The DOI matches its Crossref record.
Behavioural sensitization to daily life stress in psychosis
Abstract
BACKGROUND: Recent neurobiological models provide a possible mechanism of daily life stress directly affecting the intensity of psychotic experiences in vulnerable individuals. In order to validate such a mechanism, the impact of daily life stress on psychosis intensity was investigated in two groups at increased risk of onset (relatives) and relapse (patients) of psychosis. METHOD: Patients with psychosis in a clinical state of remission (n = 42), first-degree relatives (n = 47), and control subjects (n = 49) were studied with the Experiencing Sampling Method (ESM is a structured diary technique assessing current context and psychopathology in daily life) to assess (1) appraised subjective stress related to daily activities and events, and (2) intensity of subtle psychotic experiences in daily life. RESULTS: Multilevel regression analyses revealed significant increases in psychosis intensity associated with increases in subjective activity--and event-related stress in patients. First-degree relatives reported increases in psychosis intensity in relation to activity-related stress but not event-related stress. No association was found in control subjects. CONCLUSIONS: Subjects at increased risk for psychosis show continuous variation in the intensity of subtle psychotic experiences associated with minor stresses in the flow of daily life. Behavioural sensitization to environmental stress may therefore be a vulnerability marker for schizophrenia, reflecting dopaminergic hyper-responsivity in response to environmental stimuli.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“which binds PNNs without causing any inflammatory processes (56)”
From Perineuronal nets protect fast-spiking interneurons against oxidative stress (2013) · cites this paper as [56]
In the citing paper
“This phenomenon may be explained in part by the fact that the level of distress experienced is proportional to the intensity of psychotic symptoms reported (41).”
From Mobile intervention for individuals with psychosis, dual disorders, and their common comorbidities: A literature review (2019) · cites this paper as [41]
Citations
Cited by
Sorted by citations
The environment and schizophrenia
van Os, J., Kenis, G., & Rutten, B. P. F. (2010) · Nature · doi:10.1038/nature09563 · Cited by 1,572
Self-citationSchizophrenia: an integrated sociodevelopmental-cognitive model
Howes, O. D., & Murray, R. M. (2014) · The Lancet · doi:10.1016/s0140-6736(13)62036-x · Cited by 864
Experience sampling research in psychopathology: opening the black box of daily life
Myin-Germeys, I., Oorschot, M., Collip, D., Lataster, J., Delespaul, P., & van Os, J. (2009) · Psychological Medicine · doi:10.1017/s0033291708004947 · Cited by 817
“Another study in psychosis demonstrated that dopamine release induced by a physical stressor in the laboratory was associated with psychotic reactivity to daily life stress in first-degree relatives of patients with psychosis (Myin-Germeys et al. 2005b).”
BackgroundSelf-citationSuspicious minds: The psychology of persecutory delusions
Freeman, D. (2007) · Clinical Psychology Review · doi:10.1016/j.cpr.2006.10.004 · Cited by 814
Experience sampling methodology in mental health research: new insights and technical developments.
Myin‐Germeys, I., Kasanova, Z., Vaessen, T., Vachon, H., Kirtley, O., Viechtbauer, W., & Reininghaus, U. (2018) · World Psychiatry · doi:10.1002/wps.20513 · Cited by 709
Self-citation
Metadata
- Authors
- MYIN-GERMEYS, I., DELESPAUL, P., & VAN OS, J.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2005-01-05
- Volume
- 35
- Issue
- 5
- Pages
- 733-741
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2142678392
- Cited by
- 292
- References
- 0
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 9 · 2023: 11 · 2022: 7 · 2021: 16 · 2020: 9 · 2019: 9 · 2018: 11 · 2017: 10 · 2016: 15 · 2015: 14 · 2014: 18 · 2013: 22 · 2012: 14
- FWCI
- 10.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Lirias (KU Leuven) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- psychosis, daily stress, behavioral sensitization, first-degree relatives, schizophrenia, vulnerability indicators, relapse risk
- MeSH terms
- Adult, Female, Humans, Life Change Events, Male, Middle Aged, Periodicity, Psychotic Disorders, Regression Analysis, Social Environment, Stress, Psychological
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
