A randomised, controlled, crossover study of the effect of diet on angiopoietin-like protein 4 (ANGPTL4) through modification of the gut microbiome

Blædel, Trine; Holm, Jacob B.; Sundekilde, Ulrik K.; Schmedes, Mette S.; Hess, Anne L.; Lorenzen, Janne K.; Kristiansen, Karsten; Dalsgaard, Trine K.; Astrup, Arne; Larsen, Lesli H.

doi:10.1017/jns.2016.38

A randomised, controlled, crossover study of the effect of diet on angiopoietin-like protein 4 (ANGPTL4) through modification of the gut microbiome

Angiopoietin-like protein 4 (ANGPTL4) is a lipoprotein lipase inhibitor that is involved in lipid metabolism and angiogenesis. Animal studies have suggested that the ANGPTL4 protein is modulated by the gut microbiota, possibly through increased concentrations of SCFA, such as C4, found in whole-f…