A comprehensive systematic review dataset is a rich resource for training and evaluation of AI systems for title and abstract screening
Open accessAbstract
When conducting a systematic review, screening the vast body of literature to identify the small set of relevant studies is a labour-intensive and error-prone process. Although there is an increasing number of fully automated tools for screening, their performance is suboptimal and varies substantially across review topic areas. Many of these tools are only trained on small datasets, and most are not tested on a wide range of review topic areas. This study presents two systematic review datasets compiled from more than 8600 systematic reviews and more than 540000 abstracts covering 51 research topic areas in health and medical research. These datasets are the largest of their kinds to date. We demonstrate their utility in training and evaluating language models for title and abstract screening. Our dataset includes detailed metadata of each review, including title, background, objectives and selection criteria. We demonstrated that a small language model trained on this dataset with additional metadata has excellent performance with an average recall above 95% and specificity over 70% across a wide range of review topic areas. Future research can build on our dataset to further improve the performance of fully automated tools for systematic review title and abstract screening.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The Chan et al BioBERT Siamese network achieved mean specificity of 70.9% with a 31% false-negative rate on one review.
“their BioBERT Siamese network achieved mean specificity of 70.9% with a 31% false-negative rate on one review”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Scaling Laws for Neural Language Models
Kaplan, J., McCandlish, S., Henighan, T., Brown, T. B., Chess, B., Child, R., Gray, S., Radford, A., Wu, J., & Amodei, D. (2020) · arXiv · Cited by 1,749 · see citing works
An open source machine learning framework for efficient and transparent systematic reviews
van de Schoot, R., de Bruin, J., Schram, R., Zahedi, P., de Boer, J., Weijdema, F., Kramer, B., Huijts, M., Hoogerwerf, M., Ferdinands, G., et al. (2021) · Nature Machine Intelligence · doi:10.1038/s42256-020-00287-7 · Cited by 1,157 · see citing works
Borah, R., Brown, A. W., Capers, P. L., & Kaiser, K. A. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-012545 · Cited by 737 · see citing works
QLoRA: Efficient Finetuning of Quantized LLMs
Dettmers, T., Pagnoni, A., Holtzman, A., & Zettlemoyer, L. (2023) · arXiv · doi:10.48550/arxiv.2305.14314 · Cited by 507 · see citing works
Khraisha, Q., Put, S., Kappenberg, J., Warraitch, A., & Hadfield, K. (2024) · Research Synthesis Methods · doi:10.1002/jrsm.1715 · Cited by 269 · see citing works
Khraisha, Q., Put, S., Kappenberg, J., Warraitch, A., & Hadfield, K. (2023) · arXiv · doi:10.48550/arxiv.2310.17526 · Cited by 268 · see citing works
Error rates of human reviewers during abstract screening in systematic reviews
Wang, Z., Nayfeh, T., Tetzlaff, J., O’Blenis, P., & Murad, M. H. (2020) · PLOS ONE · doi:10.1371/journal.pone.0227742 · Cited by 217 · see citing works
Tools to support the automation of systematic reviews: a scoping review.
Khalil, H., Ameen, D., & Zarnegar, A. (2022) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2021.12.005 · Cited by 190 · see citing works
Prioritising references for systematic reviews with RobotAnalyst: A user study
Przybyła, P., Brockmeier, A. J., Kontonatsios, G., Le Pogam, M., McNaught, J., von Elm, E., Nolan, K., & Ananiadou, S. (2018) · Research Synthesis Methods · doi:10.1002/jrsm.1311 · Cited by 148 · see citing works
A Survey on Mixture of Experts
Cai, W., Jiang, J., Wang, F., Tang, J., Kim, S., & Huang, J. (2024) · doi:10.36227/techrxiv.172055626.64129172/v1 · Cited by 92 · see citing works
Precision of healthcare systematic review searches in a cross‐sectional sample
Sampson, M., Tetzlaff, J., & Urquhart, C. (2011) · Research Synthesis Methods · doi:10.1002/jrsm.42 · Cited by 80 · see citing works
SYNERGY - Open machine learning dataset on study selection in systematic reviews
De Bruin, J., Ma, Y., Ferdinands, G., Teijema, J., & Van de Schoot, R. (2023) · DataverseNL · doi:10.34894/he6naq · Cited by 20 · see citing works
Flagged first, then by citations
Research works printed but not linked: 16
- [1]Leung J, Ferrari A, Baxter A, Schoultz M, Beattie M, Harris M. Systematic reviews: inducting research students into scholarly conversations? Higher Educ Res Dev. 2017; 36(1): 217– 220.
- [6]Feng Y, Liang S, Zhang Y, et al. Automated medical literature screening using artificial intelligence: a systematic review and meta-analysis. J Am Med Inform Assoc. 2022; 29(8): 1425– 1432. 35641139 PMC9277646
- [7]Chappell M, Edwards M, Watkins D, Marshall C, Graziadio S. Machine learning for accelerating screening in evidence reviews. Cochrane Evidence Synth Methods. 2023; 1(5):e12021. PMC11795896 40475071
- [8]Halman A, Oshlack A. Catchii: Empowering literature review screening in healthcare. Res Synth Methods. 2024; 15(1): 157– 165. 37771210
- [10]Aum S, Choe S. srBERT: automatic article classification model for systematic review using BERT. Syst Rev. 2021; 10: 1– 8. 34717768 PMC8556883
- [11]Sadri N, Cormack GV. Continuous active learning using pretrained transformers. arXiv preprint arXiv:220806955. 2022;
- [14]Alharbi A, Stevenson M. A dataset of systematic review updates. In: SIGIR’19: Proceedings of the 42nd International ACM SIGIR Conference on Research and Development in Information Retrieval. 2019: 1257– 1260. doi: 10.1145/3331184.3331358 · DOI
- [16]Šuster S, Baldwin T, Verspoor K. Analysis of predictive performance and reliability of classifiers for quality assessment of medical evidence revealed important variation by medical area. J Clin Epidemiol. 2023; 159: 58– 69. 37120028
- [17]Wang S, Scells H, Koopman B, Zuccon G. Neural rankers for effective screening prioritisation in medical systematic review literature search. In: ADCS ’22: Proceedings of the 26th Australasian Document Computing Symposium. Article No.: 4, 2022: 1– 10. doi: 10.1145/3572960.3572980 · DOI
- [18]Robinson A, Thorne W, Wu BP, et al. Bio-sieve: Exploring instruction tuning large language models for systematic review automation. arXiv preprint arXiv:230806610. 2023.
- [19]Schiavo JH. PROSPERO: an international register of systematic review protocols. Med Ref Serv Q. 2019; 38(2): 171– 180. 31173570
- [20]Reimers N, Gurevych I. Sentence-bert: sentence embeddings using siamese bert-networks. arXiv preprint arXiv:190810084. 2019.
- [21]Lee J, Yoon W, Kim S, et al. BioBERT: a pre-trained biomedical language representation model for biomedical text mining. Bioinformatics. 2020; 36(4): 1234– 1240. 31501885 PMC7703786
- [22]Devlin J, Chang M-W, Lee K, Toutanova K. BERT: Pre-training of deep bidirectional transformers for language understanding. arXiv preprint arXiv:181004805. 2018.
- [23]Wang S, Scells H, Clark J, Koopman B, Zuccon G. From little things big things grow: a collection with seed studies for medical systematic review literature search. 2022: 3176– 3186.
- [25]Brown TB, NBenjamin M, Ryder N, et al. Language models are few-shot learners. arXiv preprint arXiv:200514165. 2020.
Cited by
Sorted by citations
Pitre, T., Zeraatkar, D., Granton, J., Busse, J., Rochwerg, B., & Guyatt, G. (2026) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2026.112514 · Cited by 2 · see citing works
- Authors
- Chan, G. C. K., He, E., Leung, J., & Verspoor, K.
- Affiliations
- The University of Queensland (AU)
- RMIT University (AU)
- The University of Melbourne (AU)
- Corresponding author
- Chan, Gary C. K.
- Venue
- Research Synthesis Methods
- Publisher
- Cambridge University Press (CUP)
- Published
- 2025-03
- Volume
- 16
- Issue
- 2
- Pages
- 308-322
- ISSN
- 1759-2879 (ISSN-L)
- 1759-2887
- PMC
- PMC12527522
- OpenAlex
- W4408236898
- Cited by
- 10
- References
- 12
- Citations by year
- 2026: 8 · 2025: 2
- FWCI
- 1.90
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Research Synthesis Methods (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Computer Science › Information Systems › Information Retrieval and Search Behavior
- Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
- Keywords
- abstract screening, language models, AI-assisted literature screening, data curation
- MeSH terms
- Metadata, Systematic Reviews as Topic, Artificial Intelligence, Humans, Natural Language Processing, Reproducibility of Results
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review