SKL (Gould et al. 1989; Nakai and Horton 1999).”
BackgroundMethodInfluential
Proteomic analysis of irregular, bullet‐shaped magnetosomes in the sulphate‐reducing magnetotactic bacterium Desulfovibrio magneticus RS‐1
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“The PSORT programme was used to predict the localisation sites of identified proteins [25, 26].”
Method
Serial Analysis of Gene Expression (SAGE) in the Rat Limbal and Central Corneal Epithelium
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“On the other hand, analysis of Aurora B sequence using the PSORT II program (Nakai and Horton, 1999) identified a stretch of basic residues as a putative ‘pat7’ NLS.”
Method
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“We analyzed the primary sequence of AF6/s-afadin with the PSORT II program (Nakai and Horton, 1999) and detected at least two potential nuclear localization sequences in the n-terminal region of the protein at positions 162 and 343 (Fig.”
Method
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“Identification of potential nuclear-localization signals (NLSs) was performed with PSORT (http://psort.nibb.ac.jp) (Nakai & Horton, 1999; Nakai & Kanehisa, 1992).”
Boosting multiclass learning with repeating codes and weak detectors for protein subcellular localization
Lin, C., Tsai, Y., Lin, Y.-S., et al. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm497 · Cited by 35
“(Eisenhaber and Bork, 1998; Garrels, 1996; Nakai and Horton, 1999).”
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Park, J. K., Das, T., Song, E. J., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw218 · Cited by 35
“The residues 601–648 have been annotated as the NLS for SART3 based on sequence analysis using the PSORT II (36) and cNLS Mapper (38) programs.”
Method
Characterization of a non‐mitochondrial type I phosphatidylserine decarboxylase in Plasmodium falciparum
Baunaure, F., Eldin, P., Cathiard, A. M., et al. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03822.x · Cited by 35
“However, an IKIR motif is present at the PfPSD C-terminus, as predicted by the PSORTII program (Nakai and Horton, 1999).”
Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene
Schroder, W. A., Cloonan, N., Bushell, G. R., & Sculley, T. B. (2004) · Gene · doi:10.1016/j.gene.2004.07.001 · Cited by 35
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“PSORT II (Nakai and Horton, 1999), SignalP-HMM (Nielsen et al.”
HIPK2 associates with RanBPM
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“The nearest neighbour algorithm [14] suggests a 56.”
Method
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“Moreover, predictions with PSORT (37) indicate a preferentially cytosolic location.”
Background
Two Novel Genes Induced by Hard-Surface Contact of Colletotrichum gloeosporioides Conidia
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“University), PSORTII algorithm (32), and the “hidden Markov model” (44).”
Method
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“Hybrids methods using both global and pattern information, such as PSORT II[21], may perform better.”
BackgroundMethod
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“SubLoc (9), a support-vector-based predictor using amino acid composition; and PSORT and PSORT II (10), which are based on identifying sequence motifs responsible for protein sorting, on sequence homology and on NNPSL.”
Method
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“The predicted protein seems to have no N-terminal signal peptide and is proposed to be localized in the nucleus (PSORT; Nakai & Horton, 1999).”
Background
Analysis of the subcellular localization of the human histone methyltransferase SETDB1
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Interleukin-4-Inducing Principle from Schistosoma mansoni Eggs Contains a Functional C-Terminal Nuclear Localization Signal Necessary for Nuclear Translocation in Mammalian Cells but Not for Its Uptake
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“AAK26170) was used for identification of sequence motifs such as CSS or NLS motifs by using Web-based bioinformatic tools, including Cello (57), ESLPred (6), LOCSVMPSI (56), LocTree (40), MultiLoc (26), NLSpredict (11), Proteome Analyst (51), PLOC (42), PSORTII (41), SignalP 3.0 (5), SherLoc (48), SubLoc (29), TargetP…”
BackgroundInfluential
Evolution of Mating Systems in Basidiomycetes and the Genetic Architecture Underlying Mating-Type Determination in the Yeast Leucosporidium scottii
Maia, T. M., Lopes, S., Almeida, J. M. G. C. F., Rosa, L. H., Sampaio, J. P., Gonçalves, P. M., & Coelho, M. A. (2015) · Genetics · doi:10.1534/genetics.115.177717 · Cited by 34
“Coiled-coil dimerization motifs and nuclear localization signals were identified in the complete sequences of the HD1 and HD2 proteins from both sequenced strains using, respectively, COILS (Lupas et al. 1991) and PSORTII and SeqNLS (Nakai and Horton 1999; Li and Durbin 2009).”
Method
Involvement of the Reparative DNA Polymerase Pol X of African Swine Fever Virus in the Maintenance of Viral Genome Stability In Vivo
Redrejo‐Rodríguez, M., Rodríguez, J. M., Suárez, C., Salas, J., & Salas, M. L. (2013) · Journal of Virology · doi:10.1128/jvi.01173-13 · Cited by 34
“Taking into account the small size of the Pol X protein (20 kDa) and the absence of putative nuclear localization signals in its sequence (analyzed using the NLStradamus [41] and Psort [42] servers), the observed accumulation of Pol X in the nucleus, near the end of the virus replication cycle, is likely to occur by p…”
Method
Gourds: Bitter, Bottle, Wax, Snake, Sponge and Ridge
Dhillon, N. P. S., Sanguansil, S., Singh, S. P., Masud, M. A. T., Kumar, P., Bharathi, L. K., Yetışır, H., Huang, R., Canh, D. X., & McCreight, J. D. (2016) · Plant genetics and genomics: crops and models · doi:10.1007/7397_2016_24 · Cited by 38
Proteogenomics Reveals Novel Reductive Dehalogenases and Methyltransferases Expressed during Anaerobic Dichloromethane Metabolism
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“Protein localization predictions were performed using PSORT Prediction (77).”
Method
Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection
Chakraborty, S., Randall, A. Z., Vickers, T. J., Molina, D., Harro, C. D., DeNearing, B., Brubaker, J., Sack, D. A., Bourgeois, A. L., Felgner, P. L., et al. (2019) · npj Vaccines · doi:10.1038/s41541-019-0131-7 · Cited by 34
Advances in Genome-Scale Metabolic Modeling toward Microbial Community Analysis of the Human Microbiome
Esvap, E., & Ülgen, K. Ö. (2021) · ACS Synthetic Biology · doi:10.1021/acssynbio.1c00140 · Cited by 34
Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS
Kirby, T. W., Gassman, N. R., Smith, C., Pedersen, L. C., Gabel, S. A., Sobhany, M., Wilson, S. H., & London, R. E. (2015) · Scientific Reports · doi:10.1038/srep13405 · Cited by 34
Regulation and Role of Calcium Fluxes in the Chloroplast
Johnson, C. H., Shingles, R., & Ettinger, W. F. (2007) · Advances in photosynthesis and respiration · doi:10.1007/978-1-4020-4061-0_20 · Cited by 34
“Protein sequences translated from the Arabidopsis genome were analyzed for chloroplast targeting domains using PSORT ( Nakai and Horton, 1999 ) or TargetP, (Emanuelsson et al., 2000) or for the most probable subcellular localization using ARAMEMNON (Schwacke et al., 2003).”
BackgroundMethodInfluential
Localization of human T-cell lymphotropic virus type II Tax protein is dependent upon a nuclear localization determinant in the N-terminal region
Turci, M., Romanelli, M. G., Lorenzi, P., et al. (2005) · Gene · doi:10.1016/j.gene.2005.09.043 · Cited by 34
A novel protein in Photosystem II of a diatom Chaetoceros gracilis is one of the extrinsic proteins located on lumenal side and directly associates with PSII core components
Okumura, A., Nagao, R., Suzuki, T., Yamagoe, S., Iwai, M., Nakazato, K., & Enami, I. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2008.09.004 · Cited by 34
Characterization of soluble and putative membrane-bound UDP-glucuronic acid decarboxylase (OsUXS) isoforms in rice
Suzuki, K., Watanabe, K., Masumura, T., et al. (2004) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2004.08.029 · Cited by 34
Lineage-specific gene loss following mitochondrial endosymbiosis and its potential for function prediction in eukaryotes
Gabaldón, T., & Huynen, M. (2005) · ECCB/JBI · doi:10.1093/bioinformatics/bti1124 · Cited by 36
“This investigation consisted of deeper sequence, literature and genome-context analyses, making use of several programs and databases such as STRING (von Mering et al., 2003), PubMed (http://www.ncbi.nlm.nih.gov/PubMed/), MITOP (Scharfe et al., 2000), SMART (Schultz et al., 1998), Pfam (Bateman et al., 2002) and Psort…”
Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence
dos Santos, A. P., Guimarães, A. M. S., do Nascimento, N. C., SanMiguel, P. J., Martin, S. W., & Messick, J. B. (2011) · Veterinary Research · doi:10.1186/1297-9716-42-102 · Cited by 34
“0 [33,34].”
Disruption of Oligomerization Induces Nucleocytoplasmic Shuttling of Leukemia-Associated Rho Guanine-Nucleotide Exchange Factor
Grabocka, E., & Wedegaertner, P. (2007) · Molecular Pharmacology · doi:10.1124/mol.107.035162 · Cited by 35
Chromatin regulation in schistosomes and histone modifying enzymes as drug targets
Pierce, R. J., Dubois, F., Caby, S., Trolet, J., Lancelot, J., Oger, F., Bertheaume, N., & Roger, E. (2011) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762011000700003 · Cited by 34
Toxoplasma gondiidense granule protein 3 (GRA3) is a type I transmembrane protein that possesses a cytoplasmic dilysine (KKXX) endoplasmic reticulum (ER) retrieval motif
Henriquez, F. L., Nickdel, M. B., McLeod, R. L., et al. (2005) · Parasitology · doi:10.1017/s0031182005007559 · Cited by 34
“…modification and topology predictions were analysed with the aid of a variety of prediction programs: PSORTII (http://psort.ims.u-tokyo.ac.jp) (Nakai & Horton, 1999) to predict protein sorting signals; TMHMM 2.0 (http://www.cbs.dtu.dk/services/TMHMM-2.0) (Krogh et al. 2001) to predict…”
MethodInfluential
Identification of alternatively spliced human biotinidase mRNAs and putative localization of endogenous biotinidase
Stanley, C. M., Hymes, J., & Wolf, B. (2004) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2003.12.006 · Cited by 34
Identification of a 709-Amino-Acid Internal Nonessential Region within the Essential Conserved Tegument Protein (p)UL36 of Pseudorabies Virus
Böttcher, S., Klupp, B. G., Granzow, H., Fuchs, W., Michael, K., & Mettenleiter, T. C. (2006) · Journal of Virology · doi:10.1128/jvi.01247-06 · Cited by 34
“org/prosite/) and PSORT II (27) (http://psort.”
Influential
A Human Common Nuclear Matrix Protein Homologous to Eukaryotic Translation Initiation Factor 4A
Holzmann, K., Gerner, C., Pöltl, A., et al. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1973 · Cited by 34
RNA Sequence and Two-dimensional Structure Features Required for Efficient Substrate Modification by the Saccharomyces cerevisiae RNA:Ψ-Synthase Pus7p
Urban, A., Behm‐Ansmant, I., Branlant, C., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m807986200 · Cited by 33
Prediction of midbody, centrosome and kinetochore proteins based on gene ontology information
Chen, W., & Lin, H. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.09.061 · Cited by 33
“In the last two decades, a great number of methods have been developed to predict protein localization, most of which were based on terminal signaling peptides [12,13], pseudo amino acid composition [14,15–18], dipeptide composition [19,20], functional domain composition [21,22].”
A natural antisense transcript of the fem-1 gene was found expressed in female gonads during the characterization, expression profile, and cellular localization of the fem-1 gene in Pacific white shrimp Penaeus vannamei
Galindo-Torres, P., Ventura-López, C., Llera‐Herrera, R., et al. (2019) · Gene · doi:10.1016/j.gene.2019.04.066 · Cited by 33
The Meloidogyne javanica effector Mj2G02 interferes with jasmonic acid signalling to suppress cell death and promote parasitism in Arabidopsis
Song, H., Lin, B., Huang, Q., et al. (2021) · Molecular Plant Pathology · doi:10.1111/mpp.13111 · Cited by 33
The PA‐TM‐RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis
Bocock, J. P., Carmicle, S., Chhotani, S., Ruffolo, M. R., Chu, H., & Erickson, A. H. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06913.x · Cited by 33
A diurnally regulated dehydrin from Avicennia marina that shows nucleo-cytoplasmic localization and is phosphorylated by Casein kinase II in vitro
Mehta, P. A., Rebala, K. C., Venkataraman, G., et al. (2009) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2009.03.008 · Cited by 33
The wheat chloroplastic proteome.
Kamal, A., Kun, C., Choi, J.-S., Bae, K., Komatsu, S., Uozumi, N., & Woo, S. (2013) · Journal of Proteomics · doi:10.1016/j.jprot.2013.03.009 · Cited by 32
Ecological perspectives on the sequenced genome collection
Martiny, J. B. H., & Field, D. (2005) · Ecology Letters · doi:10.1111/j.1461-0248.2005.00837.x · Cited by 33
Characterization of alternatively spliced isoforms of the type I interleukin-1 receptor on iNOS induction in rat hepatocytes
Yamada, M., Nishizawa, M., Nakatake, R., Habara, K., Yoshida, H., Ozaki, T., Matsui, K., Hamada, Y., Kamiyama, Y., Ito, S., et al. (2007) · Nitric Oxide · doi:10.1016/j.niox.2007.06.003 · Cited by 33
Molecular cloning and characterization of genes encoding BURP domain-containing protein in the mangrove, Bruguiera gymnorrhiza
Banzai, T., Sumiya, K., Hanagata, N., et al. (2001) · Trees · doi:10.1007/s00468-001-0144-4 · Cited by 33
“The PSORT program ( Nakai and Horton 1999 ) predicted that the first 20 amino acid residues in the N-terminal of the BgBDC3 protein could be cleaved off, and that the mature protein would be located outside the cell.”
Background
An analysis of amino acid sequences surrounding archaeal glycoprotein sequons
Abu‐Qarn, M., & Eichler, J. (2006) · Archaea · doi:10.1155/2006/510578 · Cited by 33
Differential gene expression between squamous cell carcinoma of esophageus and its normal epithelium; altered pattern of mal, akr1c2, and rab11a expression
Noureini, S. K. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i12.1716 · Cited by 34
Augur—a computational pipeline for whole genome microbial surface protein prediction and classification
Billion, A., Ghai, R., Chakraborty, T., et al. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl466 · Cited by 33
“Our predictions are slightly more conservative than those provided by PSORT ( Nakai and Horton, 1999 ) used by the authors for lipoproteins and LPXTG motif prediction.”
Method
Two MAR DNA‐binding proteins of the pea nuclear matrix identify a new class of DNA‐binding proteins
Hatton, D., & Gray, J. C. (1999) · The Plant Journal · doi:10.1046/j.1365-313x.1999.00468.x · Cited by 33
A Circadian Neuropeptide, Pigment-Dispersing Factor–PDF, in the Last-Summer Cicada Meimuna opalifera: cDNA Cloning and Immunocytochemistry
Sato, S., Chuman, Y., Matsushima, A., et al. (2002) · ZOOLOGICAL SCIENCE · doi:10.2108/zsj.19.821 · Cited by 33
“Nuclear localization was also predicted by means of the network computer-assisted system running the PSORT II program (Nakai and Kanehisa, 1992; Reinhardt and Hubbard, 1998; Nakai and Horton 1999).”
Method
Plant membrane proteome databases
Schwacke, R., Flügge, U., & Kunze, R. (2004) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2004.09.011 · Cited by 33
Isolation and Identification of Glycosylphosphatidylinositol-Anchored Arabinogalactan Proteins and Novel β-Glucosyl Yariv-Reactive Proteins from Seeds of Rice (Oryza sativa)
Mashiguchi, K., Yamaguchi, I., & Suzuki, Y. (2004) · Plant and Cell Physiology · doi:10.1093/pcp/pch208 · Cited by 33
Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6
Dugan, G. E., & Hewitt, E. W. (2008) · Journal of Virology · doi:10.1128/jvi.01705-07 · Cited by 33
“The transmembrane domains and signal sequences were predicted with PSORT II (32); the predicted signal sequences for both proteins are shown in italic type.”
Method
α-Latrotoxin: from structure to some functions
Ushkaryov, Y. A. (2002) · Toxicon · doi:10.1016/s0041-0101(01)00204-5 · Cited by 33
Protein Import: the Hitchhikers Guide into Chloroplasts
Vothknecht, U., & Soll, J. (2000) · Biological chemistry · doi:10.1515/bc.2000.110 · Cited by 38
“The deduced amino acid sequence including transit sequences where further analysed with the programs PSORT (Nakai and Horton, 1999), ChloroP (Emanuelsson et al., 1999) and SignalP (Nielsen et al., 1997) to see whether they would correctly predict the chloroplast location and presequence cleavage.”
Method
Characterization of the Nuclear Localization and Nuclear Export Signals of Bovine Herpesvirus 1 VP22
Zheng, C., Brownlie, R. M., Babiuk, L. A., et al. (2005) · Journal of Virology · doi:10.1128/jvi.79.18.11864-11872.2005 · Cited by 33
“However, a putative NLS, (295)RPRR(298), exists in the C terminus of HSV-1 VP22, as predicted by PSORT II (23).”
Background
Transcriptional Expression Characteristics and Subcellular Localization of ADP-Glucose Pyrophosphorylase in the Oil Plant Perilla frutescens
Choi, S., Kim, K.-H., Kavaklı, İ. H., et al. (2001) · Plant and Cell Physiology · doi:10.1093/pcp/pce019 · Cited by 33
Locating apoptosis proteins by incorporating the signal peptide cleavage sites into the general form of Chou's Pseudo amino acid composition
Qin, Y., Zheng, L., & Huang, J. (2013) · International Journal of Quantum Chemistry · doi:10.1002/qua.24383 · Cited by 32
Sc65 Is a Novel Endoplasmic Reticulum Protein That Regulates Bone Mass Homeostasis
Gruenwald, K., Castagnola, P., Besio, R., Dimori, M., Chen, Y., Akel, N. S., Swain, F. L., Skinner, R. A., Eyre, D. R., Gaddy, D., et al. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2075 · Cited by 32
“1, Phobius, Philius) or protein subcellular localization prediction (Psort II, TargetP)((31,32)) was performed.”
Alternative Expression of Vacuolar Iron Transporter and Ferritin Genes Leads to Blue/Purple Coloration of Flowers in Tulip cv. ‘Murasakizuisho’
Shoji, K., Momonoi, K., & Tsuji, T. (2009) · Plant and Cell Physiology · doi:10.1093/pcp/pcp181 · Cited by 32
Predicting Nuclear Localization
Hawkins, J., Davis, L., & Mikael Bodén, A. (2007) · Journal of Proteome Research · doi:10.1021/pr060564n · Cited by 32

Authors: Nakai, K., & Horton, P.
Affiliations: The University of Osaka (JP)
Corresponding author: Nakai, Kenta
ORCID: Nakai, Kenta
Horton, Paul
Venue: Trends in Biochemical Sciences
Publisher: Elsevier BV
Published: 1999-01
Volume: 24
Issue: 1
Pages: 34-35
ISSN: 0968-0004 (ISSN-L)
DOI: 10.1016/s0968-0004(98)01336-x
OpenAlex: W2006211612
Cited by: 2,181
References: 13
Citations by year: 2026: 25 · 2025: 26 · 2024: 43 · 2023: 33 · 2022: 23 · 2021: 31 · 2020: 36 · 2019: 53 · 2018: 59 · 2017: 46 · 2016: 59 · 2015: 69 · 2014: 76 · 2013: 89 · 2012: 105
FWCI: 27.84
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Trends in Biochemical Sciences (publishedVersion)
PubMed (publishedVersion)
Funders: Ministry of Education, Culture, Sports, Science and Technology
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Machine Learning in Bioinformatics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Keywords: protein sorting signals, subcellular localization prediction, protein localization, signal peptide, amino acid composition, protein function prediction
MeSH terms: Algorithms, Proteins, Software, Subcellular Fractions, Protein Sorting Signals

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PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

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