Cited by 83Drug-Induced Adverse ReactionsFood Allergy and Anaphylaxis ResearchContact Dermatitis and Allergies

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Skin testing and oral penicillin challenge in patients with a history of remote penicillin allergy.

Goldberg, Arnon, Confino-Cohen, Ronit·2008·Annals of Allergy, Asthma & Immunology

Open this paper in CoChat — free account

Abstract

Background Penicillin administration is usually contraindicated in penicillin-allergic patients with positive skin test results.Objective To examine whether penicillin oral challenge for patients with a history of remote non-life-threatening allergic reaction to penicillin can be well tolerated irrespective of skin test results.Methods In a prospective open-label trial, 8,702 individuals were screened between November 1998 and January 2000. Of 687 patients with a non-life-threatening allergic reaction to penicillin, occurring longer than 3 years earlier, 169 were enrolled. Regardless of the response to penicillin skin testing, patients received the usual 1-day dosage of penicillin and amoxicillin, on 2 separate occasions. Two to 6 years later, a follow-up was conducted to assess the outcomes of further penicillin administration.Results A total of 272 combined skin tests and oral challenges were performed on 169 patients. Among 137 challenges with a positive skin test result and 135 patients with a negative skin test result, 9 (6.6%) and 5 (3.7%) (P = .29), respectively, developed a mild rash to oral challenge. At follow-up, 2 to 6 years afterward, 3 of 55 patients (5.5%) who were given a full treatment course of penicillin developed a mild skin eruption.Conclusions Positive penicillin skin test results for patients with a remote history of non-life-threatening allergic reaction to penicillin were not associated with a greater prevalence of adverse reactions to oral challenge with penicillin than negative results. Because skin testing is considered the gold standard and the safest method for predicting tolerance to penicillin administration, oral penicillin challenge may be used as a diagnostic method only in these specific patients when skin testing is not feasible.

Integrity signals

Registry

Crossref · 10.1016/s1081-1206(10)60402-4

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A Controlled Trial of Immunotherapy in Insect Hypersensitivity
Hunt, K. J., Valentine, M. D., Sobotka, A. K., Benton, A. W., Amodio, F. J., & Lichtenstein, L. M. (1978) · New England Journal of Medicine · doi:10.1056/nejm197807272990401 · Cited by 708
Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock.
Idsøe, O., GUTHE, T., Willcox, R. R., & WECK, A. L. D. (1968) · PubMed Central · Cited by 539
Immediate Hypersensitivity Reactions to Beta-Lactam Antibiotics
Saxon, A., BEALL, G. N., ROHR, A. S., & Adelman, D. C. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-2-204 · Cited by 410
Clinical experience with penicillin skin testing in a large inner-city STD clinic.
Gadde, J. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03510200062033 · Cited by 344
Immediate hypersensitivity reactions to penicillin and related antibiotics
Weiss, M., & Adkinson, N. F. (1988) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1988.tb02904.x · Cited by 340
Results of the National Institute of Allergy and Infectious Diseases Collaborative Clinical Trial to test the predictive value of skin testing with major and minor penicillin derivatives in hospitalized adults.
Sogn, D. D. (1992) · Archives of Internal Medicine · doi:10.1001/archinte.1992.00400170105020 · Cited by 337
Skin testing to detect penicillin allergy
Sullivan, T. J., Wedner, H. J., Shatz, G. S., Yecies, L. D., & Parker, C. W. (1981) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(81)90180-9 · Cited by 326
Natural evolution of skin test sensitivity in patients allergic to β-lactam antibiotics
Blanca, M., Torres, M. J., García, J. J., Romano, A. G., Mayorga, C., de Ramon, E., Vega, J. M. G., Miranda, A., & Juárez, C. (1999) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(99)70439-2 · Cited by 317
Cow's milk protein allergy and intolerance in infancy Some clinical, epidemiological and immunological aspects
Høst, A. (1994) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.1994.tb00352.x · Cited by 317
Drug Provocation Tests in Patients with a History Suggesting an Immediate Drug Hypersensitivity Reaction
Messaad, D., Sahla, H., Benahmed, S., Godard, P., Bousquet, J., & Demoly, P. M. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-140-12-200406150-00009 · Cited by 298

Show all 35 references

Sorted by citations

Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 3,018
Drug Allergy: An Updated Practice Parameter
(2010) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2010.08.002 · Cited by 982
International Con sensus on drug allergy
Demoly, P. M., Adkinson, N. F., Brockow, K., Castells, M., Chiriac, A. M., Greenberger, P. A., Khan, D. A., Lang, D. M., Park, H., Pichler, W. J., et al. (2014) · Allergy · doi:10.1111/all.12350 · Cited by 932
Update on the evaluation of hypersensitivity reactions to betalactams
Blanca, M., Romano, A. G., Torres, M. J., Fernández, J., Mayorga, C., Rodriguez, J., Demoly, P. M., Bousquet, P., Merk, H. F., Sanz, M. L., et al. (2009) · Allergy · doi:10.1111/j.1398-9995.2008.01924.x · Cited by 450
The role of penicillin in benign skin rashes in childhood: A prospective study based on drug rechallenge
Caubet, J., Kaiser, L., Lemaître, B., Fellay, B., Gervaix, A., & Eigenmann, P. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.08.025 · Cited by 343
The challenge of de‐labeling penicillin allergy
Stone, C. A., Trubiano, J. A., Coleman, D. T., Rukasin, C. R. F., & Phillips, E. J. (2019) · Allergy · doi:10.1111/all.13848 · Cited by 270
Safety and outcomes of oral graded challenges to amoxicillin without prior skin testing.
Iammatteo, M., Alvarez Arango, S., Ferastraoaru, D., Akbar, N., Lee, A. Y., Cohen, H. W., & Jerschow, E. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2018.05.008 · Cited by 157
Allergy Testing in Children With Low-Risk Penicillin Allergy Symptoms
Vyles, D. E., Adams, J., Chiu, A. M., Simpson, P. M., Nimmer, M., & Brousseau, D. C. (2017) · PEDIATRICS · doi:10.1542/peds.2017-0471 · Cited by 141
Accuracy of penicillin allergy diagnostic tests: A systematic review and meta-analysis
Sousa‐Pinto, B., Tarrio, I., Blumenthal, K. G., Araújo, L. M., Azevedo, L. F., Delgado, L., & Fonseca, J. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.04.058 · Cited by 123
The Falling Rate of Positive Penicillin Skin Tests from 1995 to 2007
Macy, E. M., Schatz, M. N., Lin, C., & Poon, K. T. (2009) · The Permanente Journal · doi:10.7812/tpp/08-073 · Cited by 115
Antibiotic Allergies in Children and Adults: From Clinical Symptoms to Skin Testing Diagnosis
Romano, A. G., & Caubet, J. (2014) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2013.11.006 · Cited by 106
Diagnosis of penicillin allergy revisited: the value of case history, skin testing, specific IgE and prolonged challenge
Hjortlund, J., Mortz, C. G., Skov, P. S., & Bindslev‐Jensen, C. (2013) · Allergy · doi:10.1111/all.12195 · Cited by 101
Amoxicillin Allergy in Children: Five-Day Drug Provocation Test in the Diagnosis of Nonimmediate Reactions
Mori, F., Cianferoni, A., Barni, S., Pucci, N., Rossi, M. E., & Novembre, E. M. (2015) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2014.11.001 · Cited by 98
Evaluating Penicillin Allergies Without Skin Testing
Banks, T. A., Tucker, M. H., & Macy, E. M. (2019) · Current Allergy and Asthma Reports · doi:10.1007/s11882-019-0854-6 · Cited by 91
Prospective assessment of diagnostic tests for pediatric penicillin allergy
Ibáñez, M. D., del Río, P. R., Lasa, E. M., Joral, A., Ruiz‐Hornillos, J., Muñoz, C., Gómez‐Traseira, C., Escudero, C., Rivera, J. M., Garriga‐Baraut, T., et al. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.05.013 · Cited by 86
Penicillin skin testing in the evaluation and management of penicillin allergy
Fox, S., & Park, M. A. (2010) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2010.05.010 · Cited by 82
Penicillin Skin Testing: Potential Implications for Antimicrobial Stewardship
Unger, N. R., Gauthier, T. P., & Cheung, L. (2013) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1288 · Cited by 79
Penicillin allergy de-labelling ahead of elective surgery: feasibility and barriers
Savic, L. C., Gurr, L., Kaura, V., Toolan, J., Sandoe, J. A. T., Hopkins, P. M., & Savic, S. (2018) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.09.009 · Cited by 71
Multicenter Australian Study to Determine Criteria for Low- and High-Risk Penicillin Testing in Outpatients
Stevenson, B. R., Trevenen, M., Klinken, E., Smith, W., Yuson, C., Katelaris, C. H., Perram, F., Burton, P. K., Yun, J. J., Cai, F., et al. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.09.025 · Cited by 63
Beta lactam allergy and resensitization in children with suspected beta lactam allergy
Hershkovich, J., Broides, A., Kirjner, L., Smith, H., & Gorodischer, R. (2009) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2008.03180.x · Cited by 60
A Closer Look at Penicillin Allergy History: Systematic Review and Meta-Analysis of Tolerance to Drug Challenge
DesBiens, M. T., Scalia, P., Ravikumar, S., Glick, A. L., Newton, H., Erinne, O., & Riblet, N. B. V. (2019) · The American Journal of Medicine · doi:10.1016/j.amjmed.2019.09.017 · Cited by 57
Penicillin Skin Testing Is a Safe and Effective Tool for Evaluating Penicillin Allergy in the Pediatric Population
Fox, S. J., & Park, M. A. (2014) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2014.04.013 · Cited by 53
Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations
Savic, L. C., Khan, D. A., Kopač, P., Clarke, R. C., Cooke, P., Dewachter, P., Ebo, D. G., Garcez, T. P., Garvey, L., Guttormsen, A. B., et al. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2019.01.026 · Cited by 54
The Importance of Prolonged Provocation in Drug Allergy — Results From a Danish Allergy Clinic
Fransson, S., Mosbech, H., Kappel, M., Hjortlund, J., Poulsen, L. K., Kvisselgaard, A. D., & Garvey, L. H. (2017) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2017.02.024 · Cited by 45
Short protocol for the study of paediatric patients with suspected betalactam antibiotic hypersensitivity and low risk criteria
Moral, L., Garde, J. G., Toral, T., Fuentes, M. J., & Marco, N. (2011) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2010.10.002 · Cited by 44
Performance in real life of the European Network on Drug Allergy algorithm in immediate reactions to beta‐lactam antibiotics
Moreno, E., Laffond, E., Muñoz‐Bellido, F. J., Gracia, M. T., Macías, E., Moreno, A., & Davila, I. J. (2016) · Allergy · doi:10.1111/all.13032 · Cited by 42
Direct Challenges for the Evaluation of Beta-Lactam Allergy: Evidence and Conditions for Not Performing Skin Testing
Iammatteo, M., Lezmi, G., Confino‐Cohen, R., Tucker, M. H., Ben‐Shoshan, M., & Caubet, J. (2021) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2021.04.073 · Cited by 40
Frequency of severe reactions following penicillin drug provocation tests: A Bayesian meta‐analysis
Cardoso‐Fernandes, A., Blumenthal, K. G., Chiriac, A. M., Tarrio, I., João, D., Delgado, L., Fonseca, J., Azevedo, L. F., & Sousa‐Pinto, B. (2021) · Clinical and Translational Allergy · doi:10.1002/clt2.12008 · Cited by 39
Positive Skin Test or Specific IgE to Penicillin Does Not Reliably Predict Penicillin Allergy
Tannert, L. K., Mortz, C. G., Skov, P. S., & Bindslev‐Jensen, C. (2017) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2017.03.014 · Cited by 39
Pro and Contra: Provocation Tests in Drug Hypersensitivity
Soyer, Ö., Şahiner, Ü. M., & Şekerel, B. E. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18071437 · Cited by 38
Drug provocation tests in hypersensitivity drug reactions
Rerkpattanapipat, T., Chiriac, A. M., & Demoly, P. M. (2011) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e328348a4e9 · Cited by 36
Antibiotic Allergy
Romano, A. G., & Warrington, R. (2014) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2014.03.003 · Cited by 35
Full-Course Drug Challenge Test in the Diagnosis of Delayed Allergic Reactions to Penicillin
Borch, J. E., & Bindslev‐Jensen, C. (2011) · International Archives of Allergy and Immunology · doi:10.1159/000320384 · Cited by 35
Negative predictive value of drug provocation tests in children
Mısırlıoğlu, E. D., Toyran, M., Çapanoğlu, M., Kaya, A., Civelek, E., & Kocabaş, C. N. (2014) · Pediatric Allergy and Immunology · doi:10.1111/pai.12286 · Cited by 34
Determining the impact of Benzathine penicillin G prophylaxis in children with latent rheumatic heart disease (GOAL trial): Study protocol for a randomized controlled trial
Beaton, A., Okello, E., Engelman, D., Grobler, A. C., Scheel, A. M., DeWyer, A., Sarnacki, R., Omara, I. O., Rwebembera, J., Sable, C., et al. (2019) · American Heart Journal · doi:10.1016/j.ahj.2019.06.001 · Cited by 34
Resensitization in suspected penicillin allergy
Doña, I., Guidolin, L., Bogas, G., Olivieri, E., Labella, M., Schiappoli, M., María, R. S. D. S., Dama, A., Salas, M. L., Senna, G., et al. (2022) · Allergy · doi:10.1111/all.15508 · Cited by 31
Penicillin minor determinants
Adkinson, N. F., Mendelson, L. M., Ressler, C., & Keogh, J. C. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.09.459 · Cited by 30
Drug Reactions
BREATHNACH, S. M. (2010) · Wiley eBooks · doi:10.1002/9781444317633.ch75 · Cited by 31
Drug re-challenges in cutaneous adverse drug reactions: information and effectiveness in the long-term management of patients
Waton, J., Pouget-Jasson, C., Ayav, C., Tréchot, P., Bursztejn, A. ‐., Schmutz, J. ‐., & Barbaud, A. M. (2011) · Allergy · doi:10.1111/j.1398-9995.2011.02554.x · Cited by 27
Prospective, multicenter clinical trial to validate new products for skin tests in the diagnosis of allergy to penicillin.
Fernández, J., Torres, M. J., Campos, J., Arribas-Poves, F., & Blanca, M. (2013) · PubMed · Cited by 26
Skin testing only with penicillin G in children with a history of penicillin allergy
Picard, M., Paradis, L. P., Bégin, P., Paradis, J., & Roches, A. D. (2014) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2014.04.017 · Cited by 24
Drug provocation testing: risk stratification is key
Garvey, L. H., & Savic, L. C. (2019) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000543 · Cited by 23
Impact of an antimicrobial stewardship initiative to evaluate β-lactam allergy in patients ordered aztreonam
Estep, P. M., Ferreira, J., Dupree, L. H., Aldridge, P. J., & Jankowski, C. A. (2016) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp150440 · Cited by 22
Managing possible antibiotic allergy in children
Caubet, J., & Eigenmann, P. (2012) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e3283523f8b · Cited by 22
Cephalosporin allergy label is misleading
Yuson, C., Katelaris, C. H., & Smith, W. (2018) · Australian Prescriber · doi:10.18773/austprescr.2018.008 · Cited by 21
Usefulness of drug provocation tests in children with a history of adverse drug reaction
Na, H. R., Lee, J. M., Jung, J. W., & Lee, S. (2011) · Korean Journal of Pediatrics · doi:10.3345/kjp.2011.54.7.304 · Cited by 20
To challenge or not to challenge: Literature data on the positive predictive value of skin tests to beta-lactams
Chiriac, A. M., Vasconcelos, M. J., Izquierdo, L., Ferrando, L., Nahas, O., & Demoly, P. M. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.01.060 · Cited by 19
Role of clinical history in beta-lactam hypersensitivity
Plager, J. H., Judd, A. D., & Blumenthal, K. G. (2021) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000758 · Cited by 19
Safety of Direct Drug Provocation for the Evaluation of Penicillin Allergy in Low-Risk Adults
Brillant-Marquis, F., Proulx, É., Ratnarajah, K., Lavoie, A., Gauthier, A., Gagnon, R., Boursiquot, J.-N., Verreault, N., Marois, L., Bédard, M.-A., et al. (2023) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2023.10.035 · Cited by 16
Is a positive intracutaneous test induced by penicillin mediated by histamine? A cutaneous microdialysis study in penicillin-allergic patients
Tannert, L. K., Falkencrone, S., Mortz, C. G., Bindslev‐Jensen, C., & Skov, P. S. (2017) · Clinical and Translational Allergy · doi:10.1186/s13601-017-0179-2 · Cited by 15
Prospective Assessment of Penicillin Allergy (PAPA): Evaluating the performance of penicillin allergy testing and post-delabelling outcomes among Hong Kong Chinese
Li, T. S., Hui, H. K. S., Kan, A. K. C., Yeung, M. H. Y., Wong, J. C. Y., Chiang, V., & Li, P. H. (2023) · Asian Pacific Journal of Allergy and Immunology · doi:10.12932/ap-270922-1469 · Cited by 15
Narrative review of recent developments and the future of penicillin allergy de-labelling by non-allergists
Powell, N., Blank, M., Luintel, A., Elkhalifa, S., Bhogal, R., Wilcock, M., Wakefield, M., & Sandoe, J. A. T. (2024) · npj Antimicrobials and Resistance · doi:10.1038/s44259-024-00035-6 · Cited by 12
Varying penicillin allergy testing practices in the United States: A time for consensus
Gerace, K. S., Karlin, E. M., McKinnon, E., & Phillips, E. J. (2015) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2015.03.010 · Cited by 12
Challenge Test Results in Patients With Suspected Penicillin Allergy, but No Specific IgE
Holm, A., & Mosbech, H. (2011) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2011.3.2.118 · Cited by 12
Additional provocation testing in patients with negative provocation test results with β-lactam antibiotics
Çapanoğlu, M., Vezir, E., Mısırlıoğlu, E. D., Güvenir, H., Büyüktiryaki, B., Toyran, M., & Kocabaş, C. N. (2015) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2015.10.010 · Cited by 12
Improving Antibiotic Stewardship for Inpatients with Reported Beta-Lactam Allergies and Limited Access to Penicillin Skin Testing
Berger, R. E., Singh, H. K., Loo, A. S., Cooley, V., Osorio, S. N., Lee, J. I., & Simon, M. S. (2021) · The Joint Commission Journal on Quality and Patient Safety · doi:10.1016/j.jcjq.2021.12.001 · Cited by 11
Penicillin skin testing in the management of penicillin allergy in an outpatient pediatric population
Anterasian, C., & Geng, B. (2018) · Allergy and Asthma Proceedings · doi:10.2500/aap.2018.39.4138 · Cited by 10
Suspected Reaction with Cephalosporin May Be a Predictive Factor for β-Lactam Allergy in Children
Simsek, I. E., Çöğürlü, M. T., & Aydoğan, M. (2018) · International Archives of Allergy and Immunology · doi:10.1159/000494506 · Cited by 9
Intramuscular versus enteral penicillin prophylaxis to prevent progression of rheumatic heart disease: Study protocol for a noninferiority randomized trial (the GOALIE trial)
Rwebembera, J., Ndagire, E., Carvalho, N., Webel, A. R., Sable, C., Okello, E., Sarnacki, R., Spaziani, A. M., Atukunda, M., Engelman, D., et al. (2024) · American Heart Journal · doi:10.1016/j.ahj.2024.05.012 · Cited by 7
Diagnosis and selection of alternative antibiotics in beta-lactams hypersensitivity reactions: Current recommendations and challenges
Kanannejad, Z., Pourvali, A., Esmaeilzadeh, H., Shoormasti, R. S., Fazlollahi, M. R., Fallahpour, M., & Zaremehrjardi, F. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110573 · Cited by 7
Description of the combined evidence-based, theory-based and person-based approaches used to develop a behavioural intervention package to support non-allergist healthcare workers to remove incorrect penicillin allergy records from medical and surgical adult inpatients in a UK hospital
Powell, N., Upton, M., Kent, B., Sandoe, J. A. T., & Tonkin-Crine, S. K. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-096452 · Cited by 7
Placebo, Nocebo, and Patient-Reported Outcome Measures in Drug Allergy
Bavbek, S., Özyiğit, L. P., Baiardini, I., Braido, F., Gigia Roizen, G., & Jerschow, E. (2022) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2022.11.033 · Cited by 7
Analysis of a beta-lactam allergy assessment protocol challenging diverse reported allergies managed by an antimicrobial stewardship program
Jacobs, M. W., Bremmer, D. N., Shively, N. R., Moffa, M. A., Trienski, T. L., Carr, D. R., Buchanan, C., & Walsh, T. (2023) · Antimicrobial Stewardship & Healthcare Epidemiology · doi:10.1017/ash.2023.432 · Cited by 7
Challenging dogmas: Intravenous versus oral beta-lactam antibiotic provocation tests
Molina-Molina, G.-J., Gómez-Duque, M., Vidal, X., Agustí, A., Labrador‐Horrillo, M., Luengo, O., Sala-Cunill, A., Galvan‐Blasco, P., Guilarte, M., & Cardona, V. (2024) · World Allergy Organization Journal · doi:10.1016/j.waojou.2024.100914 · Cited by 5
Update on the diagnosis of drug allergy
Cho, Y.-J. (2009) · The Korean Journal of Internal Medicine · Cited by 5
Diagnosis of drug causality in non-immediate drug hypersensitivity in children
Graham, F. J., & Caubet, J. (2018) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2018.1494570 · Cited by 5
Expert opinion: The clinical usefulness of skin tests prior to the administration of beta-lactam antibiotics
Kim, S., Kim, S., Kim, S., Park, J., Park, H. J., Suh, D. I., Sim, D. W., Yang, M. S., Lee, J., Lee, H. Y., et al. (2022) · Allergy Asthma & Respiratory Disease · doi:10.4168/aard.2022.10.1.3 · Cited by 4
Oral amoxicillin-associated anaphylaxis, 1 year after negative penicillin testing and oral amoxicillin challenge
Urriola, N., Paganini, L., Riminton, S., & Limaye, S. (2016) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2016.01.014 · Cited by 3
Penicillin and Cephalosporin-Induced Anaphylaxis: an Update
Doña, I., Bogas, G., Pérez‐Sánchez, N., Fernández, T. D., Moreno, E., & Torres, M. J. (2018) · Current Treatment Options in Allergy · doi:10.1007/s40521-018-0172-6 · Cited by 3
QUESTION 1: What is the risk of a repeat reaction to amoxicillin or a cephalosporin in children with a history of a non-immediate reaction to amoxicillin?
Grinlington, L., Cranswick, N., & Gwee, A. (2016) · Archives of Disease in Childhood · doi:10.1136/archdischild-2016-312089 · Cited by 3
Antibiotic Skin Testing in the Intensive Care Unit: A Systematic Review
Alharbi, H. A. (2019) · Critical Care Nurse · doi:10.4037/ccn2019207 · Cited by 3
Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis
Krishna, M. T., Jani, Y. H., Williams, I., Mújica-Mota, R., Bestwick, R., Siciliano, M., West, R. M., Bhogal, R., Ng, B. Y., Kildonaviciute, K., et al. (2025) · Health and Social Care Delivery Research · doi:10.3310/mtyw6557 · Cited by 2
De-labeling Beta-lactam in Adult Population
Rosado, A., Nieto-Nieto, A., Moreno, A. G., Alonso, M. D., Tejedor-Alberti, A., & Tejedor, M. A. (2022) · Current Treatment Options in Allergy · doi:10.1007/s40521-022-00316-3 · Cited by 2
Allergic and non-allergic hypersensitivity to antibiotics. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology
Kurek, M., Poziomkowska‐Gęsicka, I., & Wiśniewska, M. (2018) · Alergologia Polska - Polish Journal of Allergology · doi:10.5114/pja.2018.74445 · Cited by 1
Resensitization of β-Lactams After Negative Initial Standard Evaluation: A Systematic Review and Meta-Analysis
Srisuwatchari, W., Kulalert, P., Krikeerati, T., Kanchanapoomi, K., Phinyo, P., & Sompornrattanaphan, M. (2026) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2026.02.012 · Cited by 1
AN UPDATE ON THE MANAGEMENT OF ANTIBIOTIC ALLERGY IN CHILDREN
Caubet, J., & Eigenmann, P. (2013) · Cited by 1
Reply
Caubet, J., & Eigenmann, P. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.11.028 · Cited by 1
약물 알레르기의 진단
조영주 (2009) · Cited by 1
Diagnostic challenges, the evaluation of antibiotic allergy
O’Keefe, A., & Ben‐Shoshan, M. (2017) · Current Opinion in Otolaryngology & Head & Neck Surgery · doi:10.1097/moo.0000000000000365
Current awareness: Pharmacoepidemiology and drug safety
(2008) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1488
Primary care physicians present a gap of knowledge regarding the management of penicillin allergy
Faitelson, Y., & Beigelman, A. (2022) · Pediatric Allergy and Immunology · doi:10.1111/pai.13857
Delayed hypersensitivity reaction to penicillin can be lost (and gained): Skin test resensitization following prolonged oral provocation test
Goh, J. Y., & Lee, H. Y. (2025) · Asia Pacific Allergy · doi:10.5415/apallergy.0000000000000220
Examining implementation of the first risk stratification-based programme for evaluating penicillin allergy labels in Western Norway hospitals: a study protocol
Alnæs, M., Oppegaard, O., Kittang, B., Kleppe, L. K., & Storaas, T. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-105425

Authors: Goldberg, A., & Confino-Cohen, R.
Affiliations: Tel Aviv University (IL)
Corresponding author: Goldberg, Arnon
Venue: Annals of Allergy, Asthma & Immunology
Publisher: Elsevier BV
Published: 2008-01
Volume: 100
Issue: 1
Pages: 37-43
ISSN: 1081-1206 (ISSN-L)
DOI: 10.1016/s1081-1206(10)60402-4
OpenAlex: W2015194386
Cited by: 83
References: 35
Citations by year: 2026: 1 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 1 · 2019: 9 · 2018: 10 · 2017: 6 · 2016: 4 · 2015: 3 · 2014: 6 · 2013: 4 · 2012: 1
FWCI: 3.97
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Annals of Allergy Asthma & Immunology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
Keywords: penicillin allergy, penicillin skin testing, drug tolerance, amoxicillin, drug hypersensitivity diagnosis, adverse drug reactions
MeSH terms: Administration, Oral, Adolescent, Adult, Aged, Aged, 80 and over, Amoxicillin, Ampicillin, Child, Child, Preschool, Drug Hypersensitivity, Female, Follow-Up Studies, Humans, Male, Middle Aged, Penicillin G, Penicillin V, Penicillins, Predictive Value of Tests, Prospective Studies, Skin Tests, Benzeneacetamides

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Skin testing and oral penicillin challenge in patients with a history of remote penicillin allergy.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks