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Control of sporulation initiation in Bacillus subtilis
Abstract
Recent work has provided new insights into the mechanisms by which Bacillus subtilis responds to signals that reflect high population density and nutritional limitation, the mechanisms that regulate activation of the key transcription factor Spo0A, and the physical basis for critical aspects of the Spo0A phosphorelay.
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“The cell itself is unable to discriminate, whether sporulation is initiated by nutrient limitation or quorumsensing signals (Sonenshein 2000).”
From Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium (2024) · cites this paper as Sonenshein 2000
In the citing paper
“Authors report that sporulation is initiated at cell concentration of approximately 10 8 cells/mL (Sonenshein 2000; Posada-Uribe et al. 2015).”
From Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium (2024) · cites this paper as Sonenshein 2000
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Research works printed but not linked: 43
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“The cell itself is unable to discriminate, whether sporulation is initiated by nutrient limitation or quorum-sensing signals (Sonenshein 2000).”
Metadata
- Authors
- Sonenshein, A. L.
- Affiliations
- Tufts University (US)
- Corresponding author
- Sonenshein, Abraham L
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2000-12
- Volume
- 3
- Issue
- 6
- Pages
- 561-566
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W2035699290
- Cited by
- 252
- References
- 0
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 6 · 2023: 11 · 2022: 10 · 2021: 12 · 2020: 10 · 2019: 13 · 2018: 9 · 2017: 9 · 2016: 15 · 2015: 15 · 2014: 17 · 2013: 7 · 2012: 6
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of General Medical Sciences (GM42210)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
- Keywords
- sporulation initiation, Bacillus subtilis, Spo0A, phosphorelay, nutrient limitation, transcriptional regulation, quorum sensing
- MeSH terms
- Bacillus subtilis, Bacterial Proteins, Spores, Bacterial, Transcription Factors, Transcription, Genetic, Gene Expression Regulation, Bacterial
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