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Prognostic Value of 6-Minute Walk Corridor Test in Patients with Mild to Moderate Heart Failure: Comparison with Other Methods of Functional Evaluation
Abstract
Aim: The study was designed to evaluate the prognostic value of the 6-min walk test (6MWT) in patients with mild to moderate congestive heart failure (CHF). Methods and results: Two hundred and fourteen patients (119 men and 95 women, mean age 64 years) were followed for a mean period of 34 months to assess event-free survival (death, heart transplantation). Sixty-six patients (34%) died (63 cardiovascular causes, 2 cancer and 1 stroke) and five patients underwent heart transplantation. For patients who walked <300 m during the 6MWT, survival was 62% compared with 82% in patients who walked 300–450 m or>450 m. With univariate analysis, NYHA class was the strongest predictor of death. LVEF (P<0.0001), aetiology of heart failure (P<0.001), LV filling pattern (P=0.002) and 6MWT distance (P<0.01) were all significantly related to survival. No significant relationship was found between survival, peak oxygen consumption or anaerobic threshold. Multivariate analysis using the Cox-stepwise regression model showed that LV fractional shortening (P<0.009) and 6MWT distance (P<0.0005) were the strongest prognostic markers. Conclusion: A 6MWT distance of <300 m is a simple and useful prognostic marker of subsequent cardiac death in unselected patients with mild to moderate CHF.
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Cited by
Heidenreich, P. A., Bozkurt, B., Aguilar, D., Allen, L. A., Byun, J. J., Colvin, M. M., Deswal, A., Drazner, M. H., Dunlay, S. M., Evers, L. R., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001063 · Cited by 4,922
Spruit, M. A., Singh, S. J., Garvey, C., ZuWallack, R., Nici, L., Rochester, C., Hill, K., Holland, A. E., Lareau, S. C., Man, W. D.-C., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201309-1634st · Cited by 3,938
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure
Heidenreich, P. A., Bozkurt, B., Aguilar, D., Allen, L. A., Byun, J. J., Colvin, M. M., Deswal, A., Drazner, M. H., Dunlay, S. M., Evers, L. R., et al. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.12.012 · Cited by 2,862
Arena, R., Myers, J., Williams, M. A., Gulati, M., Kligfield, P., Balady, G. J., Collins, E., & Fletcher, G. (2007) · Circulation · doi:10.1161/circulationaha.106.184461 · Cited by 727
Mezzani, A., Hamm, L. F., Jones, A. M., McBride, P. E., Moholdt, T., Stone, J. A., Urhausen, A., & Williams, M. A. (2013) · European Journal of Preventive Cardiology · doi:10.1177/2047487312460484 · Cited by 550
Metadata
- Authors
- Rostagno, C., Olivo, G., Comeglio, M., Boddi, V., Banchelli, M., Galanti, G., & Gensini, G. F.
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-06-01
- Volume
- 5
- Issue
- 3
- Pages
- 247-252
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W1975699879
- Cited by
- 305
- References
- 0
- FWCI
- 6.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Prognostic Value of 6-Minute Walk Corridor Test in Patients with Mild to Moderate Heart Failure: Comparison with Other Methods of Functional Evaluation. https://app.cochat.ai/papers/10.1016/s1388-9842(02)00244-1
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- Rostagno, C., Olivo, G., Comeglio, M., Boddi, V., Banchelli, M., Galanti, G., & Gensini, G. F. (2003). Prognostic Value of 6-Minute Walk Corridor Test in Patients with Mild to Moderate Heart Failure: Comparison with Other Methods of Functional Evaluation. European Journal of Heart Failure. https://doi.org/10.1016/s1388-9842(02)00244-1
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