The DOI matches its Crossref record; 21 of the 23 references it cites were found in a registry or an index.
Ultraviolet radiation and skin cancer of humans
Abstract
Current scientific evidence indicates that stratospheric ozone has declined worldwide over the past 20 years. The trend estimates are markedly dependent on the geographical location and are highly seasonal. Winter trends are much more negative than those for summer and autumn. Projections based on current assumptions of chlorine release suggest that this decline will continue into the next century. On the basis of the decrease in ozone over the mid-latitudes, an increase in biologically effective ultraviolet radiation (UVR) of 4%-9% is expected, depending on the season and geographical location. However, the UVR penetration to the Earth's surface is greatly affected by clouds, aerosols and tropospheric ozone, and current increases, if any, have not been as large as this. Direct evidence for the induction of non-melanoma skin cancer (NMSC) due to UVR has been derived from animal experiments in mice and rats. Numerous epidemiological data confirm that this relationship also holds for human skin. The increase in NMSC incidence in the past two decades is not likely to be due to the decrease in ozone, given the long latency (two to three decades) associated with UVR effects on skin. A knowledge of the action spectrum for NMSC development suggests that a 1% depletion in stratospheric ozone may be expected to increase NMSC, at equilibrium, by about 2.0% The evidence on the role of UVR exposure in the development of malignant melanoma (MM) is less certain. It has been estimated that a 1% reduction in ozone may cause an increase in MM of 0.6%.
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“The incidence of infectious skin disease has been shifting due to climate conditions that favor the transmission of microbes, and global skin cancer risk is rising due to ozone layer depletion [98,99,100,101].”
From The Environmental Determinants of Skin Health: Linking Climate Change, Air Pollution, and the Dermatologic Disease Burden (2025) · cites this paper as [98]
Citations
Cites
A role for sunlight in skin-cancer – UV-induced p53 mutations in squamous-cell carcinoma
Brash, D. E., Rudolph, J. A., Simon, J. A., Lin, A., McKenna, G. J., Baden, H. P., Halperin, A. J., & Pontén, J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.22.10124 · Cited by 1,959
The Emerging Epidemic of Melanoma and Squamous Cell Skin Cancer
Glass, A. G. (1989) · JAMA · doi:10.1001/jama.1989.03430150065027 · Cited by 474
Human exposure to ultraviolet radiation. Risks and regulations
Passchier, W. F., & Bosnjakovic, B. F. M. (1987) · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) · Cited by 409
The relationship between erythemal UV and ozone, derived from spectral irradiance measurements
McKenzie, R., Matthews, W. A., & Johnston, P. V. (1991) · Geophysical Research Letters · doi:10.1029/91gl02786 · Cited by 186
Madronich, S., & de Gruijl, F. R. (1993) · Nature · doi:10.1038/366023a0 · Cited by 179
Skin Cancer in Blacks in the United States
Halder, R. M., & Bang, K. M. (1988) · Dermatologic Clinics · doi:10.1016/s0733-8635(18)30651-x · Cited by 161
Incidence of Nonmelanoma Skin Cancer
Urbach, F. (1991) · Dermatologic Clinics · doi:10.1016/s0733-8635(18)30379-6 · Cited by 143
Self-citationIndications of future decreasing trends in skin‐melanoma mortality among whites in the United States
Scotto, J., Pitcher, H., & Lee, J. A. H. (1991) · International Journal of Cancer · doi:10.1002/ijc.2910490403 · Cited by 105
Madronich, S., & de Gruijl, F. R. (1994) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1994.tb02980.x · Cited by 83
Trends in column ozone based on TOMS data: Dependence on month, latitude, and longitude
Niu, X., Frederick, J. E., Stein, M. L., & Tiao, G. C. (1992) · Journal of Geophysical Research Atmospheres · doi:10.1029/92jd01392 · Cited by 72
Research works printed but not linked: 3
- Urbach, 1995, Biologic effects of increased ultraviolet radiation: plankton, plants and people, Vol. 1, 88
- de Gruijl, 1995, The wavelength dependence of ultraviolet carcinogenesis in humans and its relation to risk assessment of stratospheric ozone depletion, Health Physics, 67, 317
- Streilein, 1993, Immunology of human skin and its relationship to skin cancer, Cancer Bull., 45, 225
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Hellweg, C. E., & Baumstark‐Khan, C. (2007) · Radiation and Environmental Biophysics · doi:10.1007/s00411-007-0104-5 · Cited by 6
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Huang, Y., Zhou, S., Liu, H., Zhou, X., Yuan, M., Hou, F., Chen, S., Chen, J., Wang, L., & Jiang, W. (2023) · Briefings in Bioinformatics · doi:10.1093/bib/bbad066 · Cited by 5
Mutti, A. E. C. (2014) · Revista Baiana Saúde Pública · doi:10.22278/2318-2660.2004.v28.n2.a1195 · Cited by 5
Dorr, M. M., Guignard, R., Auger, F. A., & Rochette, P. J. (2020) · British Journal of Dermatology · doi:10.1111/bjd.19117 · Cited by 4
Chen, L., Shen, Z., & Wu, J. (2011) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2011.00616.x · Cited by 4
Salinas, H., Almenara, J., Reyes, A. P., Silva, P. C., Marcia Erazo, B., & Abellán, M. J. (2006) · Actas Dermo-Sifiliográficas · doi:10.1016/s0001-7310(06)73391-9 · Cited by 4
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Klop, W. M. C., Elshot, Y. S., Beck, A. C. C., Brandsen, R., & Lohuis, P. J. F. M. (2019) · Facial Plastic Surgery · doi:10.1055/s-0039-1695044 · Cited by 4
Basher, A. A., Ibrahim, N. A., Liu, H.-Y., Basher, N. S., Essa, M. O. A., Husien, H. M., Adam, S. Y., & Cai, D. (2026) · Antioxidants · doi:10.3390/antiox15050575 · Cited by 3
Bhattarai, B. K., Kjeldstad, B., & Thorseth, T. M. (2011) · Advances in Atmospheric Sciences · doi:10.1007/s00376-010-9222-0 · Cited by 3
Stimpfle, D. W., Serra, A. L., Wuthrich, R. P., French, L. E., Braun, R. P., & Hofbauer, G. F. L. (2014) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12771 · Cited by 3
Reduced ultraviolet irradiation delays subsequent squamous cell carcinomas in hairless mice
Togsverd‐Bo, K., Lerche, C. M., Poulsen, T., Hædersdal, M., & Wulf, H. C. (2009) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2009.00470.x · Cited by 3
Melanoma Techniques and Protocols
Nickoloff, B. J. (2001) · Humana Press eBooks · doi:10.1385/1592591450 · Cited by 3
Speer, R. M., Yu, H., Zhou, X., Nandi, S. P., Alexandrov, L. B., Guo, Y. P., Hudson, L. G., & Liu, K. J. (2023) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2023.116773 · Cited by 2
Ehsani, S., Croul, S. E., Knight, K., & Kiehl, T. (2009) · Nature Precedings · doi:10.1038/npre.2009.2969.1 · Cited by 2
Leow, L. J., & Zubrzycki, N. (2023) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.15620 · Cited by 1
Total Column Ozone over Kathmandu using OMI Satellite
Bhattarai, B. K. (1970) · Journal of the Institute of Engineering · doi:10.3126/jie.v8i1-2.5123 · Cited by 1
Analysis of Ozone (O3) and Erythemal UV (EUV) measured by TOMS in the equatorial African belt
Ssenyonga, T., Stamnes, J. J., Dahlback, A., Steigen, A. L., Okullo, W., & Frette, Ø. (2010) · South African Journal of Science · doi:10.4102/sajs.v106i1/2.12 · Cited by 1
Reconstruction in the Elderly Patient
Ross, A., & Wang, T. (2006) · CRC Press eBooks · doi:10.3109/9780849374487-52 · Cited by 1
Comparison of the biologically effective UV in the shade for three action spectra
Turnbull, D., & Parisi, A. V. (2005) · University of Southern Queensland ePrints (University of Southern Queensland) · Cited by 1
Cellular and genomic toxicity produced by UV light in Chinese hamster ovary cells
Rahman, I. (2014) · Pakistan Journal of Pharmaceutical Sciences · doi:10.36721/pjps/27/2/2014/2141/295-301 · Cited by 1
Seasonal Variation in the Diagnosis of Retinoblastoma
Singh, S., Nishath, T., Fabian, I. D., Li, X., Othus, M. K. D., Tzukikawa, M., & Stacey, A. W. (2022) · Ophthalmic Epidemiology · doi:10.1080/09286586.2022.2153872 · Cited by 1
Dissection of Immunosuppressive Effects of Ultraviolet Radiation
Ullrich, S. E., & Schmitt, D. A. (2003) · Humana Press eBooks · doi:10.1385/1-59259-145-0:85 · Cited by 1
Fluorescência óptica no diagnóstico de lesões teciduais
Coelho, V. H. M. (2005) · doi:10.11606/d.82.2005.tde-30072007-171059
The Interactive Toxicity of Benzo(a)Pyrene and Ultraviolet Radiation - an In Vitro Investigation
Lyle, Z. J. (2008) · PEARL (University of Plymouth) · doi:10.24382/2643
Lesiones pigmentadas en la pirámide nasal
Sánchez, M. C. M., & Ruíz‐Villaverde, R. (2003) · Piel · doi:10.1016/s0213-9251(03)72666-5
Ultraviolet Radiation and Squamous Cell Carcinoma in Human Skin
Wassberg, C. (2001) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Sun Protection in New Zealand Teacher-led Early Childhood Centres
Duignan, M. (2011)
Westin, A. T. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2016.tde-03092014-230644
da Rosa, M. B., Schuch, N. J., Rampelotto, P. H., Schuch, A. P., Pinheiro, D. K., & Munakata, N. (2007) · International Congress of the Brazilian Geophysical Society · doi:10.3997/2214-4609-pdb.172.sbgf0036_07
Blasco-Brusola, A. (2021) · RiuNet (Universitat Politècnica de València) · doi:10.4995/thesis/10251/165256
The Role of Ionizing Radiation in the Etiology of Cancer
Uzal, C., & Çaloğlu, M. (2002) · DergiPark (Istanbul University)
da Rosa, M. B., Schuch, N. J., Rampelotto, P. H., Schuch, A. P., Pinheiro, D. K., & Munakata, N. (2007) · doi:10.1190/sbgf2007-046
Skin cancer risk in hereditary mixed cancer syndromes
Nikkola, V., Alakoski, A., Mecklin, J., Seppälä, T. T., Nikkola, J., & Schrader, K. A. (2025) · Hereditary Cancer in Clinical Practice · doi:10.1186/s13053-025-00326-7
Metadata
- Authors
- Urbach, F.
- Corresponding author
- Urbach, Frederick
- Venue
- Journal of Photochemistry and Photobiology B: Biology
- Publisher
- Elsevier BV
- Published
- 1997-08
- Volume
- 40
- Issue
- 1
- Pages
- 3-7
- ISSN
- 1011-1344 (ISSN-L)
- OpenAlex
- W2080752514
- Cited by
- 136
- References
- 23
- Citations by year
- 2026: 1 · 2025: 3 · 2023: 5 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 1 · 2017: 6 · 2016: 5 · 2014: 10 · 2013: 2 · 2012: 3
- FWCI
- 8.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Photochemistry and Photobiology B Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Dermatology › Nonmelanoma Skin Cancer Studies
- Physical Sciences › Earth and Planetary Sciences › Atmospheric Science › Atmospheric Ozone and Climate
- Keywords
- ultraviolet radiation, skin cancer, stratospheric ozone depletion, non-melanoma skin cancer, melanoma, chlorine release, tropospheric ozone, action spectrum
- MeSH terms
- Animals, Forecasting, Humans, Melanoma, Neoplasms, Radiation-Induced, Ozone, Seasons, Skin Neoplasms, Sunlight, Ultraviolet Rays, Incidence, Mice, Rats
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