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Cited by 372Anesthesia and Sedative AgentsCardiac, Anesthesia and Surgical OutcomesAnesthesia and Pain Management

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study

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Kirmeier, Eva, Eriksson, Lars I, Lewald, Heidrun, Jonsson Fagerlund, Malin, Hoeft, Andreas, Hollmann, Markus, Meistelman, Claude, Hunter, Jennifer M, Ulm, Kurt, Blobner, Manfred, Abad Gurumeta, Alfredo, Abernethy, Caroline, Abigail, Patrick, Achaibar, Kira, Adam, Emily, Afshari, Arash, Agudelo Montoya, M. Elizabeth, Akgün, Fatma Nur, Aletti, Gabriele, Alkış, Neslihan, Allan, Katie, Allan, Ashley, Allaouchiche, Bernard, Allcock, Clare, Almasy, Emoke, Amey, Isobel, Amigoni, Maria, Andersen, Elin, Andersson, Peder, Anipchenko, Natalya, Antunes, Pedro, Armstrong, Earlene, Aslam, Tayyba Naz, Aslin, Bjorn, Assunção, José Pedro, Ausserer, Julia, Avvai, Mary, Awad, Nahla, Ayas Montero, Begoña, Ayuso, Mercedes, Azevedo, Patricia, Badarau, Victoria, Badescu, Roxana, Baiardo Redaelli, Martina, Baird, Colin, Baird, Yolanda, Baker, Tim, Balaji, Packianathaswamy, Bălan, Cristina, Balandin, Alina, Balescu-Arion, Carmen, Baliuliene, Vilda, Baltasar Isabel, Jorge, Baluch, Saif Nasr, Bandrabur, Daniela, Bankewitz, Carla, Barber, Katrina, Barbera, Francesco, Barcraft-Barnes, Helena, Barletti, Valentina, Barnett, Gill, Baron, Kirsty, Barros, Ana, Barsan, Victoria, Bartlett, Pauline, Batistaki, Chrysanthi, Baumgarten, Georg, Baytas, Volkan, Beauchamp, Nigel, Becerra Cayetano, Isabel A., Bell, Stephanie, Bellandi, Mattia, Belletti, Alessandro, Belmonte Cuenca, Julio, Benitez-Cano, Adela, Beretta, Luigi, Berger, Marc, Bergmann, Nicole, Bergmark, Kristina, Bermudez Lopez, Maria, Bernotaite, Monika, Beurskens, Charlotte, Bidd, Heena, Bifulco, Francesca, Bignami, Elena, Bilic, Aleksandar, Bilskiene, Diana, Bischoff, Petra, Bishop, Luke, Bjonness, Therese, Blaylock, Hether, Blethyn, Kate, Blincoe, Thomas, Blokhin, Ivan, Blunt, Nadia, Boer, Christa, Bois, Grégory, Bonicolini, Eleonora, Booth, Joanna, Borecka-Kedzierska, Miroslawa, Borstnar, Katarina, Borys, Michał, Boselli, Emmanuel, Bouvet, Lionel, Bouwman, Arthur, Bowen, Leonora, Bowrey, Sarah, Boxall, Leigh, Božić, Teodora, Bradley, Tom, Branco, Teresa, Brazzi, Luca, Brazzoni, Marcella, Brear, Tracy, Brogly, Nicolas, Brohi, Farooq, Broms, Jacob, Bubliauskas, Andrius, Bucolo, Gea Erika, Buerkle, Hartmut, Buggy, Donal, Buhre, Wolfgang, Bukauskas, Tomas, Butturini, Francesco, Byttner, Anders, Cabrera Díaz, Itahísa, Calderon, Adriana, Calhau, Ricardo, Callejo, Angel, Cammu, Guy, Campesato, Manuela, Can, Özlem S, Candeias, Margarida, Cantor, Andreea, Carise, Elsa, Carmona, Cristina, Carreteiro, Joana, Carrieri, Cosima, Carter, Anna, Casal, Manuela, Casanova, Irene, Cascella, Marco, Casero, Luis M., Casiraghi, Guiseppina Maria, Castelo-Branco, Laila, Castro Arranz, Carlos, Cernea, Daniela Denisa, Cervantes, Jesoporiol, Chandler, Ben, Charnock, Robert, Chatzimicali, Aikaterini, Chinery, Elane, Chishti, Ahmed, Chondhury, Priyakam, Christie, Emily, Christodoudiles, George, Ciardo, Stefano, Cimpeanu, Luminata, Cindea, Iulia, Cinnella, Gilda, Clark, Sebastian, Clayton, Matthew, Cocu, Simona, Collyer, Thomas, Colvin, Carie, Cope, Sean, Copeta, Filomena, Copotoiu, Sanda-Maria, Correia de Barros, Filinto, Corso, Ruggero Massimo, Cortegiani, Andrea, Costa, Gabriela, Cowton, Amanda, Cox, Nicolas, Craig, James, Cricca, Valentina, Cronin, John, Cunha, Mariana, Cuomo, Arturo, Curley, Katherine, Czuczwar, Mirosław, Dabrowska, Domenika, Damster, Sabrine, Danguy des Déserts, Marc, Daniliuc, Aura, Danninger, Thomas, Darwish, Imad, Dascalu, Corina, Davies, Kirsty, Davies, Simon, De Boer, Hans, De Flaviis, Adelisa, De Selincourt, Gabrielle, Deana, Cristian, Debaene, Bertrand, Debreceni, Gabor, Dedhia, Jatin, Delgado Garcia, Isabel, Della Rocca, Giorgio, Delroy-Buelles, Llana, Desai, Tejal, Dhillon, Parveen, Di Giacinto, Ida, Di Mauro, Piero, Diaz Gomez, Tamara V., Dimitrovski, Aleksandar, Dinic, Vesna, Dîrzu, Dan-Sebastian, Divander, Mona Britt, Dolinar, Janez, Domingues, Susana, Doolan, James, Downes, Charlotte, Dragoescu, Nicoleta Alice, Droc, Gabriela, Dum, Elisabeth, Dumitrescu, Alexandra, Duncan, Louise, Dzurňáková, Paul, Eberl, Susanne, Edwards, Jayne, Edwards, Mark, Ekelund, Kim, Ekengren, Patrik, Elghouty, Eyad, Ellerkmann, Richard, Ellis, Helen, Elme, Andreas, Ernst, Thomas, Errando, Carlos Luis, Estenes, Simao, Ewaldsson, Callis, Farid, Nahla, Featherstone, James, Febres, Daniela, Fedorov, Sergey, Feggeler, Johanna, Feijten, Prisca, Fellmann, Tobias, Fernandez Candil, Juan, Fernandez Castineira, Ana, Fernández Castineira, Juan, Fernando, Aruna, Ferrando, Carlos, Ferreira, Leonia, Ferreira, Patrick, Feyling, Anders, Filipescu, Daniela, Fleischer, Andreas, Floris, Leda, Foerster, Urs, Fox, Benjamin, Franke, Uwe, Frasca, Denis, Frey, Christian, Frost, Victoria, Fullin, Giorgio, Fumagalli, Jacopo, Furneval, Julie, Fusari, Maurizio, Gallacher, Stuart, Galushka, Svetlana, Gambale, Giorgio, Gambino, Irene, Garcia-Perez, Maria Luisa, Garg, Sanjeev, Garlak, Justyna, Gavranovic, Zeljka, Gavrilov, Roman, Gaynor, Lames, Gecaj Gashi, Agreta, Georghiou, Maria, Gerjevic, Bozena, Gferer, Gudrun, Giarratano, Antonino, Gibson, Andy, Gievski, Vanja, Giles, Julian, Gillberg, Lars, Gilowska, Katarzyna, Gilsanz Rodriguez, Fernando, Gioia, Antonio, Giovannoni, Cecilia, Girotra, Vandana, Gkinas, Dimitrios, Gkiokas, George, Godoroja, Daniela, Goebel, Ulrich, Goel, Vandana, Gonzalez, Matilde, Goranovic, Tatjana, Gornik-Wlaszczuk, Ewa, Gosavi, Smita, Gottfridsson, peter, Gottschalk, André, Granell, Manuel, Granstrom, Anna, Grassetto, Alberto, Greenwood, Anna, Grigoras, Ioana, Grintescu, Ioana, Gritsan, Alexey, Gritsan, Galina, Grynyuk, Andriy, Guadagnin, Giovanni Maria, Guarnieri, Marcello, Güçlü, Çiğdem, Guerrero Diez, Maria, Gunenc, Ferim, Günther, Ulf, Gupta, Pawan, Guttenthaler, Vera, Hack, Yvonne, Hafisayena, Ade, Hagau, Natalia, Haldar, Jagannath, Hales, Dawn, Hancı, Volkan, Hanna-Jumma, Sameer, Harazim, Hana, Harlet, Pierre, Harper, Daniel, Harris, Benjamin, Harvey, Orla, Hashimi, Medita, Hawkins, Lesley, Hayes, Conrad, Heaton, James, Heier, Tom, Helliwell, Laurence, Hemmes, Sabrine, Henderson, Kate, Hermanides, Jeroen, Hermanns, Henning, Herrera Hueso, Berta, Hestenes, Siv, Hettiarachchi, Roshane, Highgate, Judith, Hodgson, Keith, Hoelbling, Daniel, Holland, Jonathan, Horhota, Lucian, Hormis, Anil, Hribar, Renata, Hua, Alina, Humphreys, Sally, Humphries, Ryan, Humpliková, Simona, Hunt, 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Martina, Köstenberger, Markus, Kotzinger, Oskar, Kovačević, Marko, Kranke, Peter, Kranke, Eva, Kraus, Christiane, Kraus, Stephanie, Kubitzek, Christiane, Kucharski, Rafal, Kucukguclu, Semih, Kudrashou, Allaksandr, Kumar, Vinayak, Kummen, Live, Kunit, Cornelia, Kushakovsky, Vlad, Kuvaki, Bahar, Kuzmanovska, Biljana, Kyttari, Aikaterina, Landoni, Giovanni, Lau, Gary, Lazarev, Konstantin, Legett, Samantha, Legrottaglie, Anna Maria, Leonardi, Silvia, Leong, Maria, Lercher, Helene, Leuvrey, Matthieu, Leva, Brigitte, Levstek, Meta, Limb, James, Lindholm, Espen, Linton, Fiona, Liperi, Corradero, Lipski, Fabian, Lirk, Philipp, Lisi, Alberto, Lišková, Katarina, Lluch Oltra, Aitana, Loganathan, Vinothan, Lombardi, Stefania, Lopez, Eloisa, Lopez Rodríguez, Maria, Lorenzini, Laura, Lowicka, Malgorzata, Lugovoy, Alexander, Luippold, Madeleine, Lumb, Andrew, Macas, Andrius, Macgregor, Mark, Machado, Humberto, Maciariello, Maria, Madeira, Isabel, Maitan, Stefan, Majewski, Jacek, Maldini, Branka, 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Claire, Montillo, Gerardo, Moore, Sally, Moore, Faye, Moreira, Zelia, Moreno, Tania, Moreno, Ricardo, Moret, Enrique, Moreton, Sarah, Morgan, Marianne, Moro Velasco, Concepción, Morri, Davide, Moull, Alice, Moura, Fernando, Mráz, Peter, Mrozek, Katarzyna, Mukhtar, Karim, Muniyappa, Sudeshkumar, Murray, Heather, Murthy, Burra VS, Mushambi, Mary, Nadolski, Maria, Nardelli, Pasquale, Nardin, Giordano, Navarro Pérez, Rosalía, Naveiro, Andrea, Negri, Manuela, Nesek Adam, Visnja, Neskovic, Vojislava, Neuwersch, Stefan, Neves, Miriam, Nguyen, Bavinh, Ní Eochagáin, Aisling, Nicholas, Caroline, Nightingale, Jeremy, Norrie, Kylie, Novak-Jankovic, Vesna, Novakova, Andrea, Novillo, Marta, Numan, Sandra, Oduro-Dominah, Louise, Oldner, Anders, Oliveira, Isabel, Ologoiu, Daniela, Oloktsidou, Irini, O'Reilly, Rosalind, Orlando, Alessandro, Ovezov, Alexey, Ozbilgin, Sule, Paal, Peter, Padin Barreiro, Lidia, Palugniok, Ryszard, Papaioannou, Alexandra, Papapostolou, Konstantinos, Paranthaman, Prabhakar, 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Agostina, Wade, Andrew, Wallberg, Hanna, Wallden, Jakob, Wallner, Johann, Walther Sturesson, Louise, Watson, Davina, Weber, Stefan, Wegiel Leskiewiq, Anna, Weller, Debbie, Wensing, Carine, Werkmann, Markus, Westberg, Henrik, Wikström, Erik, Williams, Benedict, Williams, Benedict, Wilson, Robin, Wirth, Steffen, Wittmann, Maria, Wood, Laura, Wright, Stella, Zachoval, Christian, Zambon, Massimo, Zampieri, Silvia, Zampone, Salvatore, Zangrillo, Alberto, Zani, Gianluca, Zavackiene, Asta, Zieglerder, Raphael, Zonneveldt, Harry, Zsisku, Lajos, Zucker, Tom-Philipp, Żukowski, Maciej, Zuleika, Mehrun, Zupanĕiĕ, Darja·2019·The Lancet Respiratory Medicine
DOI 10.1016/s2213-2600(18)30294-7
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Abstract

Background Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use of neuromuscular blocking agents is associated with postoperative pulmonary complications.Methods We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in 28 European countries. We included patients (aged ≥18 years) who received general anaesthesia for any in-hospital procedure except cardiac surgery. Patient characteristics, surgical and anaesthetic details, and chart review at discharge were prospectively collected over 2 weeks. Additionally, each patient underwent postoperative physical examination within 3 days of surgery to check for adverse pulmonary events. The study outcome was the incidence of postoperative pulmonary complications from the end of surgery up to postoperative day 28. Logistic regression analyses were adjusted for surgical factors and patients' preoperative physical status, providing adjusted odds ratios (OR adj) and adjusted absolute risk reduction (ARR adj). This study is registered with ClinicalTrials.gov, number NCT01865513.Findings Between June 16, 2014, and April 29, 2015, data from 22 803 patients were collected. The use of neuromuscular blocking agents was associated with an increased incidence of postoperative pulmonary complications in patients who had undergone general anaesthesia (1658 [7·6%] of 21 694); OR adj 1·86, 95% CI 1·53-2·26; ARR adj -4·4%, 95% CI -5·5 to -3·2). Only 2·3% of high-risk surgical patients and those with adverse respiratory profiles were anaesthetised without neuromuscular blocking agents. The use of neuromuscular monitoring (OR adj 1·31, 95% CI 1·15-1·49; ARR adj -2·6%, 95% CI -3·9 to -1·4) and the administration of reversal agents (1·23, 1·07-1·41; -1·9%, -3·2 to -0·7) were not associated with a decreased risk of postoperative pulmonary complications. Neither the choice of sugammadex instead of neostigmine for reversal (OR adj 1·03, 95% CI 0·85-1·25; ARR adj -0·3%, 95% CI -2·4 to 1·5) nor extubation at a train-of-four ratio of 0·9 or more (1·03, 0·82-1·31; -0·4%, -3·5 to 2·2) was associated with better pulmonary outcomes.Interpretation We showed that the use of neuromuscular blocking drugs in general anaesthesia is associated with an increased risk of postoperative pulmonary complications. Anaesthetists must balance the potential benefits of neuromuscular blockade against the increased risk of postoperative pulmonary complications.Funding European Society of Anaesthesiology.

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Kirmeier, E., Eriksson, L. I., Lewald, H., Jonsson Fagerlund, M., Hoeft, A., Hollmann, M., Meistelman, C., Hunter, J. M., Ulm, K., Blobner, M., Abad Gurumeta, A., Abernethy, C., Abigail, P., Achaibar, K., Adam, E., Afshari, A., Agudelo Montoya, M. E., Akgün, F. N., Aletti, G., Alkış, N., Allan, K., Allan, A., Allaouchiche, B., Allcock, C., Almasy, E., Amey, I., Amigoni, M., Andersen, E., Andersson, P., Anipchenko, N., Antunes, P., Armstrong, E., Aslam, T. N., Aslin, B., Assunção, J. P., Ausserer, J., Avvai, M., Awad, N., Ayas Montero, B., Ayuso, M., Azevedo, P., Badarau, V., Badescu, R., Baiardo Redaelli, M., Baird, C., Baird, Y., Baker, T., Balaji, P., Bălan, C., Balandin, A., Balescu-Arion, C., Baliuliene, V., Baltasar Isabel, J., Baluch, S. N., Bandrabur, D., Bankewitz, C., Barber, K., Barbera, F., Barcraft-Barnes, H., Barletti, V., Barnett, G., Baron, K., Barros, A., Barsan, V., Bartlett, P., Batistaki, C., Baumgarten, G., Baytas, V., Beauchamp, N., Becerra Cayetano, I. A., Bell, S., Bellandi, M., Belletti, A., Belmonte Cuenca, J., Benitez-Cano, A., Beretta, L., Berger, M., Bergmann, N., Bergmark, K., Bermudez Lopez, M., Bernotaite, M., Beurskens, C., Bidd, H., Bifulco, F., Bignami, E., Bilic, A., Bilskiene, D., Bischoff, P., Bishop, L., Bjonness, T., Blaylock, H., Blethyn, K., Blincoe, T., Blokhin, I., Blunt, N., Boer, C., Bois, G., Bonicolini, E., Booth, J., Borecka-Kedzierska, M., Borstnar, K., Borys, M., Boselli, E., Bouvet, L., Bouwman, A., Bowen, L., Bowrey, S., Boxall, L., Božić, T., Bradley, T., Branco, T., Brazzi, L., Brazzoni, M., Brear, T., Brogly, N., Brohi, F., Broms, J., Bubliauskas, A., Bucolo, G. E., Buerkle, H., Buggy, D., Buhre, W., Bukauskas, T., Butturini, F., Byttner, A., Cabrera Díaz, I., Calderon, A., Calhau, R., Callejo, A., Cammu, G., Campesato, M., Can, Ö. S., Candeias, M., Cantor, A., Carise, E., Carmona, C., Carreteiro, J., Carrieri, C., Carter, A., Casal, M., Casanova, I., Cascella, M., Casero, L. M., Casiraghi, G. M., Castelo-Branco, L., Castro Arranz, C., Cernea, D. D., Cervantes, J., Chandler, B., Charnock, R., Chatzimicali, A., Chinery, E., Chishti, A., Chondhury, P., Christie, E., Christodoudiles, G., Ciardo, S., Cimpeanu, L., Cindea, I., Cinnella, G., Clark, S., Clayton, M., Cocu, S., Collyer, T., Colvin, C., Cope, S., Copeta, F., Copotoiu, S.-M., Correia de Barros, F., Corso, R. M., Cortegiani, A., Costa, G., Cowton, A., Cox, N., Craig, J., Cricca, V., Cronin, J., Cunha, M., Cuomo, A., Curley, K., Czuczwar, M., Dabrowska, D., Damster, S., Danguy des Déserts, M., Daniliuc, A., Danninger, T., Darwish, I., Dascalu, C., Davies, K., Davies, S., De Boer, H., De Flaviis, A., De Selincourt, G., Deana, C., Debaene, B., Debreceni, G., Dedhia, J., Delgado Garcia, I., Della Rocca, G., Delroy-Buelles, L., Desai, T., Dhillon, P., Di Giacinto, I., Di Mauro, P., Diaz Gomez, T. V., Dimitrovski, A., Dinic, V., Dîrzu, D.-S., Divander, M. B., Dolinar, J., Domingues, S., Doolan, J., Downes, C., Dragoescu, N. A., Droc, G., Dum, E., Dumitrescu, A., Duncan, L., Dzurňáková, P., Eberl, S., Edwards, J., Edwards, M., Ekelund, K., Ekengren, P., Elghouty, E., Ellerkmann, R., Ellis, H., Elme, A., Ernst, T., Errando, C. L., Estenes, S., Ewaldsson, C., Farid, N., Featherstone, J., Febres, D., Fedorov, S., Feggeler, J., Feijten, P., Fellmann, T., Fernandez Candil, J., Fernandez Castineira, A., Fernández Castineira, J., Fernando, A., Ferrando, C., Ferreira, L., Ferreira, P., Feyling, A., Filipescu, D., Fleischer, A., Floris, L., Foerster, U., Fox, B., Franke, U., Frasca, D., Frey, C., Frost, V., Fullin, G., Fumagalli, J., Furneval, J., Fusari, M., Gallacher, S., Galushka, S., Gambale, G., Gambino, I., Garcia-Perez, M. L., Garg, S., Garlak, J., Gavranovic, Z., Gavrilov, R., Gaynor, L., Gecaj Gashi, A., Georghiou, M., Gerjevic, B., Gferer, G., Giarratano, A., Gibson, A., Gievski, V., Giles, J., Gillberg, L., Gilowska, K., Gilsanz Rodriguez, F., Gioia, A., Giovannoni, C., Girotra, V., Gkinas, D., Gkiokas, G., Godoroja, D., Goebel, U., Goel, V., Gonzalez, M., Goranovic, T., Gornik-Wlaszczuk, E., Gosavi, S., Gottfridsson, P., Gottschalk, A., Granell, M., Granstrom, A., Grassetto, A., Greenwood, A., Grigoras, I., Grintescu, I., Gritsan, A., Gritsan, G., Grynyuk, A., Guadagnin, G. M., Guarnieri, M., Güçlü, Ç., Guerrero Diez, M., Gunenc, F., Günther, U., Gupta, P., Guttenthaler, V., Hack, Y., Hafisayena, A., Hagau, N., Haldar, J., Hales, D., Hancı, V., Hanna-Jumma, S., Harazim, H., Harlet, P., Harper, D., Harris, B., Harvey, O., Hashimi, M., Hawkins, L., Hayes, C., Heaton, J., Heier, T., Helliwell, L., Hemmes, S., Henderson, K., Hermanides, J., Hermanns, H., Herrera Hueso, B., Hestenes, S., Hettiarachchi, R., Highgate, J., Hodgson, K., Hoelbling, D., Holland, J., Horhota, L., Hormis, A., Hribar, R., Hua, A., Humphreys, S., Humphries, R., Humpliková, S., Hunt, J., Husnain, A., Hussein, A., Hyams, B., Iannuccelli, F., Ilette, K., Ilyas, C., Inan, T., India, I., Ionițăv, V., Irwin, F., Jain, V., Janez, B., Jankovic, R., Jenkins, S., Jenko, M., Jimenez, R., Jiménez Gomez, B., Joachim, S., Joelsson-Alm, E., John, J., Jonikaite, L., Jovic, M., Jungwirth, B., Junke, E., Kabakov, B., Kadaoui, S.-D., Kanski, A., Karadag, S., Karbonskiene, A., Karjagin, J., Kasnik, D., Katanolli, F., Katsika, E., Kaufmann, K., Keane, H., Kelly, M., Kent, M., Keraitiene, G., Khudhur, A., Khuenl-Brady, K., Kidd, L., King, S., Kirchgäßner, K., Klancir, T., Klucniks, A., Knotzer, J., Knowlden, P., Koers, L., Kompan, J., Koneti, K. K., Kooij, F., Koolen, E., Koopman - van Gemert, A. W. M. M., Kopp, K., Korfiotis, D., Korolkov, O., Kosinová, M., Köstenberger, M., Kotzinger, O., Kovačević, M., Kranke, P., Kranke, E., Kraus, C., Kraus, S., Kubitzek, C., Kucharski, R., Kucukguclu, S., Kudrashou, A., Kumar, V., Kummen, L., Kunit, C., Kushakovsky, V., Kuvaki, B., Kuzmanovska, B., Kyttari, A., Landoni, G., Lau, G., Lazarev, K., Legett, S., Legrottaglie, A. M., Leonardi, S., Leong, M., Lercher, H., Leuvrey, M., Leva, B., Levstek, M., Limb, J., Lindholm, E., Linton, F., Liperi, C., Lipski, F., Lirk, P., Lisi, A., Lišková, K., Lluch Oltra, A., Loganathan, V., Lombardi, S., Lopez, E., Lopez Rodríguez, M., Lorenzini, L., Lowicka, M., Lugovoy, A., Luippold, M., Lumb, A., Macas, A., Macgregor, M., Machado, H., Maciariello, M., Madeira, I., Maitan, S., Majewski, J., Maldini, B., Malewski, G., Manfredini, L., Männer, O., Marchand, B., Marcu, A., Margalef, J., Margarson, M., Marinheiro, L., Markic, A., Markovic Bozic, J., Marrazzo, F., Martin, J., Martin Ayuso, M., Martinez, E., Martino, E. A., Martinson, V., Marusic-Gaser, K., Mascarenhas, C., Mathis, C., Matsota, P., Mavrommati, E., Mazul Sunko, B., McCourt, K., McGill, N., McKee, R., Meço, B. C., Meier, S., Melbourne, S., Melbybråthen, G., Meli, A., Melia, A., Melotti, R. M., Menga, M. R., Mercer, P., Merotra, S., Mescolini, S., Metterlein, T., Michalov, M., Michlig, S., Midgley, S., Milić, M., Milojevic, M., Miñana, A., Minto, G., Mirabella, L., Mirea, L., Mittelstädt, L., Moeglen, A., Moise, A., Mokini, Z., Molin, A., Moltó, L., Monea, M. C., Montalto, F., Montgomery, J., Montgomery, C., Montillo, G., Moore, S., Moore, F., Moreira, Z., Moreno, T., Moreno, R., Moret, E., Moreton, S., Morgan, M., Moro Velasco, C., Morri, D., Moull, A., Moura, F., Mráz, P., Mrozek, K., Mukhtar, K., Muniyappa, S., Murray, H., Murthy, B. V., Mushambi, M., Nadolski, M., Nardelli, P., Nardin, G., Navarro Pérez, R., Naveiro, A., Negri, M., Nesek Adam, V., Neskovic, V., Neuwersch, S., Neves, M., Nguyen, B., Ní Eochagáin, A., Nicholas, C., Nightingale, J., Norrie, K., Novak-Jankovic, V., Novakova, A., Novillo, M., Numan, S., Oduro-Dominah, L., Oldner, A., Oliveira, I., Ologoiu, D., Oloktsidou, I., O'Reilly, R., Orlando, A., Ovezov, A., Ozbilgin, S., Paal, P., Padin Barreiro, L., Palugniok, R., Papaioannou, A., Papapostolou, K., Paranthaman, P., Pardey Bracho, G., Parente, S., Parfeni, A., Pasin, L., Passey, S., Pastor, E., Patch, S., Patil, A., Paunescu, M.-A., Pehboeck, D., Pereira, M., Pereira, C., Perez Caballero, P., Pérez García, A., Pérez Soto, A., Perez Tejero, G., Perez-Cerda, F., Pesenti, A., Petta, R., Philippe, S., Pickering, D., Pico Veloso, J., Pina, P., Pinho-Oliveira, V., Pinol, S., Pinto, R., Pistidda, L., Pitterle, M., Piwowarczyk, P., Plotnikova, O., Pohl, H., Poldermann, J., Polkovicová, L., Pompei, L., Popescu, M., Popović, R., Pota, V., Potocnik, M., Potręć, B., Potter, A., Pramod, N., Prchalova, M., Preckel, B., Pugh, R., Pulletz, M., Radoeshki, A., Rafi, A., Ragazzi, R., Raineri Santi, M., Rajamanickam, T., Rajput, Z., Ramachandran, R., Ramasamy, R., Ramessur, S., Rao, R., Rasmussen, A., Rato, A., Razaque, U., Real Navacerrada, M. I., Reavley, C., Reid, J., Reschreiter, H., Rial, E., Ribas Carrasco, P., Ribeiro, S., Rich, N., Richardson, L., Rimaitis, K., Rimaitis, M., Ringvold, E.-M., Ripke, F., Ristescu, I., Ritchie, K., Ródenas, F., Rodrigues, P., Rogers, E., Rogerson, D., Romagnoli, S., Romero, E., Rondovic, G., Rose, B. O., Roth, W., Rotter, M.-T., Rousseau, G., Rudjord, A., Rueffert, H., Rundgren, M., Rupprecht, K., Rushton, A., Russotto, V., Rypulak, E., Ryszka, M., Sà, J., Sà Couto, P., Saby, S., Sagic, J., Saleh, O., Sales, G., Sánchez Sánchez, Y., Sanghera, S., Şanli Karip, C., Santiveri Papiol, F. J., Santos, S., Sarno, S., Saul, D., Saunders, D., Savic, N., Scalco, L., Scanlon, D., Schaller, S., Schax, C., Scheffer, G. J., Schening, A., Schiavone, V., Schmidt-Ehrenberg, F., Schmidt-Mutter, C., Schönberg, C., Schopflin, C., Schreiber, J.-U., Schultz, M., Schurig, M., Scott, C., Sebestian, S., Sehgal, S., Sem, V., Semenas, E., Serafini, E., Serchan, P., Shields, M., Shobha, R., Shosholcheva, M., Siamansour, T., Siddaiah, N., Siddiqi, K., Sinclair, R., Singh, P., Singh, R., Sinha, A., Sinha, A., Skinner, A., Smee, E., Smekalova, O., Smith, N., Smith, T., Smitz, C., Smole, D., Sojčić, N., Soler Pedrola, M., Somanath, S., Sonksen, J., Sorella, M. C., Sörmus, A., Soro, M., Soto, C., Spada, A., Spadaro, S., Spaeth, J., Sparr, H., Spielmann, A., Spindler-Vesel, A., Stamelos, M., Stancombe L, L., Stanculescu, A., Standl, T., Standley, T., Stanek, O., Stanisavljević, S., Starczewska, M., Stäuble, C., Steen, J., Stefan, O. M., Stell, E., Stera, C., Stevens, M., Stoerckel, M., Stošić, B., Stourac, P., Stroumpoulis, K., Struck, R., Suarez de la Rica, A., Sultanpori, A., Sundara Rajan, R., Suying, O., Svensen, C., Swan, L., Syrogianni, P., Sysiak, J., Szederjesi, J., Taddei, S., Tan Hao, E., Tanou, V., Tarabová, K., Tardaguila Sancho, P., Tarroso, M., Tartaglione, M., Taylor, E., Tbaily, L., Telford, R., Terenzoni, M., Theodoraki, K., Thornley, H., Tiganiuc, L., Toim, H., Tomescu, D., Tommasino, C., Toni, J., Toninelli, A., Toretti, I., Townley, S., Trepenaitis, D., Trethowan, B., Tsaousi, G., Tsiftsi, A., Tudor, A., Turan, G., Turhan, S. Ç., Unic-Stojanovic, D., Unterbuchner, C., Unzueta, C., Uranjek, J., Ursic, T., Vaida, S., Valldeperas Ferrer, S., Valldeperas Hernandez, M. I., Valsamidis, D., Van Beek, R., Van dasselaer, N., Van Der Beek, T., Van Duivenvoorde, Y., van Klei, W. A., Van Poorter, F., Van Zaane, B., Van Zundert, T., Van Zyl, R., Vargas Munoz, A. M., Varsani, N., Vasconcelos, P., Vassilakis, G., Vecchiatini, T., Vecera, L., Vercauteren, M., Verdouw, B., Verheyen, V., Verri, M., Vicari Sottosanti, L. G., Vico, M., Vidal Mitjans, P., Vilardi, A., Vissicchio, D., Vitale, G., Vitković, B., Vizcaychipi, M. P., Voicu, A., Voje, M., Volfová, I., Volta, C. A., Von Lutterotti, T., von Tiesenhausen, A., Vrecic-Slabe, S., Vukcevic, D., Vukovic, R., Vullo, P. A., Wade, A., Wallberg, H., Wallden, J., Wallner, J., Walther Sturesson, L., Watson, D., Weber, S., Wegiel Leskiewiq, A., Weller, D., Wensing, C., Werkmann, M., Westberg, H., Wikström, E., Williams, B., Williams, B., Wilson, R., Wirth, S., Wittmann, M., Wood, L., Wright, S., Zachoval, C., Zambon, M., Zampieri, S., Zampone, S., Zangrillo, A., Zani, G., Zavackiene, A., Zieglerder, R., Zonneveldt, H., Zsisku, L., Zucker, T.-P., Żukowski, M., Zuleika, M., & Zupanĕiĕ, D.
Affiliations
  • Technical University of Munich (DE)
  • Karolinska University Hospital (SE)
  • University Hospital Bonn (DE)
  • Amsterdam UMC Location University of Amsterdam (NL)
  • University of Liverpool (GB)
Corresponding author
Blobner, Manfred
ORCID
Venue
The Lancet Respiratory Medicine
Publisher
Elsevier BV
Published
2019-02
Volume
7
Issue
2
Pages
129-140
ISSN
2213-2600 (ISSN-L)
DOI
10.1016/s2213-2600(18)30294-7
OpenAlex
W2891017301
Cited by
372
References
38
Citations by year
2026: 35 · 2025: 44 · 2024: 35 · 2023: 51 · 2022: 49 · 2021: 71 · 2020: 54 · 2019: 31
FWCI
57.48
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Lancet Respiratory Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • HAL (submittedVersion)
  • BOA (University of Milano-Bicocca) (submittedVersion)
  • Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
  • Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion)
  • Florence Research (University of Florence) (submittedVersion)
  • IrInSubria (University of Insubria) (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli" (submittedVersion)
  • Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
  • UnissResearch (Università degli Studi di Sassari) (submittedVersion)
  • Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
  • Lithuanian University of Health Sciences (submittedVersion)
  • mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
  • Carl von Ossiezky University of Oldenburg (submittedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
  • Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, other-oa)
Funders
  • National Institute for Health and Care Research (ACF-2017-17-016)
  • European Society of Anaesthesiology
Topics
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
Keywords
neuromuscular blocking agents, general anesthesia, postoperative pulmonary complications, neuromuscular monitoring, neuromuscular reversal agents, sugammadex, neostigmine, postoperative respiratory failure, postoperative pneumonia, postoperative atelectasis, postoperative pleural effusion
MeSH terms
Adult, Aged, Anesthesia, General, Cause of Death, Europe, Female, Humans, Lung Diseases, Male, Middle Aged, Neuromuscular Blocking Agents, Postoperative Complications, Prospective Studies, Retrospective Studies, Cohort Studies, Logistic Models, Odds Ratio, Survival Analysis, Hospital Mortality, Risk Assessment

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