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Work stress precipitates depression and anxiety in young, working women and men
Open accessAbstract
BACKGROUND: Rates of depression have been rising, as have rates of work stress. We tested the influence of work stress on diagnosed depression and anxiety in young working adults. METHOD: Participants were enrolled in the Dunedin study, a 1972-1973 longitudinal birth cohort assessed most recently in 2004-2005, at age 32 (n=972, 96% of 1015 cohort members still alive). Work stress (psychological job demands, work decision latitude, low work social support, physical work demands) was ascertained by interview. Major depressive disorder (MDD) and generalized anxiety disorder (GAD) were ascertained using the Diagnostic Interview Schedule (DIS) and diagnosed according to DSM-IV criteria. RESULTS: Participants exposed to high psychological job demands (excessive workload, extreme time pressures) had a twofold risk of MDD or GAD compared to those with low job demands. Relative risks (RRs) adjusting for all work characteristics were: 1.90 [95% confidence interval (CI) 1.22-2.98] in women, and 2.00 (95% CI 1.13-3.56) in men. Analyses ruled out the possibility that the association between work stress and disorder resulted from study members' socio-economic position, a personality tendency to report negatively, or a history of psychiatric disorder prior to labour-market entry. Prospective longitudinal analyses showed that high-demand jobs were associated with the onset of new depression and anxiety disorder in individuals without any pre-job history of diagnosis or treatment for either disorder. CONCLUSIONS: Work stress appears to precipitate diagnosable depression and anxiety in previously healthy young workers. Helping workers cope with work stress or reducing work stress levels could prevent the occurrence of clinically significant depression and anxiety.
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“This is particularly encouraging, as longitudinal data shows that high work stress may lead to depression and anxiety, even in individuals with no previous history of disorder [15].”
From A pilot evaluation of a smartphone application for workplace depression (2020) · cites this paper as [15]
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Metadata
- Authors
- MELCHIOR, M., CASPI, A., MILNE, B. J., DANESE, A., POULTON, R., & MOFFITT, T. E.
- Affiliations
- University of Wisconsin–Madison (US)
- King's College London (GB)
- University of Otago (NZ)
- Corresponding author
- MOFFITT, TERRIE E.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2007-04-04
- Volume
- 37
- Issue
- 8
- Pages
- 1119-1129
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- PMC
- PMC2062493
- OpenAlex
- W2143082772
- Cited by
- 691
- References
- 50
- Citations by year
- 2026: 33 · 2025: 47 · 2024: 35 · 2023: 45 · 2022: 49 · 2021: 74 · 2020: 46 · 2019: 39 · 2018: 41 · 2017: 27 · 2016: 30 · 2015: 35 · 2014: 33 · 2013: 36 · 2012: 29
- FWCI
- 41.96
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- HAL (submittedVersion, other-oa)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Employment and Welfare Studies
- Social Sciences › Psychology › Social Psychology › Stress and Burnout Research
- Keywords
- occupational stress, depression, anxiety, major depressive disorder, generalized anxiety disorder, psychological job demands, workload, time pressure, physical work demands, young working adults, sex differences, Dunedin birth cohort
- MeSH terms
- Adult, Anxiety Disorders, Cross-Sectional Studies, Major Depressive Disorder, Female, Health Surveys, Humans, Job Satisfaction, Longitudinal Studies, Male, New Zealand, Occupational Diseases, Risk Factors, Sex Factors, Socioeconomic Factors, Stress, Psychological, Temperament, Cohort Studies, Workload
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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