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Cited by 292Phytochemicals and Medicinal PlantsMedicinal Plants and NeuroprotectionMedicinal Plant Research

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Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review

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Alok, Shashi, Jain, Sanjay Kumar, Verma, Amita, Kumar, Mayank, Mahor, Alok, Sabharwal, Monika·2013·Asian Pacific Journal of Tropical Disease
DOI 10.1016/s2222-1808(13)60049-3PMC PMC4027291
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Abstract

Asparagus racemosus (A. racemosus) belongs to family Liliaceae and commonly known as Satawar, Satamuli, Satavari found at low altitudes throughout India. The dried roots of the plant are used as drug. The roots are said to be tonic and diuretic and galactgogue, the drug has ulcer healing effect probably via strenthening the mucosal resistance or cytoprotection. It has also been identified as one of the drugs to control the symotoms of AIDS. A. racemosus has also been successfully by some Ayurvedic practitioner for nervous disorder, inflammation and certain infectious disease. However, no scintific proof justify aborementioned uses of root extract of A. racemosus is available so far. Recently few reports are available demonstrating beneficial effects of alcoholic and water extract of the roots of A. racemosus in some clinical conditions and experimentally indused disease e.g. galactogougue affects, antihepatotoxic, immunomodulatory effects, immunoadjuvant effect, antilithiatic effect and teratogenicity of A. racemosus. The present artical includes the detailed exploration of pharmacological properties of the root extract of A. racemosus reported so far.

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  1. Sairam, 2003, Gastroduodenal ulcer protective activity of Asparagus racemosus. An experimental, biochemical and histological study, J Ethnopharmacol, 86, 1, 10.1016/S0378-8741(02)00342-2 · DOI
  2. Kamat, 2000, Antioxdant properties of Asparagus racemosus against damagedinduced by gamma radiation on rat liver mitochondria, J Ethanopharmacol, 71, 425, 10.1016/S0378-8741(00)00176-8 · DOI
  3. Goyal, 2003, Asparagus racemosus an update, Indian J Med Sci, 57, 408
  4. Gaitonde, 1969, Antioxytocic action of saponin isolated from Asparagus racemosus Willd (Shatavari) on uterine muscle, Arch Int Pharmacodyn Ther, 179, 121
  5. Joshi, 1988, Chemistry of Ayurvedic crude drugs: Part VIII: Shatavari 2. Structure elucidation of bioactive shatavarin I and other glycosides, Indian J Chem Section B Organ Chem, 27, 12
  6. Nair, 1969, Occurrence of diosgenin in Asparagus racemosus, Curr Sci, 17, 414
  7. Patricia, 2006, Asparinins, asparosides, curillins, curillosides and shavatarins. Structural clarication with the isolation of shatavarin V, a new steroidal saponin from the root of Asparagus racemosus, Tetrahed Lett, 47, 8683, 10.1016/j.tetlet.2006.10.030 · DOI
  8. Sekine, 1994, Fukasawa Structure of asparagamine A, a novel polycyclic alkaloid from Asparagus racemosus, Chem Pharm Bull Tokyo, 42, 1360, 10.1248/cpb.42.1360 · DOI
  9. Kukasawa, 1994, Structure of asparagamine A, a novel polycyclic alkaloid from Asparagus racemosus, Chem Pharm Bull, 42, 1360, 10.1248/cpb.42.1360 · DOI
  10. Sekine, 1995, TIFFNal structure and relative stereochemistry of a new polycyclic alkaloid, asparagamine A, showing anti-oxytocin activity, isolated from Asparagus racemosus, J Chem Soc, 1, 391
  11. Saxena, 2001, A new isoflavone from the roots of Asparagus racemosus, Fitoterapia, 72, 307, 10.1016/S0367-326X(00)00315-4 · DOI
  12. Boger, 1985, Antimicrobial and cytotoxic properties of 9, 10-dihydrophenanthrenes: structure-activity studies on juncusol, J Med Chem, 28, 1543, 10.1021/jm00148a031 · DOI
  13. Sekine, 1997, 9, 10-dihydrophenanthrene from Asparagus racemosus, Phytochemistry, 44, 763, 10.1016/S0031-9422(96)00579-1 · DOI
  14. Wiboonpun, 2004, Identification of antioxidant compound from Asparagus racemosus, Phytother Res, 8, 771, 10.1002/ptr.1526 · DOI
  15. Acharya, 2012, Antioxidant and hepatoprotective action of Asparagus racemosus Willd. root extracts, Indian J Exp Biol, 50, 795
  16. Sharma, 1981, Constituents of the fruits of Asparagus racemosus Willd, Pharmazie, 36, 709
  17. Singh, 1991, Chemical examination of roots of Asparagus racemosus, J Indian Chem Soc, 68, 427
  18. Choudhary, 1992, Mineral contents of Asparagus racemosus, Indian Drugs, 29, 623
  19. Mohanta, 2003, Elemental profile in some common medicinal plants of India. Its correlation with traditional therapeutic usage, J Rad Anal Nucl Chem, 258, 175, 10.1023/A:1026291000167 · DOI
  20. Ahmad, 1991, Chemical examination of Shatavari Asparagus racemosus, Bull Medico-Ethano Bot Res, 12, 157
  21. Subramanian, 1968, Chemical components of Asparagus racemosus, Curr Sci, 37, 287
  22. Subramanian, 1969, Occurrence of Diosegenin in Asparagus racemosus leaves, Curr Sci, 38, 414
  23. Tambvekar, 1985, Ayurvedic drugs in common eye conditions, J Natl Integ Med Assoc, 27, 13
  24. Joglekar, 1967, Galactogogue effect of Asparagus racemosus, Indian Med J, 61, 165
  25. Sholapurkar, 1986, Lactare-for improving lactation, Indian Prac, 39, 1023
  26. Narendranath, 1986, Effect of herbal galactogogue (Lactare) a pharmacological and clinical observation, Med Surg, 26, 19
  27. Patel, 1969, Asparagus racemosus Willd. Form Bordi, as a galactogogue, in buffaloes, Indian Vet J, 46, 718
  28. Sharma, 1996, Randomized controlled trial of Asparagus racemosus (Shatavari) as a lactogogue in lactational inadequacy, Indian Pediatr, 33, 675
  29. Joglekar, 1967, Galactogogue effect of Asparagus racemosus, Indian Med J, 61, 165
  30. Singh, 1986, Clinical trial on Satavari (Asparagus racemosus Willd.) in duodenal ulcer disease, J Res Ay Sid, 7, 91
  31. Bhatnagar, 2006, Antisecretory and antiulcer activity of Asparagus racemosus Willd. Against indomethacin plus phyloric ligation-induced gastric ulcer in rats, J Herb Pharmacother, 6, 13, 10.1080/J157v06n01_02 · DOI
  32. Sairam, 2003, Gastroduodenal ulcer protective activity of Asparagus racemosus: an experimental, biochemical and histological study, J Ethnopharmacol, 86, 1, 10.1016/S0378-8741(02)00342-2 · DOI
  33. Mandal, 2000, Antitussive effect of Asparagus racemosus root against sulfur dioxide-induced cough in mice, Fitoterapia, 71, 686, 10.1016/S0367-326X(00)00151-9 · DOI
  34. Regh, 1989, Immunotherapeutic modulation of intraperitoneal adhesions by Asparagus racemosus, J Postgrad Med, 35, 199
  35. Mandal, 2000, Evaluation of antibacterial activity of Asparagus racemosus Willd. root, Phytother Res, 14, 118, 10.1002/(SICI)1099-1573(200003)14:2<118::AID-PTR493>3.0.CO;2-P · DOI
  36. Dalvi, 1990, Effect of Asparagus racemosus (Shatavari) on gastric emptying time in normal healthy volunteers, J Postgrad Med, 36, 91
  37. Kishore, 1980, Treatment of duodenal ulcer with Asparagus racemosus Linn, J Res Indian Med Yog Homeo, 15, 409
  38. Dahanukar, 1986, Protective effect of Asparagus racemosus against induced abdominal sepsis, Indian Drugs, 24, 125
  39. De, 1997, Effect of some Sitavirya drugs on gastric secretion and ulceration, Indian J Exp Biol, 35, 1084
  40. Jetmalani, 1967, A study on the pharmacology of various extracts of Shatavari-Asparagus racemosus (Willd), J Res Indian Med, 2, 1
  41. Joshi, 1988, Chemistry of Ayurvedic crude drugs: Part VIIIa-Shatavari-2: Structure elucidation of bioactive Shatavarin-I & other glycosidesb, Indian J Chem, 27, 12
  42. Pandey, 2005, Effect of Asparagus racemosus rhizome (Shatavari) on mammary gland and genital organs of pregnant rat, Phytother Res, 19, 721, 10.1002/ptr.1590 · DOI
  43. Chifundera, 1993, Phytochemical screening and molluscicidal potency of some Zairean medicinal plants, Pharmacol Res, 28, 333, 10.1006/phrs.1993.1135 · DOI
  44. Zhu, 2010, Hypolipidaemic and hepatoprotective effects of ethanolic and aqueous extracts from Asparagus officinalis L. by-products in mice fed a high-fat diet, J Sci Food Agric, 90, 1129, 10.1002/jsfa.3923 · DOI
  45. Muruganadan, 2000, Studies on the immunostimulant and antihepatotoxic activities of Asparagus racemosus root extract, J Med Arom PI Sci, 22, 49
  46. Rao, 1981, Inhibitory action of Asparagus racemosus on DMBA-induced mammary carcinogoenesis in rats, Int J Cancer, 28, 607, 10.1002/ijc.2910280512 · DOI
  47. Sabins, 1968, Effect of alcoholic extract of Asparagus racemosus on mammary glands of rats, Indian J Exp Biol, 6, 55
  48. Liu, 2009, Asparanin A induces G(2)/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, Biochem Biophys Res Commun, 381, 700, 10.1016/j.bbrc.2009.02.124 · DOI
  49. Roy, 1971, Preliminary pharmacological studies on extracts of root of Asparagus racemosus (Satavari), Willd, Lilliaceae, J Res Indian Med, 6, 132
  50. Narendranath, 1986, Effect of herbal galactogogue (Lactare) a pharmacological and clinical observation, Med Surg, 26, 19
  51. Parihar, 2004, Experimental excitotoxicity provokes oxidative damage in mice brain and attenuation by extract of Asparagus racemosus, J Neur Transm, 111, 1, 10.1007/s00702-003-0069-8 · DOI
  52. Dahanukar, 1986, Protective effect of Asparagus racemosus against induced abdominal sepsis, Indian Drugs, 24, 125
  53. Thatte, 1987, Immunotherapeutic modification of E. coli induced abdominal sepsis and mortality in mice by Indian medicinal plants, Indian Drugs, 25, 95
  54. Gautam, 2009, Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immune adjuvant potential, J Ethno Pharmacol, 121, 241, 10.1016/j.jep.2008.10.028 · DOI
  55. Gautam, 2004, Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental system, J Ethnopharmacol, 91, 251, 10.1016/j.jep.2003.12.023 · DOI
  56. Sharma, 2011, A unique immuno-stimulant steroidal sapogenin acid from the roots of Asparagus racemosus, Steroids, 76, 358, 10.1016/j.steroids.2010.12.006 · DOI
  57. Takeungwongtrakul, 2012, Lipids from cephalothorax and hepatopancreas of Pacific white shrimp (Litopenaeus vannamei): Compositions and deterioration as affected by iced storage, Food Chem, 134, 2066, 10.1016/j.foodchem.2012.04.003 · DOI
  58. Visavadiya, 2009, Suppression of reactive oxygen species and nitric oxide by Asparagus racemosus root extract using in vitro studies, Cell Mol Biol, 55, 1083
  59. Christina, 2005, Antilithiatic effect of Asparagus racemosus Willd on ethylene glycol-induced lithiasis in male albino Wistar rats, Exp Clin Pharmacol, 27, 633
  60. Goel, 2006, Teratogenicity of Asparagus racemosus Willd. root, an herbal medicine, Indian J Exp Biol, 44, 570
  61. Singh, 2009, Antidepressant activity of Asparagus racemosus in rodent models, Pharmacol Biochem Behav, 91, 283, 10.1016/j.pbb.2008.07.010 · DOI
  62. Leedo, 2009, Anti-inflammatory effects of Asparagus cochinchinensis extract in acute and chronic cutaneous inflammation, J Ethnopharmacol, 121, 28, 10.1016/j.jep.2008.07.006 · DOI
  63. Ojha, 2010, Asparagus recemosus enhances memory and protects against amnesia in rodent models, Brain Cogn, 74, 1, 10.1016/j.bandc.2010.05.009 · DOI
  64. Sharma, 2010, Effect of Convolvulus pluricaulis Choisy and Asparagus racemosus Willd on learning and memory in young and old mice, a comparative evaluation, Indian J Exp Biol, 48, 479
  65. Thakur, 2009, A comparative study on aphrodisiac activity of some ayurvedic herbs in male albino rats, Arch Sex Behav, 38, 1009, 10.1007/s10508-008-9444-8 · DOI
  66. Kumar, 2010, Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd. in rats, West Indian Med J, 59, 3, 10.4103/0019-5359.13811 · DOI
  67. Agrawal, 2008, The effect of the aqueous extract of the roots of Asparagus racemosus on hepatocarcinogenesis initiated by diethyl nitrosamine, Phytother Res, 22, 1175, 10.1002/ptr.2391 · DOI
  68. Kanwar, 2010, Effects of Chlorophytum arundinaceum, Asparagus adscendens and Asparagus racemosus on pro-inflammatory cytokine and corticosterone levels produced by stress, Phytother Res, 24, 1562, 10.1002/ptr.3218 · DOI
  69. Joshi, 2012, Antistress activity of ethanolic extract of Asparagus racemosus Willd roots in mice, Indian J Exp Biol, 50, 419
  70. Hannan, 2007, Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta-cells, J Endocrinol, 192, 159, 10.1677/joe.1.07084 · DOI
  71. Sharma, 2011, Asparagus racemosus (Shatavari): A versatile female tonic, Int J Pharm Biol Arch, 2, 855
  72. Karmakar, 2012, Cytotoxicity, analgesic and antidiarrhoeal activities of Asparagus racemosus, J Appl Sci, 12, 581, 10.3923/jas.2012.581.586 · DOI
  73. Narumalla, 2012, Study of antiurolithiatic activity of Asparagus racemosus on albino rats, Indian J Pharmacol, 44, 576, 10.4103/0253-7613.100378 · DOI

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Metadata

Authors
Alok, S., Jain, S. K., Verma, A., Kumar, M., Mahor, A., & Sabharwal, M.
Affiliations
  • Bundelkhand University (IN)
  • Sam Higginbottom Institute of Agriculture (IN)
  • Society of Pharmaceutical Sciences and Research (IN)
Corresponding author
Alok, Shashi
ORCID
Venue
Asian Pacific Journal of Tropical Disease
Publisher
Elsevier BV
Published
2013-04
Volume
3
Issue
3
Pages
242-251
ISSN
2222-1808 (ISSN-L)
DOI
10.1016/s2222-1808(13)60049-3
PMC
PMC4027291
OpenAlex
W1978680385
Cited by
292
References
0
Citations by year
2026: 34 · 2025: 40 · 2024: 40 · 2023: 37 · 2022: 35 · 2021: 37 · 2020: 19 · 2019: 9 · 2018: 10 · 2017: 10 · 2016: 8 · 2015: 7 · 2014: 3 · 2013: 3
FWCI
16.45
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Asian Pacific Journal of Tropical Disease (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Keywords
Asparagus racemosus, phytochemistry, pharmacology, root extract, galactagogues, immunomodulation, immunoadjuvant, antilithiatic activity, teratogenicity, ulcer healing, Ayurveda, medicinal plants

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