Membrane damage is at the core of Alzheimer's disease
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
TREM2 binds lipids exposed on the surface of apoptotic cells, as well as ApoE and lipidated Amyloid beta (Aβ).
“TREM2 binds lipids exposed on the surface of apoptotic cells [49, 50], as well as ApoE [51] and lipidated Amyloid beta (Aβ) [52].”
From TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation (2021) · cites this paper as [49]
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Magno, L., Bunney, T. D., Mead, E., Svensson, F., & Bictash, M. N. (2021) · Molecular Neurodegeneration · doi:10.1186/s13024-021-00436-5 · Cited by 64 · see citing works
- Authors
- Hardy, J.
- Affiliations
- UCL Queen Square Institute of Neurology (GB)
- Corresponding author
- Hardy, John
- ORCID
- Hardy, John
- Venue
- The Lancet Neurology
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 16
- Issue
- 5
- Pages
- 342
- ISSN
- 1474-4422 (ISSN-L)
- OpenAlex
- W2607311694
- Cited by
- 18
- References
- 0
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 3 · 2017: 1
- FWCI
- 1.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Parkinson's UK (G-1307)
- Rosetrees Trust
- Medical Research Council (MR/K01417X/1, MR/L501542/1, MR/J004758/1)
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- Alzheimer's disease, membrane damage, amyloid deposition, late-onset Alzheimer's disease, sporadic Alzheimer's disease, autosomal dominant Alzheimer's disease, apolipoprotein E, genetic loci, pathogenesis
- MeSH terms
- Alzheimer Disease, Cell Membrane, Humans, Immunity, Innate, Neurons, Lipid Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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